A5081524887- Vector-borne infectious diseases
- Cancer-related molecular mechanisms research
- Vector-Borne Animal Diseases
- MicroRNA in disease regulation
- Genetic and phenotypic traits in livestock
- Effects of Environmental Stressors on Livestock
- Animal Virus Infections Studies
- Animal Disease Management and Epidemiology
- interferon and immune responses
- Animal Genetics and Reproduction
- Wildlife Ecology and Conservation
- Milk Quality and Mastitis in Dairy Cows
- Aquaculture disease management and microbiota
- Viral Infections and Vectors
- Meat and Animal Product Quality
- SARS-CoV-2 and COVID-19 Research
- Insects and Parasite Interactions
- Dermatological diseases and infestations
- Probiotics and Fermented Foods
- Drug Transport and Resistance Mechanisms
- Amphibian and Reptile Biology
- Animal Diversity and Health Studies
- Fish Biology and Ecology Studies
- Parasitic Infections and Diagnostics
- Bat Biology and Ecology Studies
Kerala Veterinary and Animal Sciences University
2020-2024
Indian Veterinary Research Institute
2014-2022
Health & Life (Taiwan)
2021
The Western Ghats, a biodiversity hotspot in peninsular India, serve as critical habitat for the vulnerable Nilgiri langur (Semnopithecus johnii), endemic to region. This study explores phylogenetic placement of S. johnii populations based on mitochondrial CYTB gene (857 bp) sequences. Briefly, twelve faecal samples were collected from three sites within Periyar Tiger Reserve (PTR), Kerala. DNA was isolated and amplified sequenced. sequences subjected analyses using Maximum Likelihood,...
Ticks of the genus Rhipicephalus infesting cattle are primary animal pests responsible for annual economic loss billions dollars. Due to morphological resemblance among members (Boophilus) genus, species identification is very difficult. In this study, adult R. annulatus and microplus ticks from two south Indian states viz., Kerala Karnataka were subjected molecular characterization. The isolates India differed morphologically true clade A ticks. ventral spur on first pedipalp observed in...
Climate change is an imminent threat to livestock production. One adaptation strategy selection for heat tolerance. While it established that the ATP1A1 gene and its product play important role in response many stressors, there has been no attempt characterize sequence or perform expression profiling of production animals. We undertook a field experiment compare profiles heat-tolerant Vechur Kasaragod cattle (Bos taurus indicus) with profile heat-susceptible crossbreed (B. t. × B. indicus)....
Highly pathogenic Avian influenza (HPAI) is a notifiable viral disease caused by avian type A viruses of the Orthomyxoviridae family. Type genome consists eight segments negative-sense RNA. RNA segment 2 encodes three proteins, PB1, PB1-F2, and N40, which are translated from same mRNA ribosomal leaky scanning reinitiation. Since these proteins critical for replication pathogenesis, targeting their expression can be one approaches to control resist HPAI. MicroRNAs short noncoding RNAs that...
India is the highest milk producer of world and crossbreeding to augment genetic potential native breeds, has played an important role achieve this feat. The present study with five microsatellite DNA loci BM1818, BM1443, BM1905, BM1258 MB026 associated Somatic Cell Score (SCS) production, was aimed at finding variation in 76 crossbred cows. PCR amplified products were resolved on MetaPhore® agrose. number alleles for found be 7 each while it 8 BM1818. size ranges from 149-186 bp 178-204...
In spite of increase in milk production, dairy farmers suffer huge economic losses due to mastitis even very well organized and modern farms. It has been observed that with the ability animals become more susceptible mastitis. One most common causes is infection mammary gland caused by bacteria like Staphylococcus aureus Escherichia coli responsible for invoking sub-clinical clinical mastitis, respectively. The resistivity or susceptibility species/breeds towards depends on mode intensity...
The present investigation was performed to compare the global gene expression profile in peripheral blood mononuclear cells (PBMCs) of Bos indicus and crossbred (Bos taurus × B. indicus) cattle. Previously, several studies revealed disease tolerance potential cattle but underlying genetic mechanism is still not fully explored. PBMCs model used for this as it plays crucial role immune system regulation. Transcriptomic analysis total 6767 significantly differentially expressed transcripts...
Abstract An overlap of ranges Nilgiri langurs ( Semnopithecus johnii Fischer, 1829) and tufted gray priam Blyth, 1844) in the Western Ghats resulted formation mixed-species groups (MSGs) with a notable presence brown morphs significant changes group composition population dynamics. Our study investigated MSGs examine vegetation their across Ghats. We identified three new locations Nilgiris southern predominantly found deciduous forests (∼50 %), at an average altitude 621.01 m asl. The mean...
In present study, the polymorphism at five microsatellite loci BM302, BM4505, BMS2684, CYP21 and DIK20 were investigated for finding their association with somatic cell counts (SCC) in crossbred cattle. Total 130 animals tested using california mastitis test (CMT) count to screen mastitis. 83 alleles found all microsatellites where 23 (9 3 2 8 1 DIK20) differing significantly case-control animals. number of genotypes 148, out which 11 The allele size ranges 146 bp 166 bp, 212 252 82 108 180...
Bovine tropical theileriosis is a major haemoprotozoan disease associated with high rates of morbidity and mortality particularly in exotic crossbred cattle. Recent studies suggest that number immune response genes, expressed differentially indigenous breeds play an important role breed specific resistance to theileriosis. In the present study, expression CXCL3 gene which has chemotactic activity for neutrophils, controls migration adhesion monocytes ultimately mediates its effects on target...
The current study was conducted to the diversity analysis of Lactobacilli in naturally fermented ethnic Goan pork sausages as determined by PCR amplification 16-23S rRNA intergenic spacer region and optimal phylogenetic analysis. A total 15 isolates were identified gene sequence Limosilactobacillus fermentum (60%) Lactobacillus rhamnosus (6.66%) brevis predominant lactobacilli found sausages. Phylogenetic showed clustering reference strains same species. results obtained during this will...
In the present study, next generation sequencing was employed to identify and explore differential expression profiles of miRNAs in peripheral blood mononuclear cells (PBMCs) crossbred (B. taurus x B. indicus) Vechur cattle response bacterial endotoxin-lipopolysaccharide (LPS). The PBMCs from adult apparently healthy female cows cattle, a native breed Kerala, India were stimulated with 10 μg/mL LPS for 6 h. Among differentially expressed miRNAs, 13 showed statistically significant up...
An insertion/deletion (InDel) polymorphism study of PR/SET domain family 6 (PRDM6), myostatin (MSTN) and insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) genes was conducted in Malabari Attappady black goats. association identified InDels body measurement traits also performed. Body measurements included length, chest diameter, depth, canon circumference, hip width, height at the cross. The trunk index, length circumference width index were calculated. Hardy-Weinberg equilibrium...
Tinospora cordifolia (TC) is one of the most versatile medicinal plants in Ayurvedic medicine used for treatment various ailments. The present study was carried out to investigate vitro cytotoxicity aqueous extract TC stems on Dalton’s lymphoma ascites (DLA) cell lines comparison with a reference drug, cisplatin through 3-(4, 5-dimethylthiazol-2-yl)-2, 5-phenyl tetrazolium bromide assay (MTT) and Trypan blue dye exclusion methods. Phytochemical analysis revealed presence alkaloids,...