A5059857211- Mycotoxins in Agriculture and Food
- Plant Pathogens and Fungal Diseases
- Wheat and Barley Genetics and Pathology
- Pesticide Residue Analysis and Safety
- Phytochemicals and Antioxidant Activities
- Plant and fungal interactions
- Pituitary Gland Disorders and Treatments
- Plant Disease Resistance and Genetics
- Advanced Chemical Sensor Technologies
- Meat and Animal Product Quality
- Potato Plant Research
- Insect and Pesticide Research
- Carcinogens and Genotoxicity Assessment
- Food composition and properties
- Fermentation and Sensory Analysis
- Agricultural safety and regulations
- Light effects on plants
- Analytical Chemistry and Chromatography
- Adrenal Hormones and Disorders
- Identification and Quantification in Food
- Plant Pathogens and Resistance
- Spectroscopy and Chemometric Analyses
- Nuts composition and effects
- Adrenal and Paraganglionic Tumors
- Metabolomics and Mass Spectrometry Studies
University of Parma
2016-2025
Waters (United States)
2024
Istituto Superiore di Sanità
2020
Institute of Food Science
2012
University of Milan
1999-2009
Ospedale San Paolo
2009
Ospedale San Paolo
2007-2009
Ospedale Maggiore
2000-2009
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2000-2009
Ospedale Bellaria
2009
We investigated the hypothesis that resistance to deoxynivalenol (DON) is a major factor in Fusarium head blight (FHB) complex of wheat. Ninety-six double haploid lines from cross between ‘CM-82036’ and ‘Remus’ were examined. The tested for DON after application toxin ear, resistances initial infection spread FHB artificial inoculation with spp. Toxin flowering ears induced typical symptoms. Quantitative trait locus (QTL) analyses detected one effect on (logarithm odds = 53.1, R 2 92.6)....
Conjugated mycotoxins, in which the toxin is usually bound to a more polar substance like glucose, are referred as masked these substances escape routine detection methods but can release their toxic precursors after hydrolysis. This first report on natural occurrence of glucoside deoxynivalenol (DON) Fusarium-infected wheat and maize. To obtain appropriate standards, we chemically synthesized deoxynivalenol-3-beta-D-glucopyranoside (DON-3-glucoside) deoxynivalenol-15-beta-D-glucopyranoside...
The comprehensive identification of phenolic compounds in food and beverages is a crucial starting point for assessing their biological, nutritional, technological properties. Pomegranate (Punica granatum L.) has been described as rich source (poly)phenolic components, with broad array different structures (phenolic acids, flavonoids, hydrolyzable tannins) quick, high throughput, accurate screening its complete profile still lacking. In the present work, method UHPLC separation linear ion...
The European Commission asked EFSA to update their 2006 opinion on ochratoxin A (OTA) in food. OTA is produced by fungi of the genus
Zearalenone (ZEN), a mycotoxin primarily produced by Fusarium fungi, occurs predominantly in cereal grains.The European Commission asked EFSA for scientific opinion on the risk to animal health related ZEN and its modified forms feed.Modified of occurring feed include phase I metabolites a-zearalenol (a-ZEL), b-zearalenol (b-ZEL), a-zearalanol (a-ZAL), b-zearalanol (b-ZAL), zearalanone (ZAN) II conjugates.ZEN has oestrogenic activity differs considerably.For ZEN, Panel Contaminants Food...
This paper presents a comprehensive analysis of the phytochemical profile proprietary rosemary (Rosmarinus officinalis L.) extract rich in carnosic acid. A characterization (poly)phenolic and volatile fractions was carried out using mass spectrometric techniques. The composition assessed by ultra-high performance liquid chromatography-electrospray ionization-mass spectrometry (UHPLC-ESI-MSn) total 57 compounds were tentatively identified quantified, 14 these being detected for first time....
The incidence of adrenal incidentalomas has sharply increased in recent decades and concurrent subtle endocrine abnormalities, or even subclinical conditions, have been identified. Nonetheless, data concerning possible changes size and/or hormonal pattern during follow-up are still inadequate.To evaluate long-term morphological functional evolution after initial diagnosis to identify risk factors for hyperactivity mass enlargement.Sixty-four patients (34-79 years) were followed-up 12-120...
Although most rice cultivars have whitish kernel, some varieties a red testa. Aim of this work was to compare the total antioxidant capacity (TAC) and chemical composition (namely tocols, gamma-oryzanols, polyphenols) white rices. In addition, effect milling cooking on antioxidants investigated in both Dehulled showed TAC more than three times greater dehulled its high essentially characterized by presence proanthocyanidins (PA) associated phenolics. Milling caused significant loss TAC, even...
Fusarium mycotoxins are secondary metabolites produced by spp. in cereals. Among them, deoxynivalenol (DON) and zearalenone (ZEN) widespread worldwide contaminants of cereal commodities ranked as the most important chronic dietary risk factors. Their conjugates, known masked mycotoxins, have been described but still not accounted for assessment studies. This study demonstrates first time that DON ZEN effectively deconjugated human colonic microbiota, releasing their toxic aglycones...
Deoxynivalenol-3-β-D-glucoside (D3G), a phase II plant metabolite of the mycotoxin deoxynivalenol (DON), occurs in naturally Fusarium-contaminated cereals. In order to investigate frequency occurrence as well relative and absolute concentrations D3G infected cereals, 23 wheat samples originating from fields Austria, Germany Slovakia 54 maize Austrian were analysed for DON by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Both analytes detected all 77 field samples. was found at...
The present paper reports a complete mass spectrometric characterization of both the phenolic and volatile fractions dried spearmint extract. Phenolic compounds were analysed by ultra-high performance liquid chromatography-electrospray ionization-mass spectrometry (UHPLC-ESI-MSn) total 66 tentatively identified, being widest characterisation to date. analysis suggests that extract is composed rosmarinic acid its derivatives (230.5 ± 13.5 mg/g) with smaller amounts salvianolic acids,...
The EFSA Panel on Contaminants in the Food Chain (CONTAM) established a tolerable daily intake (TDI) for fumonisin B
Fumonisins, mycotoxins primarily produced by Fusarium verticillioides and proliferatum, occur predominantly in cereal grains, especially maize. The European Commission asked EFSA for a scientific opinion on the risk to animal health related fumonisins their modified hidden forms feed. Fumonisin B1 (FB 1), FB 2 3 are most common of feedstuffs thus were included assessment. 1, have same mode action considered as having similar toxicological profile potencies. For fumonisins, Panel Contaminants...
Abstract Rice is part of many people's diet around the world, being main energy source in some regions. Although fewer reports exist on occurrence mycotoxins rice compared to other cereals, fungal contamination and associated production toxic metabolites, even at lower levels crops, are concern because high consumption countries. Due diversity fungi that may contaminate food chain, co‐occurrence frequent. Specific strategies overcome these problems be applied preharvest crop while assuring...
This study aimed to present the occurrence of sixteen mycotoxins in 105 meat alternatives based on wheat, legumes, and vegetables from Italy. The targeted were aflatoxins (AFB1, AFB2, AFG1, AFG2), fumonisins B1 B2 (FB1, FB2), alternariol (AOH), monomethyl ether (AME), tentoxin (TEN), ochratoxin A (OTA), zearalenone (ZEN), T-2/HT-2 toxin, deoxynivalenol (DON), enniatin B (ENNB), beauvericin (BEA). was between 0% (AFB2) – 97.4% (ENNB). Mycotoxin co-occurrence varied binary combinations up...
OBJECTIVE: Rosiglitazone, a thiazolidinedione compound with peroxisome proliferator-activated receptor-gamma (PPAR-gamma)-binding affinity, is able to suppress adrenocorticotropic hormone (ACTH) secretion in treated mice and AtT20 pituitary tumor cells. These observations suggested that thiazolidinediones may be effective as therapy for Cushing's disease (CD). PATIENTS AND METHODS: Rosiglitazone (8 mg/day) was administered 14 patients active CD (13 women, one man, 18-68 years). Plasma ACTH,...