A5032224273- Economic and Financial Impacts of Cancer
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Cancer Immunotherapy and Biomarkers
- Biomedical Ethics and Regulation
- Multiple and Secondary Primary Cancers
- Neutropenia and Cancer Infections
- Healthcare Policy and Management
- Pharmaceutical studies and practices
- Hepatitis B Virus Studies
- Patient-Provider Communication in Healthcare
- Radiomics and Machine Learning in Medical Imaging
- Hepatitis Viruses Studies and Epidemiology
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- CAR-T cell therapy research
- Vaccine Coverage and Hesitancy
Ben-Gurion University of the Negev
2022-2024
Bar-Ilan University
2016-2021
Modern immuno-oncology agents have generated great excitement because of their potential to provide durable survival for some patients. However, there is concern regarding the cost cancer care, and multiple frameworks been developed assess value. The American Society Clinical Oncology (ASCO) framework awards bonus points if substantial demonstrated.To whether modern reach defined efficacy thresholds in value frameworks.In this analysis, all US Food Drug Administration (FDA) approvals between...
Abstract Introduction Understanding the efficacy of treatments is crucial for patients, physicians, and policymakers. Median survival, most common measure used in outcome reporting oncology clinical trials, easy to understand; however, it describes only a single time point. The interpretation hazard ratio difficult, its underlying statistical assumptions are not always met. objective this study was evaluate alternative measures based on mean benefit novel treatments. Materials Methods We...
Increasing health costs in developed countries are a major concern for decision makers. A variety of cost containment tools used to control this trend, including maximum price regulation and reimbursement methods technologies. Information regarding expenditure-related outcomes these is not available.To evaluate the association between different cost-regulating mechanisms national expenditures selected countries.Price-regulating prescription drugs among OECD were reviewed. National...
Abstract Background mRNA technology is currently being investigated for a range of oncology indications. We assessed the willingness to pay (WTP) general population in Israel hypothetical novel mRNA-based treatment Methods used contingent valuation methodology elicit WTP using web-based questionnaire. A sample adult participants were presented with scenario which an intervention increased likelihood cure various cancer types from 20% 40% (half sample), or 60% (the other half sample). Results...
PURPOSE: A unique feature of immuno-oncology agents is the potential for durable survival a subset patients; however, this benefit usually cannot not be seen in early published data used regulatory approval. Value frameworks developed by ASCO and European Society Medical Oncology (ESMO) assess clinical demonstrated trials. Proven may change with time as more mature are available. Our objective was to evaluate impact on ESMO scores examine concordance these using data. METHODS: We reviewed...
6624 Background: Patented anti-cancer drugs launch prices have increased in recent years with subsequent increases after launch. Recently, large price of generic were at the center public attention United States. Our aim was to assess changes time for Medicare part B and understand how drug characteristics market structure influence trajectories. Methods: We included all reported both 2006 2016. Patent expiration dates attached using Drug Expiration engine a patent date later than excluded....
6601 Background: Modern immuno-oncologic agents may have the potential to provide durable survival for some patients. Simultaneously, there is growing concern regarding cost of cancer care, and multiple frameworks been developed assess value. The points based framework created by American Society Clinical Oncology (ASCO) has a specific threshold, more are awarded if substantial demonstrated. objective this study was modern reach defined efficacy thresholds in framework. Methods: We...