A5005309170- Renal cell carcinoma treatment
- Epigenetics and DNA Methylation
- Renal and related cancers
- Orthodontics and Dentofacial Orthopedics
- Genetic and Kidney Cyst Diseases
- Mechanisms of cancer metastasis
- Dental Radiography and Imaging
- Temporomandibular Joint Disorders
- Dental Implant Techniques and Outcomes
- Cancer-related gene regulation
- RNA Interference and Gene Delivery
- Nitrogen and Sulfur Effects on Brassica
- Microtubule and mitosis dynamics
- Advanced biosensing and bioanalysis techniques
- Ubiquitin and proteasome pathways
- Genomics and Chromatin Dynamics
- Facial Trauma and Fracture Management
- Dental materials and restorations
- Virus-based gene therapy research
- dental development and anomalies
- Biopolymer Synthesis and Applications
- Orthopaedic implants and arthroplasty
- Glutathione Transferases and Polymorphisms
- Histone Deacetylase Inhibitors Research
- biodegradable polymer synthesis and properties
Hallym University
2014-2025
Hallym University Sacred Heart Hospital
2015-2025
Hallym University Medical Center
2024-2025
Tongmyong University
2024
Korea Research Institute of Bioscience and Biotechnology
2000-2023
Baylor College of Medicine
2016-2021
Inha University
2021
Weatherford College
2020
Chuncheon Sacred Heart Hospital
2015-2020
Texas A&M Health Science Center
2015-2017
Abstract We searched for potential suppressors of tumor metastasis by identifying the genes that are frequently down-regulated in hepatocellular carcinomas (HCC) while being negatively correlated with clinical parameters relevant to metastasis, and we report here on identification N-myc downstream regulated gene 2 (NDRG2) as a promising candidate. NDRG2 expression was significantly reduced HCC compared nontumor or normal liver tissues [87.5% (35 40) 62% (62 100) at RNA protein levels,...
Many reports have been published on orthognathic surgery (OGS) using computer-aided surgical simulation (CASS). The purpose of this study was to evaluate the accuracy maxillary repositioning and stability maxilla in patients who underwent OGS a newly developed CASS program, customized osteotomy guide, miniplate. Thirteen from 2015 2017 were included. All bimaxillary operation. First, skull-dentition hybrid 3D image rendered by merging cone beam computed tomography (CBCT) images with...
Abstract Lateral cephalograms and related analysis constitute representative methods for orthodontic treatment. However, since conventional cephalometric radiographs display a three-dimensional structure on two-dimensional plane, inaccuracies may be produced when quantitative evaluation is required. Cone-beam computed tomography (CBCT) has minimal image distortion, important parts can observed without overlapping. It provides high-resolution at relatively low dose cost, but still shows...
SETD2 regulates actin dynamics and cell migration via methylation of at Lys 68 in a cellular complex containing Huntingtin.
Objective: Digital twins of adult Korean females were created as a tool to evaluate and compare the sagittal relationship between maxillary central incisors forehead before after orthodontic treatment. Methods: reconstructed for total 50 female patients using facial scans cone-beam computed tomography (CBCT) images. The anteroposterior position incisor inclination measured. Results: control group presented mean 6.7 mm 17.5° inclination. study showed 9.3 13.6° Most seeking treatment had their...
Abstract Distortion of dentition may occur in cone-beam computed tomography (CBCT) scans due to artifacts, and further imaging is frequently required produce digital twins. The use a plaster model common; however, it has certain drawbacks. This study aimed assess the feasibility different models over that casts. Plaster models, alginate impressions, intraoral scan (IOS) images, CBCT images 20 patients were obtained. desktop scanner was used impression twice, five minutes two hours after...
Multi-dimensional facial imaging is increasingly used in hospital clinics. A digital twin of the face can be created by reconstructing three-dimensional (3D) images using scanners. Therefore, reliability, strengths, and weaknesses scanners should investigated approved; Methods: Images obtained from three (RayFace, MegaGen, Artec Eva) were compared with cone-beam computed tomography as standard. Surface discrepancies measured analyzed at 14 specific reference points; Results: All this study...
With the growing demand for orthognathic surgery and other facial treatments, accurate identification of anatomical landmarks has become crucial. Recent advancements have shifted towards using three-dimensional radiologic analysis instead traditional two-dimensional methods, as it allows more precise treatment planning, primarily relying on direct by clinicians. However, manual tracing can be time-consuming, mainly when dealing with a large number patients. This study compared accuracy...
<title>Abstract</title> <bold>Objectives</bold>: Orthognathic surgery aims to correct dentofacial deformities by repositioning the maxillomandibular complex. The advent of digital technology, particularly Virtual Surgical Planning (VSP), has enhanced precision and efficiency these procedures. Despite this, comparative analyses VSP software accuracy remain limited. This study evaluates across multiple platforms examines time-saving potential Artificial Intelligence (AI)-assisted cephalometry....
Dental implants rely on precise prosthetic design and biomechanical stability to ensure long-term success. This study evaluates the mechanical performance of non-engaging abutments in multi-unit combined screw- cement-retained prostheses (CSCRP) using two internal implant systems: BlueDiamond (BD) AnyOne (AO) systems. Unlike conventional systems that utilize same type screw for both engaging abutments, BD system employs a distinct abutments. A total 80 were tested, with 40 each group....
Methyl marks made by the epigenetic writer SETD2 recruit reader PBRM1 to spindle microtubules during mitosis.
Abstract To ascertain whether p53 deficiency in vivo leads to the deregulation of DNA methylation machinery prior tumor development, we investigated expression profile methyltransferases thymus and liver +/+ , +/− −/− mice at 7 weeks age before development. The was examined age, since malignant T‐cell lymphoma develops most frequently around 20 age. Both mRNA protein levels Dnmt1 Dnmt3b were increased ‐deficient mice. Dnmt3a also but not Dnmt3L reduced total 5‐methylcytosine (5‐MeC) genomic...
To develop the functionalized superparamagnetic iron oxide nanoparticles (SPIONs) demonstrating capacities to be delivered in antigen presenting cells specifically and dispersed physiological environment stably, nanoparticle surface was coated with mannan that induces receptor-mediated endocytosis. Mannan is a water-soluble polysaccharide having high content of D-mannose residues recognized by mannose receptors on immunate macrophages. Mannan-coated SPIONs (mannan-SPIONs) were prepared...
Accumulating evidence has shown a close connection between hematopoiesis and bone formation. Our aim was to evaluate the association peripheral blood cell counts mineral density (BMD) in sample of postmenopausal women.