A5045356209- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Urological Disorders and Treatments
- Prostate Cancer Diagnosis and Treatment
- Urinary Tract Infections Management
- Ureteral procedures and complications
- Anorectal Disease Treatments and Outcomes
- Bladder and Urothelial Cancer Treatments
- Pelvic and Acetabular Injuries
- Pediatric Urology and Nephrology Studies
- Sexual function and dysfunction studies
- Kidney Stones and Urolithiasis Treatments
- Hernia repair and management
- Hormonal and reproductive studies
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Diverticular Disease and Complications
- Sexual Differentiation and Disorders
- Tissue Engineering and Regenerative Medicine
- Diversity and Career in Medicine
- Acute Ischemic Stroke Management
- Cardiac, Anesthesia and Surgical Outcomes
- Renal cell carcinoma treatment
- Infectious Disease Case Reports and Treatments
- Surgical Simulation and Training
Atrium Health Wake Forest Baptist
2016-2025
Wake Forest University
2015-2024
W. G. (Bill) Hefner VA Medical Center
2022-2024
Evidence (Italy)
2023
Michigan Department of Education
2023
Forest Institute
2022-2023
American Urological Association
2023
Florida International University
2023
Indianapolis Zoo
2020
University of Richmond
2020
We compared the safety and efficacy of Aquablation transurethral prostate resection for treatment lower urinary tract symptoms related to benign prostatic hyperplasia.In a double-blind, multicenter, prospective, randomized, controlled trial 181 patients with moderate severe hyperplasia underwent or Aquablation. The primary end point was reduction in International Prostate Symptom Score at 6 months. development Clavien-Dindo persistent grade 1, 2 higher operative complications.Mean total time...
Between 1983 and 1991 we performed 212 endopyelotomies on 110 cases of primary 102 secondary obstruction the ureteropelvic junction. Of 189 patients in series 89% have been followed for a minimum 6 months postoperatively, 63% more than 3 years (3 to 8-year followup). Our overall success rate has 86% with little difference being detected between that obtained obstructions (85% versus 86%). Other variables, such as patient age, sex or side obstruction, bearing outcome procedure. Endopyelotomy...
No AccessJournal of Urology1 Jan 1986Percutaneous Surgery for Ureteropelvic Junction Obstruction (Endopyelotomy): Technique and Early Results Gopal Badlani, Majid Eshghi, Arthur D. Smith BadlaniGopal Badlani , EshghiMajid Eshghi SmithArthur View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)45503-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We incised ureteropelvic junction obstruction in 31 patients with...
We report 5-year safety and efficacy outcomes of the Aquablation procedure for treatment men with symptomatic benign prostatic hyperplasia large-volume prostate glands.A total 101 moderate to severe symptoms volumes between 80 150 mL underwent a robotic-assisted in prospective multicenter international trial (NCT03123250). Herein we final results.The study successfully met its performance goal, which was based upon transurethral resection typically done smaller prostates, at 3 months. Mean...
Intrinsic sphincter deficiency (ISD) is frequently treated with collagen bulking at the bladder neck. The standard material used, Contigen, biodegrades over 3–19 months requiring repeated injections to maintain efficacy. study objective was evaluate use of autologous ear chondrocytes for treatment ISD. Women documented ISD had harvest auricular cartilage. Chondrocytes were isolated from cartilage and expanded in culture formulated calcium alginate form an injectable gel. Thirty-two patients...
We compared the results of first 56 consecutive percutaneous corrections ureteropelvic junction obstruction (endopyelotomy) at our institution with most recent 32 cases open pyeloplasty. The procedure required less time (average 89.4 minutes versus 106.4 for an operation) and entailed postoperative pain (60 per cent patients average 4.7 unit doses narcotics, whereas 88 pyeloplasty 10.3 doses). hospital stay was after endopyelotomy 6.2 10.0 days) return to normal activity occurred more...
We evaluated the effects of an acute cerebrovascular accident on lower urinary tract and correlated site with findings urodynamic study.A total 45 men 15 women underwent a complete study electromyography within 72 hours accident. Patients were divided into 5 different groups based findings.The majority cortical internal capsule lesions resulted in detrusor hyperreflexia. A 28 patients (47%) had retention, mainly due to areflexia (75%). Of 20 hemorrhagic infarcts 17 (85%) areflexia, compared...
To present early safety and feasibility data from a multicentre prospective study (WATER II) of aquablation in the treatment symptomatic men with large-volume benign prostatic hyperplasia (BPH).Between September December 2017, 101 moderate-to-severe BPH symptoms prostate volume 80-150 mL underwent international clinical trial. Baseline demographics standardized postoperative management variables were carefully recorded central independently monitored database. Surgeons answered analogue...
Cell therapy for intrinsic urinary sphincter deficiency (ISD) in women has been moderately effective, and improvements are needed. To improve treatment efficacy, it is important to better understand determinates of cell efficacy the different patient cohorts. We have reported that nonhuman primates chronicity ISD may affect but additional factors (age, psychosocial stress, hormone status, body weight) can be associated with many disease/treatment outcomes – these focus this study. Adult...
Post-prostatectomy incontinence in patients with cancer of the prostate is often result sphincteric injury. However, recent studies have emphasized role detrusor instability and decreased bladder compliance etiology post-prostatectomy incontinence. To further clarify primary cause incontinence, we reviewed urodynamic 39 referred for evaluation after prostatectomy (35 radical, 4 TURP radiation) prostrate cancer. Multichannel videourodynamic were performed to characterize function, was...
No AccessJournal of Urology1 Sep 1988Complications Endopyelotomy: Analysis in Series 64 Patients Gopal Badlani, Gary Karlin, and Arthur D. Smith BadlaniGopal Badlani , KarlinGary Karlin SmithArthur View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)41694-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We review the complications failures our first patients who underwent endopyelotomy. There were 2...
Interstitial cystitis and bladder pain syndrome are terms used to describe a heterogeneous chronic pelvic disorder. Despite its significant prevalence, our understanding of disease etiology is poor. We molecularly characterized interstitial cystitis/bladder determined whether there clinical factors that correlate with gene expression.Bladder biopsies from female subjects controls without signs the were collected divided into those normal low anesthetized capacity, respectively. Samples then...
To present 6-month safety and effectiveness data from a multicentre prospective study of aquablation in men with lower urinary tract symptoms (LUTS) attributable to benign prostatic hyperplasia (BPH) prostate volumes between 80 150 mL.Between September December 2017, 101 LUTSattributable BPHwere prospectively enrolled at 16 centres Canada the USA.The mean volume was 107 mL. The length hospital stay after procedure 1.6 days (range: same day 6 days). primary endpoint (Clavien-Dindo grade 2 or...
To report 12-month safety and effectiveness outcomes of the Aquablation procedure for treatment men with symptomatic benign prostatic hyperplasia (BPH) large-volume prostates.One hundred one moderate-to-severe BPH symptoms prostate volumes 80-150 cc underwent a robotic-assisted in prospective multicenter international clinical trial. Functional were assessed at 12 months postoperatively.Mean volume was 107 (range 80-150). Mean operative time 37 minutes mean resection 8 minutes. The average...
To compare 2-year safety and efficacy outcomes after Aquablation or transurethral resection of the prostate (TURP) for treatment lower urinary tract symptoms related to benign hyperplasia (BPH). One hundred eighty-one patients with BPH were assigned at random (2:1 ratio) either TURP. Patients follow-up assessors blinded treatment. Assessments included International Prostate Symptom Score (IPSS), Male Sexual Health Questionnaire (MSHQ), Index Erectile Function uroflow. The focus analysis was...
This study aimed to determine if local injection of CXCL12 reduces sphincter fibrosis, restores muscle content, vascularization, and innervation, recruits progenitor cells in a rabbit model anal injury incontinence. Adult female rabbits were assigned 3 groups: uninjured/no treatment (control), injured/treated (treated), injured/no (untreated) (n=4 each). Injured groups anesthetized section external was removed at the 9:00 o’clock position. The treated sphincters injected with 200ng human...
Void spot assay (VSA) noninvasively evaluates urination. VSA is often not performed in rats due to difficulty analyzing larger papers compared with mouse. This study optimizes for by comparing post-assay visualization techniques: bright field light (BF), ultraviolet (UV), and ninhydrin spray (N). Male were placed cages lined filter paper 4 hours. Water food was provided ad lib. After the all dried overnight. BF images photographed (digital camera). UV captured after cutting half using a...