Grace Salacup

ORCID: 0000-0002-0003-2040
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Acute Kidney Injury Research
  • COVID-19 and healthcare impacts
  • Intensive Care Unit Cognitive Disorders
  • Heart Failure Treatment and Management
  • Atrial Fibrillation Management and Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Liver Disease Diagnosis and Treatment
  • Restraint-Related Deaths
  • Inflammatory Biomarkers in Disease Prognosis
  • Renal and Vascular Pathologies
  • Palliative Care and End-of-Life Issues
  • Vitamin C and Antioxidants Research
  • Vascular Tumors and Angiosarcomas
  • Mitochondrial Function and Pathology
  • Mechanical Circulatory Support Devices
  • Aortic Disease and Treatment Approaches
  • Systemic Lupus Erythematosus Research
  • Immunodeficiency and Autoimmune Disorders
  • Medical Imaging and Pathology Studies
  • Antibiotic Use and Resistance
  • Pleural and Pulmonary Diseases
  • Potassium and Related Disorders
  • Ectopic Pregnancy Diagnosis and Management

Einstein Medical Center Philadelphia
2020-2023

Grace (United States)
2021

Bacterial coinfection is associated with poor outcomes in patients viral pneumonia, but data on its role the mortality of coronavirus disease 2019 (COVID-19) limited. This a single-center retrospective analysis 242 confirmed COVID-19 admitted to both intensive care and non-intensive settings. was determined by presence characteristic clinical features positive culture results. Multivariable logistic regression used analyze association concomitant bacterial infection inpatient death after...

10.1002/jmv.26441 article EN Journal of Medical Virology 2020-08-28

There is no current standardized approach to anticoagulation in patients with Coronavirus Disease 2019 (COVID-19) while potential bleeding risks remain. Our study characterizes the patterns of use COVID-19 and risk related bleeding.

10.1016/j.thromres.2020.08.035 article EN other-oa Thrombosis Research 2020-08-24

<b><i>Introduction:</i></b> Emerging data have described poor clinical outcomes from infection with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) among African American patients and those underserved socioeconomic groups. We sought to describe characteristics of kidney injury (AKI) in this special population. <b><i>Methods:</i></b> This is a retrospective study conducted an area predominance disease 2019 (COVID-19)....

10.1159/000509182 article EN other-oa Cardiorenal Medicine 2020-01-01

Abstract There is limited information describing the characteristics and clinical outcomes of patients infected with coronavirus disease 2019 (COVID‐19) especially those in underserved urban area minority population United States. This a retrospective single‐center study for who were admitted COVID‐19 infection. Data collection was from 1 March through 24 April 2020. Demographic, clinical, laboratory, treatment data presented using descriptive statistics frequencies. The χ 2 test...

10.1002/jmv.26252 article EN Journal of Medical Virology 2020-07-03

Coronavirus disease 19 (COVID-19) has become a pandemic. Diabetic patients tend to have poorer outcomes and more severe (Kumar et al. in Diabetes Metab Syndr 14(4):535-545, 2020. https://doi.org/10.1016/j.dsx.2020.04.044 ). However, the vast majority of studies are representative Asian Caucasian population fewer represent an African-American population.In this single-center, retrospective observational study, we included all adult (> 18 years old) admitted Einstein Medical Center,...

10.1007/s00592-020-01592-8 article EN other-oa Acta Diabetologica 2020-08-17

A lot remains unknown about the features and laboratory findings that may predict worse outcomes in patients with coronavirus disease 2019 (COVID-19). The aim of this study was to evaluate difference complete blood count parameters differential counts hospitalized COVID-19 who survived compared those died.We performed a single-center retrospective including 242 confirmed COVID-19. We described characteristics these patients. Mann-Whitney U test used compare hematologic died survived;...

10.1111/ejh.13509 article EN European Journal Of Haematology 2020-08-14

Recent studies have reported evidence that coronavirus disease 2019 (COVID-19) has disproportionately affected patients with underlying comorbidities. Our study aims to evaluate the impact of both cardiac and noncardiac comorbidities on a high-risk population COVID-19 infection coronary artery (CAD) compared those without CAD.This is retrospective who tested positive via reverse transcriptase-PCR (RT-PCR) assay. We characteristics outcomes CAD. Population demographics, clinical were...

10.1097/mca.0000000000000934 article EN Coronary Artery Disease 2020-07-23

Abstract Identify factors associated with readmission after an index hospital admission for coronavirus disease 2019 (COVID‐19) infection in a single center serving underserved and predominantly minority population. This retrospective descriptive study included 275 patients who tested COVID‐19 positive via reverse transcriptase‐polymerase chain reaction assay at our institution survived the hospitalization. The main outcomes were 1‐ 6‐month rates hospitalization COVID‐19. mortality rate...

10.1002/jmv.27104 article EN Journal of Medical Virology 2021-05-27

The rapidly expanding cases of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) have exposed vulnerable populations, including pregnant women to an unprecedented public health crisis. Recent data show that pregnancy in COVID-19 patients is associated with increased hospitalization, admission intensive care unit, and intubation. However, very few resources exist guide multidisciplinary team managing critically ill COVID-19. We report our...

10.1155/2020/8889487 article EN cc-by Case Reports in Critical Care 2020-10-14

<b><i>Background:</i></b> Determination of adequacy decongestion remains a significant challenge in the management acute heart failure (AHF). <b><i>Methods:</i></b> This is prospective single center cohort study patients (>18 years old) admitted for AHF on intravenous diuretics, with BNP >100 pg/mL or echocardiographic findings reduced ejection fraction diastolic dysfunction, and at least 1 clinical sign volume overload....

10.1159/000525730 article EN cc-by-nc Cardiorenal Medicine 2022-01-01

There are limited data regarding the use of angiotensin converting enzyme inhibitors/angiotensin receptor blockers (ACEi/ARBs) in acute heart failure (AHF). The purpose is to determine patterns ACEi/ARB at time admission and discharge relation invasive hemodynamic data, mortality, (HF) readmissions. This a retrospective single-center study patients with AHF who underwent right catheterization between January 2010 December 2016. Patients on dialysis, evidence shock, or incomplete follow up...

10.31083/j.rcm.2021.01.216 article EN cc-by Reviews in Cardiovascular Medicine 2021-01-01

Venous thromboembolism (VTE) is reported in up to 27% of patients with COVID-19 due SARS-CoV-2 infection. Dysregulated systemic inflammation and various patient traits are presumed underlie this anomaly. Optimal VTE prophylaxis has not been established a lack validated models for predicting population. Our study aims address deficiency by identifying demographic clinical characteristics associated increased risk.This retrospective analysis all adult (final sample, n = 355) hospitalized...

10.1111/crj.13377 article EN The Clinical Respiratory Journal 2021-04-17

10.1016/s0735-1097(20)33943-7 article EN publisher-specific-oa Journal of the American College of Cardiology 2020-03-01

A 28-year-old Southeast Asian non-pregnant woman with asthma and prior cholecystectomy presented to the emergency department acute watery diarrhoea, intermittent abdominal pain vomiting. Apart from tenderness, rest of physical examination was unremarkable. She had leucocytosis, alkaline phosphatase elevation exudative ascites. Radiological imaging ruled out biliary leak only significant for circumferential small large bowel thickening. Upper endoscopy colonoscopy showed normal duodenal...

10.1136/bcr-2020-239072 article EN BMJ Case Reports 2021-08-01

10.1016/s0735-1097(20)34019-5 article EN publisher-specific-oa Journal of the American College of Cardiology 2020-03-01

10.1016/s0735-1097(20)34052-3 article EN publisher-specific-oa Journal of the American College of Cardiology 2020-03-01

INTRODUCTION: Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) is now a critical threat to global public health. Although, the majority of patients present with illness, several studies have described multi-organ involvement. The purpose this study was report liver enzyme test results in COVID-19 on admission and their association clinical outcomes. METHODS: This single-center retrospective analysis all in-patients confirmed diagnosis...

10.14309/01.ajg.0000715036.58966.1b article EN The American Journal of Gastroenterology 2020-10-01

Background: Hepatorenal syndrome (HRS), a form of kidney dysfunction frequent in cirrhotic patients, is characterized by low filling pressures and impaired perfusion due to peripheral vasodilation reduced effective circulatory volume. Cardiorenal (CRS), driven renal venous hypertension elevated pressures, separate cause patients. The two entities, however, have similar clinical phenotypes. To date, limited invasive hemodynamic data are available help distinguish the primary forces behind...

10.2139/ssrn.4091294 article EN SSRN Electronic Journal 2022-01-01

Introduction: The utility of serum and urine osmolality in evaluating decongestion outcomes heart failure (HF) remain understudied. Methods: This is a prospective cohort single center study patients with acute HF on intravenous diuretics > 18 years old, BNP 100 pg/mL or echocardiographic finding reduced ejection fraction diastolic dysfunction, at least 1 symptom volume overload. Patients eGFR≤45mL/minute dialysis, exposure to contrast dye nephrotoxins were excluded. Serum obtained daily...

10.1161/circ.144.suppl_1.9408 article EN Circulation 2021-11-16
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