- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- Animal Diversity and Health Studies
- Genetic diversity and population structure
- Livestock and Poultry Management
- Animal Nutrition and Physiology
- Effects of Environmental Stressors on Livestock
- Reproductive Physiology in Livestock
- Livestock Management and Performance Improvement
- Animal Disease Management and Epidemiology
- Rangeland Management and Livestock Ecology
- Animal Genetics and Reproduction
- Agricultural Systems and Practices
- RNA and protein synthesis mechanisms
- Reproductive System and Pregnancy
- CRISPR and Genetic Engineering
- Rabbits: Nutrition, Reproduction, Health
- FOXO transcription factor regulation
- Animal Virus Infections Studies
- Machine Learning in Bioinformatics
- Livestock Farming and Management
- Meat and Animal Product Quality
- Genomics and Phylogenetic Studies
- Antimicrobial Peptides and Activities
Directorate of Poultry Research
2022-2025
National Bureau of Animal Genetic Resources
2014-2024
Jain University
2024
National Dairy Research Institute
2021-2023
Czech Academy of Sciences, Institute of Physiology
2023
Cloud Computing Center
2021
Genome-wide runs of homozygosity (ROH) are suitable for understanding population history, calculating genomic inbreeding, deciphering genetic architecture complex traits and diseases as well identifying genes linked with agro-economic traits. Autozygosity ROH islands, regions elevated frequencies, were characterized in 112 animals seven Indian native cattle breeds (B. indicus) using BovineHD BeadChip. In total, 4138 detected. The average number per animal was maximum draft breed, Kangayam...
Arunachali yak, the only registered yak breed of India, is crucial for economic sustainability pastoralist Monpa community. This study intended to determine genomic diversity and identify signatures selection in breed. Previously available double digest restriction-site associated DNA (ddRAD) sequencing data animals was processed 99,919 SNPs were considered further analysis. The profiled based on nucleotide diversity, π (π = 0.041 200 bp windows), effective population size, Ne (Ne 83) Runs...
The peculiarity of Indian cattle lies in milk quality, resistance to diseases and stressors as well adaptability. investigation addressed selection signatures Gir Tharparkar cattle, belonging arid ecotypes India. Double digest restriction-site associated DNA sequencing (ddRAD-seq) yielded nearly 26 million high-quality reads from unrelated seven cows. In all, 19,127 SNPs were processed for signature analysis. An approach involving within-population composite likelihood ratio (CLR) statistics...
Background: In chickens, female has heterogametic sex chromosomes (ZW) whereas it is homogametic (ZZ) in males. chicken, the can be determined by genes specific to W chromosome. Methods: Ten fertile eggs at18.5th day of incubation were selected for liver tissue sampling and further DNA isolation. The SWIM gene located on chromosome was amplified using primers. Result: PCR results revealed a 212 bp band that birds additionally non- appeared both male at 900 bp. sequencing, alignment BLAST...
Abstract The genomic diversity and relationship among seven diverse cattle breeds viz. Sahiwal, Tharparkar, Gir, Vechur, Ongole, Kangayam Hariana were investigated in 132 random samples based on high density SNP array comprising > 777 K SNPs. A total of 1993 SNPs (0.25% the total) having greater power (F ST ≥ 0.20) to differentiate these populations identified, utilized partition genome each animal into a predefined number clusters. structure indicated shared ancestry dairy Tharparkar...
In total 52 samples of Sahiwal (19 Excoffier L, Laval G, Schneider S. Arlequin 3.01: An integrated software package for population genetics data analysis. Evol Bioinform Online 2005; 1:47–50.[Crossref], [PubMed], [Web Science ®] , [Google Scholar]), Tharparkar (17 Hayes BJ, Bowman PJ, Chamberlain, AJ, Goddard ME. Invited review: genomic selection in dairy cattle: progress and challenges. J Dairy Sci 2009; 92:433–443.[Crossref], Gir (16 Melka HD, Jeon EK, Kim SW, Han JB, Yoon D, KS....
The most polymorphic milk protein gene is β-casein; 13 variants are known in cattle. Milk genetic polymorphism has received considerable research interest recent years because of possible associations between and economically important traits livestock. present study was undertaken to explore the polymorphisms exon 7 β-casein 4 κ-casein genes Arunachali yaks (Bos grunniens), Sahiwal indicus) cattle, malpura sheep (Ovis aries) Gaddi goat (Capra hircus). Results revealed presence 11 SNP all...
Abstract The present study focused upon identification of genome-wide SNPs through the reduced representation approach and to genomic divergence Indian yak populations. A total 80 samples belonging Arunachali (N = 20), Himachali Ladakhi 20) Sikkimi India were used in study. results revealed a 579575 high quality along with 50319 INDELs yaks. observed heterozygosity was found be yak, followed by yaks genetically distant, which have some few individuals from are get clustered together similar....
Summary Molecular markers, viz . microsatellites and single nucleotide polymorphisms, have revolutionized breed identification through the use of small samples biological tissue or germplasm, such as blood, carcass samples, embryos, ova semen, that show no evident phenotype. Classical tools molecular data analysis for limitations, unavailability referral data, causing increased cost collection each time, compromised computational accuracy complexity methodology used. We report here...
Background: Microsatellites are short repeat motifs consisting 1-6 base pair (bp) and have a high degree of length polymorphism useful to study the genetic diversity. In Chicken, no micro satellite markers were demarcated different chromosomes, viz., 29, 34, 35, 36, 37, 38 39 in genome. present study, we carried out chromosome-wise identification SSRs that will be great use diversity gene mapping studies chicken. Methods: The perl script MISA tool was used screen polymorphic microsatellites...
In the present investigation, 618 milk samples of Sirohi breed goat were collected, and analyzed for conjugated linoleic acid (CLA, C18:2) other fatty acids. The CLA in studied was 4.87 mg/g fat C18:2 cis-9, trans-11 contributes 2.9 trans10 cis12 0.82 fat. saturated acids accounted 69.55% unsaturated 28.50%. constituted by monounsaturated (24.57%) polyunsaturated (3.96%.). major contribution (45.56%) total C12:0, C14:0 C16:0. C18:0 short chain ones (C4:0, C6:0, C8:0, C10:0) have a neutral or...
Highland pastoralism provides economic sustainability to the tribal livelihoods and is endemic yak-rearing tracts of India. Transhumant pastoralists Arunachal Pradesh (in India) have centuries-old deep socio-religious connections with this unique bovine species. As a result their conservation efforts, Arunachali was recognized as first still lone breed (to date) yaks in country. A survey conducted on pastoral production system region enable phenotypic characterization understand prevailing...
Yak diversity of the country has remained predominantly unexplored for a long time. Among 169 registered livestock breeds India, sole representation from yak genetic resources is Arunachali yak. This study first time investigated status using 26 bovine microsatellite markers. All markers recommended cattle except one (ILSTS05) amplified with genome. Allelic genotype pattern overlapped between and across 25 loci total 233 alleles were detected in The number observed ranged 3–16 an average...