A5044276813- Cold Atom Physics and Bose-Einstein Condensates
- Atomic and Subatomic Physics Research
- Cell Image Analysis Techniques
- Quantum, superfluid, helium dynamics
- Cellular Mechanics and Interactions
- Image Processing Techniques and Applications
- Strong Light-Matter Interactions
- Spectroscopy Techniques in Biomedical and Chemical Research
- Quantum optics and atomic interactions
- Force Microscopy Techniques and Applications
- Digital Imaging for Blood Diseases
- Optical Coherence Tomography Applications
- Elasticity and Material Modeling
- Quantum and electron transport phenomena
- Advanced Thermodynamic Systems and Engines
- Advanced X-ray Imaging Techniques
- Non-Invasive Vital Sign Monitoring
- Nonlinear Dynamics and Pattern Formation
- Advanced X-ray and CT Imaging
- Microfluidic and Bio-sensing Technologies
- Context-Aware Activity Recognition Systems
- Photoacoustic and Ultrasonic Imaging
- Neural and Behavioral Psychology Studies
- Radiomics and Machine Learning in Medical Imaging
- Malaria Research and Control
Wellcome / EPSRC Centre for Interventional and Surgical Sciences
2019-2023
University College London
2018-2023
Faculty (United Kingdom)
2020
National Physical Laboratory
2015-2018
Imperial College London
2016
Simon Fraser University
2010-2011
Abstract Over 200 million malaria cases globally lead to half a deaths annually. Accurate diagnosis remains challenge. Automated imaging processing approaches analyze Thick Blood Films (TBF) could provide scalable solutions, for urban healthcare providers in the holoendemic sub‐Saharan region. Although several have been attempted identify parasites TBF, none achieved negative and positive predictive performance suitable clinical use west While parasite object detection an intermediary step...
We report on the observation of quantum coherence Bose–Einstein condensed photons in an optically pumped, dye-filled microcavity. find that is long-range space and time above condensation threshold, but short-range below compatible with thermal-equilibrium theory. Far condensate no longer at thermal equilibrium fragmented over non-degenerate, spatially overlapping modes. A microscopic theory including cavity loss, molecular structure relaxation shows this multimode similar to lasing induced...
Digitization of pathology has been proposed as an essential mitigation strategy for the severe staffing crisis facing most departments. Despite its benefits, several barriers have prevented widespread adoption digital workflows, including cost and pathologist reluctance due to subjective image quality concerns. In this work, we quantitatively determine minimum requirements binary classification histopathology images breast tissue in terms spatial sampling resolution. We train ensemble deep...
Automated digital high-magnification optical microscopy is key to accelerating biology research and improving pathology clinical pathways. High magnification objectives with large numerical apertures are usually preferred resolve the fine structural details of biological samples, but they have a very limited depth-of-field. Depending on thickness sample, analysis specimens typically requires acquisition multiple images at different focal planes for each field-of-view, followed by fusion...
Extracellular protein matrices provide a rigidity interface exhibiting nano-mechanical cues that guide cell growth and proliferation. Cells sense such using actin-rich filopodia extensions which encourage favourable cell–matrix contacts to recruit more actin-mediated local forces into forming stable focal adhesions. A challenge remains in identifying measuring these cellular establishing empirical relationships between them, adhesion formation. Here we investigate micromanipulation system...
We demonstrate a technique for exciting spin waves in an ultracold gas of Rb-87 atoms based on tunable AC Stark potentials. This allows us to excite normal modes with arbitrary amplitudes the trapped gas, including dipole, quadrupole, octupole, and hexadecapole modes. These exhibit strong nonlinearities, which manifest as amplitude dependence excitation frequencies departure from sinusoidal behavior. Our results are good agreement full treatment quantum Boltzmann transport equation.
Abstract Abrupt increases of sensory input (onsets) likely reflect the occurrence novel events or objects in environment, potentially requiring immediate behavioral responses. Accordingly, onsets elicit a transient and widespread modulation ongoing electrocortical activity: Vertex Potential (VP), which is related to optimisation rapid In contrast, functional significance brain response elicited by abrupt decreases (offsets) more elusive, detailed comparison onset offset VPs lacking. four...
Fast accurate diagnosis of malaria is still a global health challenge for which automated digital-pathology approaches could provide scalable solutions amenable to be deployed in low-to-middle income countries. Here we address the problem Extended Depth-of-Field (EDoF) thick blood film microscopy rapid diagnosis. High magnification oil-objectives (100x) with large numerical aperture are usually preferred resolve fine structural details that help separate true parasites from distractors....
We study the collapse and revival of coherence induced by dipolar spin waves in a trapped gas $^{87}\mathrm{Rb}$ atoms. In particular, we observe spatially localized Ramsey fringe contrast show how pattern depends on strength spin-wave excitation. find that spatial character dynamics is incompatible with simple model based only position-space overlap wave functions. this phenomenon requires full phase-space description atomic using quantum Boltzmann transport equation, which highlights...
We describe a prototype calibration system for the Traceable Radiometry Underpinning Terrestrial- and Helio-Studies (TRUTHS) satellite mission. outline design testing of key components, including Cryogenic Solar Absolute Radiometer (CSAR). CSAR is designed to make Total Irradiance (TSI) measurements with standard uncertainty < 0.01 % provide SI-traceable hyperspectral Earth imager (EI) over wavelength range 320 nm – 2450 nm. The EI Spectral (SSI) spectral radiance 0.3 %.
Intraoperative frozen section analysis can be used to improve the accuracy of tumour margin estimation during cancer resection surgery through rapid processing and pathological assessment excised tissue. Its applicability is limited in some cases due additional risks associated with prolonged surgery, largely from time-consuming staining procedure. Our work uses a measurable property bulk tissue bypass process: as cells proliferate, they influence surrounding extra-cellular matrix, resulting...
We propose a novel, device-less, battery-less and simple to install localization system for tracking of people in indoors environment. It is based on the capacitive coupling principle, where presence person between electrodes induces variation capacitance. This method can be used most standard applications including home monitoring, activity or even fall detection. does not require subjects carry any devices entire easily concealed order interfere with daily activities users. An electrical...
Structural and mechanical differences between cancerous healthy tissue give rise to variations in macroscopic properties such as visual appearance elastic modulus that show promise signatures for early cancer detection. Atomic force microscopy (AFM) has been used measure significant stiffness cells owing its high sensitivity spatial resolution, however due absorption scattering of light, it is often challenging accurately locate where AFM measurements have made on a bulk sample. In this...