A5071081642- Prostate Cancer Diagnosis and Treatment
- Urinary Bladder and Prostate Research
- Prostate Cancer Treatment and Research
- Urological Disorders and Treatments
- Urologic and reproductive health conditions
- Pelvic floor disorders treatments
- Bladder and Urothelial Cancer Treatments
- Hormonal and reproductive studies
- Kidney Stones and Urolithiasis Treatments
- Sexual function and dysfunction studies
- Genital Health and Disease
- Urinary Tract Infections Management
- Cancer, Lipids, and Metabolism
- Urinary and Genital Oncology Studies
- Male Reproductive Health Studies
- Pediatric Urology and Nephrology Studies
- Poisoning and overdose treatments
- Ureteral procedures and complications
- Anesthesia and Pain Management
- Colorectal Cancer Screening and Detection
- Phosphodiesterase function and regulation
- Colorectal Cancer Surgical Treatments
- Intraocular Surgery and Lenses
- Gastrointestinal disorders and treatments
- Neurological Disorders and Treatments
East and North Hertfordshire NHS Trust
2014-2020
Lister Hospital
2009-2018
Hitchin Hospital
2018
University of Hertfordshire
2006-2016
Royal Society of Medicine
2016
The University of Sydney
2011
The Prostate Centre
2010
University of Glasgow
2010
Royal College of Surgeons of England
1990-2005
University Hospital of Wales
2005
To assess the possible relationship between erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) in men, whether treatment of their ED with sildenafil influences LUTS.In all, 112 men attending andrology outpatient clinic were offered oral reviewed 1 3 months after treatment. They completed International Index Erectile Function Prostate Symptom Score (IPSS) questionnaires at baseline each review. Scores designated to indicate visit number differences visits calculated.A third had...
Study Type – Therapy (case series) Level of Evidence 4 What’s known on the subject? and What does study add? Most surgical treatments for benign prostatic hyperplasia procedural involve removal or destruction prostate tissue these approaches are commonly associated with treatment related morbidity. Unlike other therapies, urethral lift mechanically opens urethra using tensioned sutures that compress between capsule. This is first publication this technology. manuscript reports confirms its...
To test the sensitivity, specificity and accuracy of serum prostate-specific antigen isoform [-2]proPSA (p2PSA), %p2PSA prostate health index (PHI), in men with a family history cancer (PCa) undergoing biopsy for suspected PCa. evaluate potential reduction unnecessary biopsies characteristics potentially missed cases PCa that would result from using p2PSA, PHI.The analysis consisted nested case-control study PRO-PSA Multicentric European Study, PROMEtheuS project. All patients had...
OBJECTIVE To compare the safety and efficacy of two doses a new testosterone gel formulation (Testim™, Auxilium Pharmaceuticals, Inc., Norristown, PA, USA) to permeation‐enhanced patch (Andropatch®, GlaxoSmithKline, UK) for treating men with confirmed low serum levels, associated signs symptoms hypogonadism. PATIENTS AND METHODS In all, 208 were randomized treated at 29 centres in Denmark, Germany, Netherlands, Sweden UK. The 90 days, pharmacokinetics treatment effectiveness Testim (50 100...
Summary— Extracorporeal shockwave lithotripsy has been shown to be a safe and effective method of treating most upper urinary tract stones. Major complications, although few, include haemorrhage, septicaemia, “Steinstrasse” formation cardiac arrhythmias. The experience from 600 consecutive cases is reviewed methods prevention are discussed.
Objectives To compare the nuclear matrix protein (NMP)‐22 assay, bladder tumour specific antigen (BTAstat) test, telomerase activity (using telomeric repeat amplification protocol TRAP) and a haemoglobin dipstick test for their ability to replace voided urine cytology (VUC) detecting cancer. Patients methods The study included 120 urological patients prospectively recruited assessed before surgery. A single freshly sample (≈100 mL) was collected from each patient aliquoted test. All assays...
<i>Background/Aims:</i> Retroperitoneal fibrosis (RPF) is a chronic inflammatory disorder causing obstructive nephropathy and renal failure. We reviewed our management of this condition. <i>Method:</i> All patients with RPF treated at single center over 15-year period were identified. A full review notes computer records was undertaken. <i>Results:</i> Data available on 27 patients, 3 which excluded from later analysis. Diagnosis based clinical history...
Objective To determine the prevalence of previously undiagnosed diabetes mellitus (DM) in men presenting with erectile dysfunction (ED), using fasting blood glucose (FBG) compared urinary dipstick testing for glycosuria. Patients and methods A prospective study was carried out an andrology outpatient clinic a urology department district general hospital serving mixed urban rural population. In all, 129 consecutive ED underwent FBG to detect DM those ED. Results The known 17% that 4.7% 107...
To test the hypothesis that [-2]proPSA (p2PSA) and its derivatives are more accurate than total prostate-specific antigen (tPSA), free (fPSA) fPSA as percentage of tPSA (%fPSA) in detecting prostate cancer (PCa) men aged <60 years.The analysis consisted a nested case-control study from PRO- PSA Multicentric European Study (PROMEtheuS) project. The primary outcomes were measures sensibility, specificity accuracy serum p2PSA, p2PSA (%p2PSA) Beckman Coulter health index (PHI) years who had...
Objective To determine the acceptability and patient satisfaction of transrectal biopsy undertaken with under sedation. Patients methods A retrospective questionnaire was sent to 100 patients who had undergone between January August 1998. Levels were assessed using visual analogue scales (VAS, a maximum score 10 being least satisfactory or acceptable) direct questions about side‐effects procedure. subsequent prospective study on 130 undergoing sedation 1999 2000. Results The mean for...
Summary— Of 211 patients with urethral strictures undergoing one‐stage dartos pedicled island patch urethroplasty between 1970 and 1987, 194 have been followed up from 3 to 20 years. There was 1 post‐operative death (from hepatitis). During the period of follow‐up, recurred in 14 (7%), some them as late 15 years after an apparently successful urethroplasty. Calculi forming on hairs required treatment 6 (3%) it necessary revise a redundant skin pouch 6.
Study Type – Therapy (case series) Level of Evidence 4 What's known on the subject? and What does study add? Several sets comprehensive treatment guidelines (national international) exist for managing male lower urinary tract symptoms (LUTS), but these are not widely adopted in primary secondary care, consistently applied across Europe. This paper will improve consistency approaches adult males with LUTS by providing a clear, concise summary existing that can be easily urologists care...
To test serum prostate-specific antigen (PSA) isoform [-2]proPSA (p2PSA), p2PSA/free PSA (%p2PSA) and Prostate Health Index (PHI) accuracy in predicting prostate cancer obese men to whether PHI is more accurate than patients.The analysis consisted of a nested case-control study from the pro-PSA Multicentric European Study (PROMEtheuS) project. The registered at http://www.controlled-trials.com/ISRCTN04707454. primary outcome was sensitivity, specificity (clinical validity) p2PSA, %p2PSA PHI,...