A5086630622- Nanoparticles: synthesis and applications
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Laser-Ablation Synthesis of Nanoparticles
- Nanotechnology research and applications
- Advanced Nanomaterials in Catalysis
- MicroRNA in disease regulation
- Pharmacological Effects of Natural Compounds
- Computational Drug Discovery Methods
- Ginger and Zingiberaceae research
- Biocrusts and Microbial Ecology
- Drug-Induced Hepatotoxicity and Protection
- Pharmacology and Obesity Treatment
- Ginseng Biological Effects and Applications
- Cancer, Hypoxia, and Metabolism
- Algal biology and biofuel production
- SARS-CoV-2 and COVID-19 Research
- Moringa oleifera research and applications
- Signaling Pathways in Disease
- Tea Polyphenols and Effects
- PI3K/AKT/mTOR signaling in cancer
- Sirtuins and Resveratrol in Medicine
- Diverse Scientific Research Studies
- Nanoparticle-Based Drug Delivery
- Synthesis and biological activity
Princess Nourah bint Abdulrahman University
2015-2024
King Khalid University
2017
Universidade Federal do ABC
2013
Synthesis of Silver Nanoparticles Using a Novel Cyanobacteria Desertifilum sp. extract: Their Antibacterial and Cytotoxicity Effects Reham Samir Hamida,1 Nabila Elsayed Abdelmeguid,1 Mohamed Abdelaal Ali,2 Mashael Mohammed Bin-Meferij,3 Mahmoud Ibrahim Khalil4 1Molecular Biology Unit, Department Zoology, Faculty Science, Alexandria University, Alexandria, Egypt; 2Biotechnology Plant Production, College Food Agriculture King Saud Riyadh, Saudi Arabia; 3Department Biology, Science Princess...
Microalgae-mediated synthesis of nanoparticles (NPs) is an emerging nanobiotechnology that utilizes the biomolecular corona microalgae as reducing and capping agents for NP fabrication. This study screened a novel microalgal strain its potential to synthesize silver (Ag)-NPs then assayed biological activities NPs. Coelastrella aeroterrestrica BA_Chlo4 was isolated, purified, morphologically molecularly identified. Chemical composition algal extract determined by GC-MS analysis. Ag-NPs were...
Green nanoparticles represent a revolution in bionanotechnology, providing opportunities to fight life-threatening diseases, such as cancer, with less risk the environment and human health. Here, for first time, we systematically investigated anticancer activity possible mechanism of novel silver (N-SNPs) synthesized by Nostoc Bahar M against MCF-7 breast cancer cells, HCT-116 colorectal adenocarcinoma HepG2 liver using cell viability assays, morphological characterization inverted light...
Over recent years, green chemistry procedures have been developed to synthesize nanoparticles in eco-friendlier and less expensive ways. These use natural sources such as bacteria, fungi, yeast, plants, actinomycetes, algae, or cyanobacteria, biomolecules proteins, vitamins, pigments instead of chemical materials fabricate salt precursors into nanoparticles.In the current investigation, we an effective, inexpensive, nontoxic method silver (SNPs) using cellular extract a novel strain...
Among various routes of metallic nanoparticle (NPs) fabrication, phytosynthesis has significant advantages over other conventional approaches. Plant-mediated synthesis NPs is a fast, one-step, ecobenign, and inexpensive method with high scalability. Herein, silver (Ag) gold (Au)-NPs were extracellularly synthesized using aqueous Haloxylon salicornicum (H@Ag-, H@Au-NPs) leaf extracts. GC-MS was performed to analyze the chemical compositions H. extract. H@Ag- H@Au-NPs characterized via UV-Vis...
Severe destructive hepatic injuries can be induced by acetaminophen overdose and may lead to acute failure.To investigate the ameliorative effects of Arctium lappa root extract on acetaminophen-induced hepatotoxicity.Rats were divided into 4 groups: normal control group, acetaminophen-injected treated with group.The treatment reduced serum alanine transaminase, aspartate aminotransferase, alkaline phosphatase in group when compared group. DNA fragments also significantly increased (P <...
Algal-mediated synthesis of nanoparticles (NPs) opens the horizon for green and sustainable NPs that can be used in many fields, such as medicine industry. We extracellularly synthesized silver (Ag-NPs) using novel microalgae Planophila laetevirens under optimized conditions. The isolate was collected from freshwater/soil, purified, morphologically identified, genetically identified light, inverted scanning electron microscopy, 18S rRNA sequencing. phytochemicals algal extract were detected...
Algal-mediated synthesis of nanoparticles (NPs) is an eco-friendly alternative for producing NPs with potent physicochemical and biological properties. Microalgae represent ideal bio-nanofactory because they contain several biomolecules acting as passivation stabilising agents during the biogenesis NPs. Herein, a novel microalgae sp. was isolated, purified, identified using light electron microscopy 18s rRNA sequencing. The chemical components their watery extract were assessed GC-MS. Their...
Phormidesmis communis strain AB_11_10 was isolated and identified using microscopy 16s rRNA sequencing, its phytochemical constituents were determined liquid chromatography-quadrupole time-of-flight mass spectrometry. The isolate had a segmented filamentous shape with blue-green color. Many biomolecules, including organic compounds, amino acids, fatty detected. P. used to synthesize gold nanoparticles (Ph-AuNPs) by adjusting the optimum reaction conditions. concentration, algal/precursor...
Microalgae-mediated nanoparticle (NP) biosynthesis is a promising green synthesis method that overcomes the challenges of conventional methods. The novel Desmochloris edaphica strain CCAP 6006/5 was isolated, purified, and characterized morphologically genetically. GC-MS analysis algal biomass (DBio) phytochemicals showed abundance for elaidic acid (18.36%) monoolein (17.37%). UV-VIS spectroscopy helped analyze effects AgNO3 concentration, algal/silver nitrate ratio, temperature, reaction...
This study investigated whether the mechanism underlying neurotoxic effects of cadmium chloride (CdCl 2 ) in rats involves p 66 Shc. comprised an initial vivo experiment followed by vitro experiment. For experiment, male were orally administered saline (vehicle) or CdCl (0.05 mg/kg) for 30 days. Thereafter, spatial and retention memory tested their hippocampi used biochemical molecular analyses. control Shc-deficient hippocampal cells treated with (25 µM) presence absence SP600125, a c-Jun...
The deadliest recent pandemic outbreak of COVID-19 disease has severely damaged the socio-economic health people globally. Due to unavailability any effective vaccine or treatment human beings are still struggling overcome condition. In an attempt discover anti-COVID molecule, we used in-silico approach and reported 160 natural polyphenols identify most promising druggable HITs that can further for drug discovery process. co-crystallized structure COVID protease enzyme (PDB id 6LU7) was...
Abstract This study aimed to investigate the major salivary glands in southern white‐breasted hedgehog ( Erinaceus concolor ) histologically and histochemically. Five adult males were included this study. The results showed that anatomically shape of parotid, submandibular sublingual was respectively almost pear, elliptical pyramidal oval. Histologically, parotid gland had serous acini secretory cells negative reaction alcian blue (AB) (pH = 2.5) response aldehyde fuchsin (AF), methylene...
Purpose: The biological synthesis of nanoparticles (NPs) has become a new methodology for the eco-friendly production NPs with high scalability and biocompatibility. Cyanobacteria are one most widespread microorganisms on Earth have been proven to be successful biofactories synthesizing NPs. It is challenging discover microalgae potential synthesize small size stability. Methods: Nostoc muscorum Lukesova 2/91 was isolated, purified, identified morphologically genetically using microscopy DNA...
Background and Objective: Obesity is a chronic, multifactorial disease that develops from the interaction of behavioral, physiological, metabolic, cellular molecular factors.High fat diet produces consistent significant increase (p<0.05) in body content which dependent on both amount duration feeding.So, this study was aimed to investigate effects ginger extract obesity hepatosteatosis obese rats-induced by high its capability antioxidants-rich protecting rats against complications.Materials...
The study examined the protective effect of exogenous administration dehydroepiandrosterone (DHEA) against acetaminophen (APAP) -induced liver damage in rats and tested underlying mechanism(s). Male were divided into 5 groups as control, control + DHEA, APAP, APAP DHEA EX-527 (SIRT1 inhibitor). Treatments conducted for 10 days then followed by intragastric a single dose APAP. not only reduced serum alanine transaminase (ALT) aspartate aminotransferase (AST) but also preserved structures....