A5080297652- Mycotoxins in Agriculture and Food
- Rabbits: Nutrition, Reproduction, Health
- Plant Toxicity and Pharmacological Properties
- Plant Disease Resistance and Genetics
- Ruminant Nutrition and Digestive Physiology
- Plant and fungal interactions
- Plant Pathogens and Fungal Diseases
- Carcinogens and Genotoxicity Assessment
- Animal Nutrition and Physiology
- Indoor Air Quality and Microbial Exposure
- Sperm and Testicular Function
- Agricultural safety and regulations
- Wheat and Barley Genetics and Pathology
- Heat shock proteins research
- Probiotics and Fermented Foods
- Immunotoxicology and immune responses
- Bee Products Chemical Analysis
- Meat and Animal Product Quality
Magyar Agrár- és Élettudományi Egyetem
2021
University of Kapsovar
2014-2019
Male Wistar rats were treated intraperitoneally (i.p.) with fumonisin B1 (FB1; 0, 20, 50 and 100 mg/kg dietary dose equivalent) for 5 10 days (n = 24–24 in each setting) to gain dose- time-dependent effects on antioxidant status oxidative stress response, clinical chemical endpoints liver, kidney lung histopathology lymphocyte damage (genotoxicity). FB1 decreased feed intake, body weight absolute liver weight, irrespective of the toxin dose. Relative increased 10-day setting. Linear response...
Abstract To test the complex, acute biochemical effects of combined, naturally co‐occurring fusariotoxins, a 5‐day rat study was performed. Mycotoxin treatment invented by intraperitoneal injection: FB 1 (F): 9 µg/animal/day (approx. 30 µg/kg bw/day), DON (D): 16.5 55 bw/day) and ZEN (Z): 12.75 42.5 bw/day). The binary groups (FB [FD], [FZ] [DZ]) as well ternary , [FDZ]) group were dosed at same combined level individual mycotoxins. Body weight, feed intake mortality not affected any...
Fusarium mycotoxins, such as fumonisin B1 (FB1), deoxynivalenol (DON) and zearalenone (ZEN), frequently co-occur in feed raw materials their presence is ubiquitous. The aims of this study were to determine the concentration that inhibits cell viability by 50% (IC50 values) for each mycotoxin (after 24, 48 72 h) investigate combined effects binary (DON + ZEN: DZ, DON FB1: DF, FB1 FZ) ternary (DFZ) mixtures using cyto- genotoxicity on porcine lymphocytes endpoints. potency cytotoxicity three...
As the most common grain contaminant worldwide, deoxynivalenol is of high importance despite its low toxicity compared to other trichothecene mycotoxins. Data on effects in rabbits are scarce. Thus, aim this study was investigate dietary fed at a level (10 mg/kg feed) productive performance, blood indices, immunological variables, histopathological changes, and genotoxicity rabbits. Forty-eight Pannon White were exposed contaminated diets for three weeks. Despite concentration, did not...
Abstract The heat shock protein (Hsp70) level was assessed after 14 days of oral gavage-exposure to fumonisin B 1 (FB : 150 µg/animal/day), deoxynivalenol (DON: 30 µg/animal/day) and zearalenone (ZEN: alone or in combinations (in additive manner: FD = FB + DON, FZ ZEN, DZ DON ZEN FDZ ZEN) the liver, kidneys lung 24 adult male Wistar rats ( n 3/group). liver most responsive tissue, as compared with kidney lung. Except DZ-treatment, mycotoxins elevated Hsp70 levels livers. highest Hsp70-levels...
Conventional analytical methods used for the analysis of fumonisin content in animal feeds fail to take into account bound matrix, which is otherwise bioaccessible and can be absorbed from gastrointestinal tract. Moreover, underestimation using routine affect experiments cereals contaminated by fungi. In present study, hidden B 1 was analysed two cereal substrates (maize wheat) were inoculated with Fusarium verticillioides (MRC 826). The study compared a extraction procedure an vitro...
Fumonisin-producing fungal species, Fusarium verticillioides , culture was mixed in the diets of 6 piglets for 9 days (Fumonisin B 1 [FB ] intake 17 mg/kg) to investigate whether there is any potential alteration caecal bacterial communities between experimental (with F. ) and control groups (without ). Plate count agar culturing technique applied measure amount aerobic anaerobic bacteria, Escherichia coli coliforms, Lactobacillus spp. Clostridium perfringens . A significant difference...
Contamination of feed with mycotoxins is a common problem encountered in animal farming. Mycotoxin exposure can affect adversely the health animals. In rabbits caecal fermentation an essential digestive process being indication physiological alterations. Deoxynivalenol (DON) one most frequent contaminants grains which growth monogastric Data about dietary DON and its effect are scarce. Medicinal plants often used as additives to enhance performance Carduus marianus (milk thistle) known for...