A5058681904- Genetic and phenotypic traits in livestock
- Microbial infections and disease research
- Mosquito-borne diseases and control
- Cancer-related molecular mechanisms research
- Milk Quality and Mastitis in Dairy Cows
- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- Animal Genetics and Reproduction
- Vector-borne infectious diseases
- MicroRNA in disease regulation
- Genetic Mapping and Diversity in Plants and Animals
- Vector-Borne Animal Diseases
- Genetic diversity and population structure
- interferon and immune responses
- Bat Biology and Ecology Studies
- Animal Virus Infections Studies
- Liver Disease Diagnosis and Treatment
- Aquaculture disease management and microbiota
- Mycobacterium research and diagnosis
- Multiferroics and related materials
- Ferroelectric and Piezoelectric Materials
- Magnetic Properties and Synthesis of Ferrites
- Effects of Environmental Stressors on Livestock
- Rangeland Management and Livestock Ecology
- Plant Virus Research Studies
National Bureau of Animal Genetic Resources
2022-2025
Mahatma Gandhi Central University
2024
Central University of South Bihar
2024
King George's Medical University
1990-2023
Indian Veterinary Research Institute
2003-2022
Indian Council of Agricultural Research
2022
Central Institute for Research on Cattle
2021
Chhatrapati Shahu Ji Maharaj University
2015-2020
All India Institute of Medical Sciences Bhopal
2018
Institute of Medical Sciences
2017
Arunachali yak, the only registered yak breed of India, is crucial for economic sustainability pastoralist Monpa community. This study intended to determine genomic diversity and identify signatures selection in breed. Previously available double digest restriction-site associated DNA (ddRAD) sequencing data animals was processed 99,919 SNPs were considered further analysis. The profiled based on nucleotide diversity, π (π = 0.041 200 bp windows), effective population size, Ne (Ne 83) Runs...
The present study was undertaken to elucidate the population structure and differentiation of Indian yak from Chinese wild cohorts on genome-wide scale by identifying selection sweeps genomic basis their adaptation across different comparisons while analyzing whole genome sequencing (WGS) data using latest bioinformatics tools. included 105 individuals three distinct populations i.e., (n = 29); 61) 15), hypothesized be related along evolutionary timescale. Efficient variant calling quality...
The present study aims to identify genomic variants through a whole genome sequencing (WGS) approach and uncover biological pathways associated with adaptation fitness in Indian yak populations. A total of 30 samples (10 from each population) were included Arunachali, Himachali Ladakhi WGS analysis revealed 32171644, 27260825, 32632460 SNPs 4865254, 4429941, 4847513 Indels the Himachali, yaks, respectively. Genes such as RYR2, SYNE2, BOLA, HF1, novel transcript ENSBGRG00000011079 found have...
The current investigation was undertaken to elucidate the population-stratifying and ancestry-informative markers in Indian, Chinese, wild yak populations using whole genome resequencing (WGS) analysis while employing various selection strategies (Delta, Pairwise Wright's Fixation Index-FST, Informativeness of Assignment) marker densities (5–25 thousand). study used WGS data on 105 individuals from three separate cohorts i.e., Indian (n = 29), Chinese 61), 15). Variant calling GATK program...
Pasteurella multocida causes acute septicemic and respiratory diseases, including haemorrhagic septicaemia, in cattle buffalo with case fatality of 100%. In the present study, mice were infected P. (1.6 × 103 cfu, intraperitoneal) to evaluate host gene expression profile at early late stages infection using high throughput microarray transcriptome analyses. Several differentially expressed genes (DEGs) both time points identified P.multocida spleen, liver lungs. Functional annotation these...
Highly pathogenic Avian influenza (HPAI) is a notifiable viral disease caused by avian type A viruses of the Orthomyxoviridae family. Type genome consists eight segments negative-sense RNA. RNA segment 2 encodes three proteins, PB1, PB1-F2, and N40, which are translated from same mRNA ribosomal leaky scanning reinitiation. Since these proteins critical for replication pathogenesis, targeting their expression can be one approaches to control resist HPAI. MicroRNAs short noncoding RNAs that...
Mastitis is an inflammatory condition of the mammary gland caused by microorganisms as diverse bacteria, viruses, mycoplasma, yeasts and algae.Mastitis economically devastating disease mainly affecting crossbred cattle in India.Control strategies against mastitis includes antibiotic therapy, vaccination, improvements dairy husbandry, farm feeding management etc. but has met with little success.. tolerance/susceptibility difficult to measure directly hence milk somatic cell count (SCC) or...
India is the highest milk producer of world and crossbreeding to augment genetic potential native breeds, has played an important role achieve this feat. The present study with five microsatellite DNA loci BM1818, BM1443, BM1905, BM1258 MB026 associated Somatic Cell Score (SCS) production, was aimed at finding variation in 76 crossbred cows. PCR amplified products were resolved on MetaPhore® agrose. number alleles for found be 7 each while it 8 BM1818. size ranges from 149-186 bp 178-204...
Chilika, a native buffalo breed of the Eastern coast India, is mainly distributed around Chilika brackish water lake connected with Bay Bengal Sea. This possesses unique ability to delve deep into salty and stay there feed on local vegetation saline nature. Adaptation salinity genetic phenomenon; however, basis underlying tolerance still limited in animals, specifically livestock. The present study explores evolution that unveils buffalo's adaptation harsh habitat, including both food...
<title>Abstract</title> This study delves into the genomic foundations of high-altitude adaptation in Indian yaks, with a specific emphasis on X chromosome and its role traits related to production, reproduction, immunity. Utilizing whole-genome resequencing, we identified 319,015 high-quality chromosomal SNPs from 30 unrelated yaks 8 Jinchuan yaks. These were analyzed through various statistical methodologies, including composite likelihood ratio (CLR) statistics, Tajima’s D, iHS,...
To study the major histocompatibility complex (MHC) Class II DRB1 gene polymorphism in Rohilkhandi goat using polymerase chain reaction-restriction fragment length (PCR-RFLP) and nucleotide sequencing techniques.DNA was isolated from 127 goats maintained at sheep farm, Indian Veterinary Research Institute, Izatnagar, Bareilly. A 284 bp of exon 2 amplified digested BsaI TaqI restriction enzymes. Population genetic parameters were calculated Popgene v 1.32 SAS 9.0. The genotypes then sequenced...
Aim:The present study was undertaken to identify whether single nucleotide polymorphism (SNP) rs109231409 located on mannose-binding lectins 1 (MBL1) gene associated with mastitis tolerance/susceptibility. Materials and Methods:After grouping 100 Vrindavani crossbred cattle as positive negative animals, they were genotyped using polymerase chain reaction (PCR)-restriction fragment length polymorphisms method.Gene genotype frequencies of different patterns estimated by standard procedure...