A5000762852- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- Reproductive Biology and Fertility
- Plant Molecular Biology Research
- MicroRNA in disease regulation
- Genomics, phytochemicals, and oxidative stress
- Plant Reproductive Biology
- Peroxisome Proliferator-Activated Receptors
- Genetic Mapping and Diversity in Plants and Animals
- Animal Nutrition and Physiology
- Growth Hormone and Insulin-like Growth Factors
- Bioinformatics and Genomic Networks
- Circular RNAs in diseases
- COVID-19 Clinical Research Studies
- Milk Quality and Mastitis in Dairy Cows
- Meat and Animal Product Quality
- Machine Learning in Bioinformatics
- Psychology of Moral and Emotional Judgment
- SARS-CoV-2 and COVID-19 Research
- IL-33, ST2, and ILC Pathways
- Adipose Tissue and Metabolism
- Experimental Behavioral Economics Studies
- Reproductive Physiology in Livestock
- Tuberculosis Research and Epidemiology
- RNA regulation and disease
University of Tehran
2016-2025
Ludwig-Maximilians-Universität München
2020-2025
LMU Klinikum
2021-2025
Royal Holloway University of London
2021-2025
Max Planck Institute for Human Development
2021-2025
Atomic Energy Organization of Iran
2025
Nuclear Science and Technology Research Institute
2025
University of Tübingen
2023-2024
Rational (Germany)
2021
Zanjan University of Medical Sciences
2013
The question of whether variable risk factors and various nutrients are causally related to inflammatory bowel diseases (IBDs) has remained unanswered so far. Thus, this study investigated genetically predicted play a function in the occurrence diseases, including ulcerative colitis (UC), non-infective (NIC), Crohn’s disease (CD), using Mendelian randomization (MR) analysis. Utilizing data genome-wide association studies (GWASs) with 37 exposure factors, we ran analyses based on up 458,109...
The recent emergence of COVID-19, rapid worldwide spread, and incomplete knowledge molecular mechanisms underlying SARS-CoV-2 infection have limited development therapeutic strategies. Our objective was to systematically investigate regulatory using a combination high throughput RNA-sequencing-based transcriptomics systems biology approaches.
Prescribing, dispensing, availability and affordability of drugs were evaluated in 100 primary health care centres 5 provinces the Islamic Republic Iran using WHO indicators. On average, 92% 12 essential monitored available centre pharmacies 95% prescribed by physician dispensed pharmacy. The stock-out duration was less than 1 month on average. A complete treatment for pneumonia cost only 2% lowest weekly government salary. national average number per prescription 3.4. Prescription...
Understanding the molecular pattern of fertility is considered as an important step in breeding different species, and despite high importance fertility, little success has been achieved dissecting interactome basis sheep fertility. However, complex mechanisms associated with prolificacy have not fully understood. Therefore, this study aimed to use competitive endogenous RNA (ceRNA) networks evaluate trait better understand responsible for A network corpus luteum was constructed between...
Abstract People are keen to exploit cooperative artificial agents for selfish gain. While this phenomenon has been observed in numerous Western societies, we show here that it is absent Japan. We examined people’s willingness cooperate with and humans two classic economic games requiring a choice between self interest mutual benefit. Our participants the United States cooperated significantly less than they did humans, whereas Japan exhibited equivalent levels of cooperation both types...
The authors assessed the efficacy of bromocriptine in nonfluent aphasia after stroke a 16-week, randomized, double-blind, placebo-controlled clinical trial conducted from June 2002 to April 2004. In all 38 patients 4 months treatment, improvement both and placebo treatment groups was observed (<i>p</i> < 0.001). analysis repeated-measures variance revealed did not improve aphasia.
Abstract. Genetic and phenotypic parameters were estimated for lamb growth traits the Shal sheep using an animal model. Data on performance extracted from available records at Station in Qazvin, Iran. Studied body weights of lambs birth (BW), 3 months age as weaning weight (WW), 6 (6MW), 9 (9MW), yearling (YW), average daily gain to (ADG) Kleiber ratio (KR). Significant random effects each trait determined by fitting additive direct genetic effects, maternal covariance between permanent...
In recent years, studies on the biological mechanisms underlying complex traits have been facilitated by innovations in high-throughput genotyping technology. We conducted a weighted single-step genome-wide association study (WssGWAS) to evaluate backfat thickness, carcass weight, eye muscle area, marbling score, and yearling weight cohort of 1540 Hanwoo beef cattle using BovineSNP50 BeadChip. The WssGWAS uncovered thirty-three genomic regions that explained more than 1% additive genetic...
Abstract Nudge is a popular public policy tool that harnesses well-known biases in human judgement to subtly guide people’s decisions, often improve their choices or achieve some socially desirable outcome. Thanks recent developments artificial intelligence (AI) methods new possibilities emerge of how and when our decisions can be nudged. On the one hand, algorithmically personalized nudges have potential vastly daily lives. other blindly outsourcing development implementation “black box” AI...
At later phases of folliculogenesis, the mammalian ovarian follicle contains layers granulosa cells surrounding an antral cavity. To better understand molecular basis follicular growth and cell maturation, we study transcriptome profiling from small (<5 mm) large (>10 bovine follicles using simultaneous method Affymetrix microarrays (24,128 probe sets) RNA-Seq data sets. This proposes a computational to discover functional miRNA–mRNA regulatory modules, that is, groups miRNAs their...
Background: Bovine respiratory disease (BRD) is the most common in beef and dairy cattle industry. BRD a multifactorial resulting from interaction between environmental stressors infectious agents. However, molecular mechanisms underlying are not fully understood yet. Therefore, this study aimed to use systems biology approach systematically evaluate disorder better understand responsible for BRD. Methods: Previously published RNA-seq data whole blood of 18 healthy 25 samples were downloaded...
Background: There is growing interest in the genetic improvement of fertility traits female goats. With high-throughput genotyping, single-cell RNA sequencing (scRNA-seq) a powerful tool for measuring gene expression profiles. The primary objective was to investigate comparative transcriptome profiling granulosa cells (GCs) high- and low-fertility goats, using scRNA-seq. Methods: Thirty samples from Ji'ning Gray goats (n = 15 high n low fertility) were retrieved publicly available scRNA-seq...
Fatty acid metabolism in poultry has a major impact on production and disease resistance traits. According to the high rate of interactions between lipid its regulating properties, holistic approach is necessary. To study omics multilayers adipose tissue identification genes miRNAs involved fat metabolism, storage endocrine signaling pathways two groups broiler chickens with low abdominal fat, as well high-throughput techniques, were used. The gene-miRNA interacting bipartite...