A5025893332- Eating Disorders and Behaviors
- Obsessive-Compulsive Spectrum Disorders
- Obesity, Physical Activity, Diet
- Impact of Technology on Adolescents
- Child Nutrition and Feeding Issues
- Body Image and Dysmorphia Studies
- Regulation of Appetite and Obesity
- Behavioral Health and Interventions
- Biochemical Analysis and Sensing Techniques
- Evolutionary Psychology and Human Behavior
- Neurotransmitter Receptor Influence on Behavior
- Transcranial Magnetic Stimulation Studies
- Diet and metabolism studies
- Functional Brain Connectivity Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neurological disorders and treatments
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health Research Topics
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Aesthetic Perception and Analysis
- Bariatric Surgery and Outcomes
- Child Development and Digital Technology
- Workaholism, burnout, and well-being
- Psychotherapy Techniques and Applications
Stanford University
2015-2025
State Street (United States)
2024
Stanford Health Care
2022-2023
Rutgers, The State University of New Jersey
2021
New York University
2021
Oxford University Press (United Kingdom)
2020
University of California, Los Angeles
2010-2012
Neurobehavioral Systems
2012
University of Oregon
2008-2010
Oregon Research Institute
2007-2010
The dorsal striatum plays a role in consummatory food reward, and striatal dopamine receptors are reduced obese individuals, relative to lean which suggests that the dopaminergic signaling may contribute development of obesity. Thus, we tested whether activation response intake is related current future increases body mass these relations moderated by presence A1 allele TaqIA restriction fragment length polymorphism, associated with D2 receptor (DRD2) gene binding compromised signaling....
The authors tested the hypothesis that obese individuals experience greater reward from food consumption (consummatory reward) and anticipated (anticipatory than lean using functional magnetic resonance imaging (fMRI) with 33 adolescent girls (mean age = 15.7, SD 0.9). Obese relative to showed activation bilaterally in gustatory cortex (anterior mid insula, frontal operculum) somatosensory regions (parietal operculum Rolandic response intake of chocolate milkshake (vs. a tasteless solution)...
The authors examined the reciprocal relations between rumination and symptoms of depression, bulimia, substance abuse with longitudinal data from 496 female adolescents. Rumination predicted future increases in bulimic symptoms, as well onset major binge eating, abuse. Depressive bulimic, but not abuse, rumination. did predict externalizing providing evidence for specificity effects rumination, although Results suggest may contribute to etiology depressive, pathology that former two...
Consistent with the theory that individuals hypofunctioning reward circuitry overeat to compensate for a deficit, obese versus lean humans have fewer striatal D2 receptors and show less response palatable food intake. Low intake predicts future weight gain in those at genetic risk reduced signaling of dopamine-based circuitry. Yet animal studies indicate results downregulation receptors, sensitivity, decreased implying overeating may contribute responsivity. Thus, we tested whether leads...
Abstract Objective: To test the hypothesis that women with full and subthreshold bulimia nervosa show abnormal neural activation in response to food intake anticipated relative healthy control women. Method: Females without full/subthreshold recruited from community ( N = 26) underwent functional magnetic resonance imaging (fMRI) during receipt of chocolate milkshake a tasteless solution. Results: Women showed trends for less than controls right anterior insula (vs. solution) left middle...
The necessity to employ distance-based methods deliver on-going eating disorder care due the novel coronavirus (COVID-19) pandemic represents a dramatic and urgent shift in treatment delivery. Yet, TeleHealth treatments for disorders youth have not been adequately researched or rigorously tested. Based on clinical experience within our clinic research programs, we aim highlight common challenges clinicians may encounter providing family-based (FBT) via children adolescents with anorexia...
Abstract Cravings that precede loss of control (LOC) over food consumption present an opportunity for intervention in patients with the binge eating disorder (BED). In this pilot study, we used responsive deep brain stimulation (DBS) to record nucleus accumbens (NAc) electrophysiology during cravings preceding LOC two BED and severe obesity (trial registration no. NCT03868670). Increased NAc low-frequency oscillations, prominent cravings, were guide DBS delivery. Over 6 months, observed...
Abstract Objective: To test the hypothesis that emotional eaters show greater neural activation in response to food intake and anticipated than nonemotional whether these differences are amplified during a negative versus neutral mood state. Method: Female ( N = 21) underwent functional magnetic resonance imaging (fMRI) receipt of chocolate milkshake tasteless control solution while mood. Results: Emotional showed parahippocampal gyrus anterior cingulate (ACC) pallidum, thalamus, ACC...
Background Anorexia nervosa (AN) and body dysmorphic disorder (BDD) are characterized by distorted image frequently co-morbid with each other, although their relationship remains little studied. While there is evidence of abnormalities in visual visuospatial processing both disorders, no study has directly compared the two. We used two complementary modalities – event-related potentials (ERPs) functional magnetic resonance imaging (fMRI) to test for abnormal activity associated early...
Barriers limit access to eating disorder treatment. Evidence-based treatment delivered using telemedicine could expand access. This study determined the effectiveness of enhanced Family-Based Treatment (FBT+) for children and adolescents with disorders. Participants had a confirmed diagnosis, lived in states where was available, family member willing participate. Virtual FBT+ administered by five-person team including therapist, dietitian, medical provider, peer mentor, mentor up 12 months....
Abstract Only recently have more specific circuit-probing techniques become available to inform previous reports implicating the rodent hippocampus in orexigenic appetitive processing 1–4 . This function has been reported be mediated at least part by lateral hypothalamic inputs, including those involving neuropeptides, such as melanin-concentrating hormone 5,6 circuit, however, remains elusive humans. Here we combine tractography, intracranial electrophysiology, cortico-subcortical evoked...
Cranial electrotherapy stimulation (CES) is a U.S. Food and Drug Administration (FDA)-approved treatment for insomnia, depression, anxiety consisting of pulsed, low-intensity current applied to the earlobes or scalp. Despite empirical evidence clinical efficacy, its mechanism action largely unknown. The goal was characterize acute effects CES on resting state brain activity. Our primary hypothesis that would result in deactivation cortical subcortical regions. Eleven healthy controls were...
Atypical anorexia nervosa (AAN) is an eating disorder that shares all symptoms with (AN) except "significantly low weight." Here, we aim to further understand the potential similarities and differences between AN AAN in a clinical sample of patients receiving family-based treatment (FBT) for or AAN. The objectives this study were 1) compare presentations among adolescent young adult AAN; (2) evaluate response FBT these patients. Clinical data from 1,438 (M = 15.3 years, SD 2.51) undergoing...
Food-related cognitive reappraisal refers to reinterpreting thoughts about eating and can be used downregulate the desire eat. Food has been proposed as a method for treating obesity overweight. However, influence of food on affective states understudied. The present study examined role played by negative affect in effects reappraisal. Two experiments were conducted, each included 40 healthy participants. In Experiment 1, participants engaged dual task that combined with an emotion picture...
Several researchers who have evaluated Interpersonal Psychotherapy (IPT) wrote a commentary arguing that the group-delivered IPT treatment for eating disorders we adapted and used in recent trial (Stice, Rohde, et al., 2023) was less effective than new dissonance-based disorder (Body Project Treatment) because did not contain all core elements, developmentally appropriate, tailored people with disorders, our team lacked sufficient expertise. In response, note produced higher abstinence from...