A5039951700- Obsessive-Compulsive Spectrum Disorders
- Dementia and Cognitive Impairment Research
- Neurobiology of Language and Bilingualism
- Face and Expression Recognition
- Neural Networks and Applications
- Mental Health Treatment and Access
- Face Recognition and Perception
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Treatment of Major Depression
- Schizophrenia research and treatment
- Autism Spectrum Disorder Research
- Psychiatric care and mental health services
- Child and Adolescent Psychosocial and Emotional Development
- Categorization, perception, and language
- Face recognition and analysis
- Mental Health and Patient Involvement
- Mental Health Research Topics
- Child and Animal Learning Development
- Biomedical Text Mining and Ontologies
- Eating Disorders and Behaviors
- Health Systems, Economic Evaluations, Quality of Life
- Functional Brain Connectivity Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Visual perception and processing mechanisms
- Alzheimer's disease research and treatments
Hertfordshire Partnership University NHS Foundation Trust
2012-2024
University of Hertfordshire
2012-2022
Creative Research Enterprises (United States)
2016
University of Bedfordshire
2014
University Foundation
2013-2014
Queen Elizabeth II Hospital
2003-2013
Queen Elizabeth Hospital
2002-2005
Hertfordshire Community NHS Trust
1998-2004
In-Q-Tel
2001
Obsessive–compulsive disorder is a prevalent and disabling lifespan disorder. Clomipramine the SSRIs have been found to be effective across range of symptoms, both in acute longer-term studies. Meta-analyses reported larger treatment effect for clomipramine relative SSRIs, but this not supported by evidence from head-to-head comparator studies and, based on their superior safety tolerability, are preferred option long-term most cases. The treatment-effect usually gradual partial, many...
Objective. Prospective longitudinal studies of obsessive-compulsive disorder (OCD) and sub-diagnostic symptomatology in the non-clinical population, using age-defined cohorts, are rare. This study aimed to investigate effect OC symptoms on distress psychosocial function early-onset symptoms. Methods. 591 subjects drawn from general population Zurich, Switzerland were interviewed seven times between 1979 (at age 20/21) 2008 (age 49/50). Data for socio-demographic variables impairment was also...
This study aims to expand the available knowledge on Obsessive Compulsive Disorder (OCD)-comorbidity by investigating prevalence and clinical impact a group of individuals with OCD or subthreshold OC syndrome (OCS), prospectively followed-up over an extended period.A stratified sample general population canton Zurich, Switzerland (n = 591), participated in series seven interviews 30-year period. Clinically significant comorbid subgroups OCD/OCS were compared cases without respective...
This study aimed to determine the efficacy and tolerability of adding quetiapine a serotonin reuptake inhibitor in treatment-resistant obsessive-compulsive disorder (OCD). Twenty-one adult OCD patients were randomized 16 weeks augmentation with either (n = 11) or placebo 10). Patients significant comorbidities, including tic-spectrum disorders, not included. The treatment was well tolerated, only one premature dropout each treatment-group. primary analysis showed that individuals...
Abstract We present a new corpus of 147 high-quality photographic colour images (the Hatfield Image Test: HIT). Existing sets pictorial stimuli tend to be line drawn, contain many items that are readily identifiable by healthy participants, and, therefore, have an inherent tendency towards ceiling effects in the normal population. The broad range item difficulty and semantic subcategories HIT permits researchers select appropriate as required. naming data from 152 participants. Additionally,...
Studies suggest that obsessive-compulsive disorder (OCD) is an unremitting disorder. We report a prospective, longitudinal investigation into OCD and sub-diagnostic OC syndrome (OCS) over 30-year period to determine the extent which individuals with clinically relevant symptomatology cumulatively remit, as well remission latency.Five hundred ninety-one participants drawn from general population of Zurich, Switzerland, participated in series seven interviews 30 years.Median duration for OCD,...
Aims and method To determine which terms receivers of mental health services wish to be known by (service user, patient, client, survivor) according the professional consulted (psychiatrist, nurse, psychologist, social worker, occupational therapist). We conducted a questionnaire study assess like or dislike rank order. There were 336 participants from local catchment area secondary care community in-patient settings in east Hertfordshire. Results Patient is preferred term when psychiatrists...
Article Abstract Background: This study was prompted by reports suggesting a high prevalence of unrecognized obsessive-compulsive disorder (OCD) in the dermatology clinic. Method: 92 consecutive referrals were screened for DSM-IV OCD using Mini-International Neuropsychiatric Inverview (MINI), Yale-Brown Obsessive Compulsive Scale (YBOCS), and 5-item screening questionnaire from International Council on OCD. Illness severity rated YBOCS, symptom profiles dermatologic diagnoses established...
Background: The NSF specifies that mental health service providers should have a locally agreed proforma for assessing risk. Risk assessment proformas (RAPs) currently in use vary considerably both structure and content. This study describes some similarities differences.Method: We requested copy of each provider trust's RAP. These were assessed across range structural characteristics, including layout, design, data coding, also studied their content.Results: Some consistency was seen the...
Background A variety of depression rating scales are currently used in clinical and research practice. As these generally thought to correlate well, there may be some benefit deriving equations translate the score on one scale that another. Method Using pairwise ratings, we compared Montgomery‐Åsberg Depression Rating Scale (MÅDRS), Beck Inventory II (BDI‐II), Patient Health Questionnaire (PHQ‐9) Zung Self Rated (SRS). The primary comparisons interest were as follows: PHQ‐9 MÅDRS, BDI‐II,...