- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Pelvic floor disorders treatments
- Urological Disorders and Treatments
- Hormonal and reproductive studies
- Urologic and reproductive health conditions
- Sexual function and dysfunction studies
- Prostate Cancer Treatment and Research
- Urinary Tract Infections Management
- Bladder and Urothelial Cancer Treatments
- Pediatric Urology and Nephrology Studies
- Organ Donation and Transplantation
- Sexual Differentiation and Disorders
- Renal and Vascular Pathologies
- Multiple and Secondary Primary Cancers
- Alcohol Consumption and Health Effects
- Renal and related cancers
- Global Cancer Incidence and Screening
- Aldose Reductase and Taurine
- Genital Health and Disease
- Neuropeptides and Animal Physiology
- Opioid Use Disorder Treatment
- Hydraulic Fracturing and Reservoir Analysis
- Oil and Gas Production Techniques
- Veterinary Medicine and Surgery
University of Vermont
2006-2025
University of Vermont Medical Center
2002-2023
Indianapolis Zoo
2020
University of Richmond
2020
New York Proton Center
2020
Albany Research Institute
2020
Boston Children's Hospital
2013
Los Alamos National Laboratory
2013
Proton (Malaysia)
2013
Ball (France)
2013
We compared the safety and efficacy of Aquablation transurethral prostate resection for treatment lower urinary tract symptoms related to benign prostatic hyperplasia.In a double-blind, multicenter, prospective, randomized, controlled trial 181 patients with moderate severe hyperplasia underwent or Aquablation. The primary end point was reduction in International Prostate Symptom Score at 6 months. development Clavien-Dindo persistent grade 1, 2 higher operative complications.Mean total time...
Based on previous studies that demonstrated the safety profile and preliminary clinical activity of prostate specific antigen (PSA) targeted therapeutic vaccines, as well recent laboratory data supporting value addition co-stimulatory molecules B7-1, ICAM-1, LFA-3 (designated TRICOM) to these we conducted a Phase I study evaluate immunogenicity novel vaccinia fowlpox vaccine incorporating PSA gene sequence TRICOM.In this study, ten patients with androgen independent cancer or without...
Study Type – Therapy (case series) Level of Evidence 4 What’s known on the subject? and What does study add? Most surgical treatments for benign prostatic hyperplasia procedural involve removal or destruction prostate tissue these approaches are commonly associated with treatment related morbidity. Unlike other therapies, urethral lift mechanically opens urethra using tensioned sutures that compress between capsule. This is first publication this technology. manuscript reports confirms its...
We report 5-year safety and efficacy outcomes of the Aquablation procedure for treatment men with symptomatic benign prostatic hyperplasia large-volume prostate glands.A total 101 moderate to severe symptoms volumes between 80 150 mL underwent a robotic-assisted in prospective multicenter international trial (NCT03123250). Herein we final results.The study successfully met its performance goal, which was based upon transurethral resection typically done smaller prostates, at 3 months. Mean...
To present early safety and feasibility data from a multicentre prospective study (WATER II) of aquablation in the treatment symptomatic men with large-volume benign prostatic hyperplasia (BPH).Between September December 2017, 101 moderate-to-severe BPH symptoms prostate volume 80-150 mL underwent international clinical trial. Baseline demographics standardized postoperative management variables were carefully recorded central independently monitored database. Surgeons answered analogue...
To present 6-month safety and effectiveness data from a multicentre prospective study of aquablation in men with lower urinary tract symptoms (LUTS) attributable to benign prostatic hyperplasia (BPH) prostate volumes between 80 150 mL.Between September December 2017, 101 LUTSattributable BPHwere prospectively enrolled at 16 centres Canada the USA.The mean volume was 107 mL. The length hospital stay after procedure 1.6 days (range: same day 6 days). primary endpoint (Clavien-Dindo grade 2 or...
To report 12-month safety and effectiveness outcomes of the Aquablation procedure for treatment men with symptomatic benign prostatic hyperplasia (BPH) large-volume prostates.One hundred one moderate-to-severe BPH symptoms prostate volumes 80-150 cc underwent a robotic-assisted in prospective multicenter international clinical trial. Functional were assessed at 12 months postoperatively.Mean volume was 107 (range 80-150). Mean operative time 37 minutes mean resection 8 minutes. The average...
To compare 2-year safety and efficacy outcomes after Aquablation or transurethral resection of the prostate (TURP) for treatment lower urinary tract symptoms related to benign hyperplasia (BPH). One hundred eighty-one patients with BPH were assigned at random (2:1 ratio) either TURP. Patients follow-up assessors blinded treatment. Assessments included International Prostate Symptom Score (IPSS), Male Sexual Health Questionnaire (MSHQ), Index Erectile Function uroflow. The focus analysis was...
To test the hypothesis that benign prostatic hyperplasia (BPH) robotic surgery with aquablation would have a more pronounced benefit in certain patient subgroups, such as men challenging anatomies (e.g. large prostates, middle lobes) and moderate BPH.We conducted prespecified post hoc exploratory subgroup analyses from double-blind, multicentre prospective randomized controlled trial compared transurethral resection of prostate (TURP) using either standard electrocautery vs waterjet...
We examine the association of family history and prostatic carcinoma.A total 2,968 consecutive patients referred for prostate cancer detection responded to a questionnaire underwent transrectal ultrasound examination with or without biopsy.Of men 329 (11.1%) had cancer. No differences were observed between groups respect mean patient age, serum specific antigen level biopsy rate. Prostate was detected in 133 (40.4%) 769 2,639 (29.1) no (p < 0.001, odds ratio 1.7). significant Gleason score...
The objective of this study is to determine if Aquablation therapy can maintain its effectiveness in treating men with lower urinary tract symptoms (LUTS) due benign prostatic hyperplasia (BPH) large-volume (80-150 cc) prostates at 3 years. One hundred one moderate-to-severe BPH and prostate volumes between 80 150 cc were enrolled a prospective, nonrandomized, multicenter, international clinical trial late 2017. Baseline, procedural, follow-up parameters recorded baseline scheduled...
No AccessJournal of UrologyClinical Urology: Original Article1 Aug 1995Family History and the Risk Prostatic Carcinoma in a High Group Urological Patients Armen G.* Aprikian, Michel Bazinet, Mark Plante, Alaa Meshref, Claude Trudel, Samuel Aronson, Mahmoud Nachabe, Francois Peloquin, Jean Dessureault, Steven Narod, Louis Begin, Mostafa M. Elhilali AprikianArmen Aprikian , BazinetMichel Bazinet PlanteMark Plante MeshrefAlaa Meshref TrudelClaude Trudel AronsonSamuel Aronson NachabeMahmoud...
No AccessJournal of UrologyINVESTIGATIVE UROLOGY1 Dec 2002Differential Expression Bladder Neurotrophic Factor mRNA in Male and Female Rats After Outflow Obstruction PETER ZVARA, JAN KLIMENT, ANTHONY L. DeROSS, BRIAN H. IRWIN, SUSAN E. MALLEY, MARK K. PLANTE, MARGARET A. VIZZARD ZVARAPETER ZVARA , KLIMENTJAN KLIMENT DeROSSANTHONY DeROSS IRWINBRIAN IRWIN MALLEYSUSAN MALLEY PLANTEMARK PLANTE VIZZARDMARGARET View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64244-9AboutFull...