Kristin Gravdal

ORCID: 0000-0001-9982-2503
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About
Contact & Profiles
Research Areas
  • Gut microbiota and health
  • Colorectal Cancer Screening and Detection
  • Clostridium difficile and Clostridium perfringens research
  • Complementary and Alternative Medicine Studies
  • Nutritional Studies and Diet
  • Helicobacter pylori-related gastroenterology studies
  • Gastrointestinal motility and disorders
  • Medical and Biological Ozone Research
  • Therapeutic Uses of Natural Elements

Genetic Analysis (Norway)
2022-2024

Compared to their healthy counterparts, patients with type 2 diabetes (T2D) can exhibit an altered gut microbiota composition, correlated detrimental outcomes, including reduced insulin sensitivity, dyslipidemia, and increased markers of inflammation. However, a typical T2D profile is not established. The aim this pilot study was explore the bacteria associated prediabetes (pre-T2D) patients, treatment naïve compared subjects.Fecal samples were collected from subjects (from Norway)....

10.1186/s12902-023-01432-0 article EN cc-by BMC Endocrine Disorders 2023-08-21

Background and Aims: The mineral compound Luvos Healing Earth (LHE) is a commercially available remedy empirically used for variety of gastrointestinal disorders. aim this study was to investigate the possible effect prolonged LHE therapy on gut microbiota in healthy individuals patients with diarrhea-predominant irritable bowel syndrome (IBS-D). Methods: In prospective exploratory study, total 20 participants, including 12 controls 8 IBS-D, received treatment (Magenfein Granulat, 1 sachet...

10.15403/jgld-5309 article EN Journal of Gastrointestinal and Liver Diseases 2024-03-29

Introduction: There are numerous confounding variables in the pre-analytical steps analysis of gut microbial composition that affect data consistency and reproducibility. This study compared two DNA extraction methods from same faecal samples to analyse differences composition. Methods: was extracted 20 using either (A) chemical/enzymatic heat lysis (lysis buffer, proteinase K, 95 °C + 70 °C) or (B) mechanical (bead-beating, 65 °C). Gut microbiota mapped through 16S rRNA gene (V3–V9) a set...

10.3390/genes13061069 article EN Genes 2022-06-15

<h3>Background</h3> Next-generation sequencing (NGS) has revolutionised genomics research and become increasingly cost-effective. However, there are numerous confounding variables that affect data consistency reproducibility, particularly in the pre-analytical steps. This study compared two DNA extraction methods from same faecal samples to analyse differences microbial composition. <h3>Methods</h3> Faecal were collected twenty patients at Royal Wolverhampton NHS Trust, UK. was extracted...

10.1136/gutjnl-2022-bsg.293 article EN Poster presentations 2022-06-01
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