A5080348752- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Animal Nutrition and Physiology
- Mycobacterium research and diagnosis
- Ginseng Biological Effects and Applications
- Microbial Metabolic Engineering and Bioproduction
- Milk Quality and Mastitis in Dairy Cows
- CRISPR and Genetic Engineering
- Osteoarthritis Treatment and Mechanisms
- Reproductive Biology and Fertility
- Metabolomics and Mass Spectrometry Studies
- Animal Genetics and Reproduction
- Meat and Animal Product Quality
- Cytokine Signaling Pathways and Interactions
- Reproductive Physiology in Livestock
- Aquaculture Nutrition and Growth
- Bone Metabolism and Diseases
University of Tehran
2018-2025
Kurdistan University of Medical Sciences
2021
Understanding the molecular pattern of fertility is considered as an important step in breeding different species, and despite high importance fertility, little success has been achieved dissecting interactome basis sheep fertility. However, complex mechanisms associated with prolificacy have not fully understood. Therefore, this study aimed to use competitive endogenous RNA (ceRNA) networks evaluate trait better understand responsible for A network corpus luteum was constructed between...
Intramuscular fat content (IMF), one of the most important carcass traits in beef cattle, is controlled by complex regulatory factors. At present, molecular mechanisms involved regulating IMF and metabolism cattle are not well understood. Our objective was to integrate comparative transcriptomic competing endogenous RNA (ceRNA) network analyses identify candidate messenger RNAs (mRNAs) regulation longissimus dorsi muscle (LDM) tissue for 5 breeds (Angus, Chinese Simmental, Luxi, Nanyang,...
Background: There is growing interest in the genetic improvement of fertility traits female goats. With high-throughput genotyping, single-cell RNA sequencing (scRNA-seq) a powerful tool for measuring gene expression profiles. The primary objective was to investigate comparative transcriptome profiling granulosa cells (GCs) high- and low-fertility goats, using scRNA-seq. Methods: Thirty samples from Ji'ning Gray goats (n = 15 high n low fertility) were retrieved publicly available scRNA-seq...
Fatty acid metabolism in poultry has a major impact on production and disease resistance traits. According to the high rate of interactions between lipid its regulating properties, holistic approach is necessary. To study omics multilayers adipose tissue identification genes miRNAs involved fat metabolism, storage endocrine signaling pathways two groups broiler chickens with low abdominal fat, as well high-throughput techniques, were used. The gene-miRNA interacting bipartite...
Abstract Aim Osteoarthritis (OA) is the most common chronic joint disorder, resulting from breakdown of cartilage. It occurs in knees, hands, and hips, leading to pain, stiffness, inflammation, swelling. Methods In this study, 100 hand knee OA patients, meeting American College Rheumatology criteria were included case group, healthy individuals allocated control group. Blood samples collected participants. After DNA extraction, genotyping was carried out for GDF5 rs143383 C/T polymorphism by...
This manuscript summarizes information on the diverse range of RNA molecules and their role as competing endogenous RNAs (ceRNAs). Moreover, it provides an overview ceRNA regulatory networks applications in ruminant biology. Knowledge co-expression has increased with microarrays, RNA-seq, scRNA-seq characterizing molecular mediators across various biological scales, using sequences from numerous blood tissue samples. By synthesizing existing knowledge, this study interactions between coding...
Paratuberculosis or Johne’s disease (JD), a chronic granulomatous gastroenteritis caused by Mycobacterium avium subsp. paratuberculosis (MAP), causes huge economic losses and reduces animal welfare in dairy cattle herds worldwide. At present, molecular mechanisms biological functions involved immune responses to MAP infection of are not clearly understood. Our purpose was integrate transcriptomic profiles competing endogenous RNA (ceRNA) network analyses identify key messenger RNAs (mRNAs)...
Abstract Background Fatty acid metabolism in animals has a major impact on production and disease resistance traits. According to the high rate of interactions between lipid its regulating properties, holistic approach is necessary. Methods To study multi-omics layers adipose tissue identification genes involved fat metabolism, storage endocrine signaling pathways two groups broiler chickens with low abdominal fat, high-throughput screening (HTS) techniques were used. The Gene-miRNA...