A5038360479- Adipose Tissue and Metabolism
- Muscle metabolism and nutrition
- Diet and metabolism studies
- Metabolism, Diabetes, and Cancer
- Nutrition and Health in Aging
- Cardiovascular and exercise physiology
- Diabetes Treatment and Management
- Body Composition Measurement Techniques
- Pancreatic function and diabetes
- Diet, Metabolism, and Disease
- Diabetes Management and Research
- Physical Activity and Health
- Biochemical Acid Research Studies
- Natural Antidiabetic Agents Studies
- Exercise and Physiological Responses
- Metabolism and Genetic Disorders
- Diabetes Management and Education
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Disease and Adiposity
- Pharmacology and Obesity Treatment
- Health and Wellbeing Research
- Sports Performance and Training
- Mitochondrial Function and Pathology
- Thermoregulation and physiological responses
- Adipokines, Inflammation, and Metabolic Diseases
Nagoya University
2013-2022
National Sanyo Hospital
2020-2022
Aichi Gakuin University
2007
Nagoya Institute of Technology
1996-2000
National Defense Medical College Hospital
1999
University of Tsukuba
1999
Dongguk University
1999
Aichi Medical University
1990-1995
To construct an East Asia mitochondrial DNA (mtDNA) phylogeny, we sequenced the complete genomes of 672 Japanese individuals ( http://www.giib.or.jp/mtsnp/index_e.html ). This allowed us to perform a phylogenetic analysis with pool 942 Asiatic sequences. New clades and subclades emerged from data. On basis this unequivocal classified 4713 Asian partial sequences, <10% ambiguity. Applying population phylogeographic methods, used these sequences shed light on controversial issue peopling...
OBJECTIVE To evaluate the effects of walking combined with diet therapy (1,000–1,600 kcal/day) on insulin sensitivity in obese non-insulin-dependent diabetes mellitus (NIDDM) patients. RESEARCH DESIGN AND METHODS Subjects were divided into two groups: 10 patients managed by alone (group D), and 14 placed exercise group DE). Group DE was instructed to walk at least 10,000 steps/day a flat field as monitored pedometer (19,200 ± 2,100 steps/day), D told maintain normal daily routine (4,500 290...
Physical training has been shown to improve glucose tolerance and insulin sensitivity. In the present study, action was determined using euglycemic clamp technique in six untrained nonobese subjects before, during, after long-term mild regular jogging. After 1 yr of jogging, steady-state plasma levels (I) decreased significantly, metabolic clearance rate increased by 87%, although infusion during constant for each individual. The amount infused (glucose metabolism, M) tended increase from...
Fat infiltration within skeletal muscle is known as intramuscular fat (IMF), which increases with aging. Studies have assessed IMF content, using the mid-thigh a representative location. However, three-dimensional distribution not well understood. The aim of this study was to compare content in young and old adults by assessing its along length thigh. Consecutive transaxial images right thighs 15 (age, 21.0 ± 0.4) 70.7 3.8) were obtained magnetic resonance imaging. We measured...
Glucagon, a counterregulatory hormone to insulin, serves as regulator of glucose homeostasis and acts in response hypoglycemia. Earlier studies have shown that glucagon administration induces thermogenesis experimental animal models. However, it is not known whether endogenous involved the regulation brown adipose tissue (BAT) function. Here we investigated role cold-induced male mice deficient proglucagon-derived peptides (GCGKO mice). Upon exposure cold, GCGKO exhibited greater decrease...
Older individuals have been shown to present muscle atrophy in conjunction with increased fat fraction some muscles. The proportion of and connective tissue within the skeletal can be estimated from axial B-mode ultrasound images using echo intensity (EI). EI was used calculate index quality. Walking, home-based weight-bearing resistance training, its combinations are considered simple, easy, practical exercise interventions for older adults. purpose this study quantify effects walking...
To clarify the difference in immunity between untrained subjects and well-trained athletes, number of total leukocytes (WBC), lymphocytes, neutrophils, percentages various lymphocyte subpopulations (OKT3, OKT4, OKT8, Leu7, OKIa1), levels transformation response to phytohemagglutinin (PHA) were determined five male six athletes before, immediately after, 24 72 h after acute physical exercise at 60% VO2max for 2 h.
To elucidate the possible role of hyperinsulinism in etiology diabetic macroangiopathy, we studied long-term effects insulin injection on arterial wall rat both biochemically and histologically. Fifty male Wistar rats were divided into two groups. One group was subjected to daily insulin-zinc suspension (20 U/kg), other treated with saline. After 1 yr, all animals killed, lipid contents intimal media their aortas determined. Parts ascending aortic tissues further examined by use either light...
Physical training has been shown to improve glucose tolerance and insulin action. In the present study, action was determined using euglycemic clamp technique in six trained male athletes compared with untrained controls matched by age, sex, weight at 14, 38, 86 hours 6 days after cessation of exercise. The rate insulin-mediated uptake (glucose disposal) 9.40 ± 0.46 mg · kg-1 min-1 (mean SEM) for 14 h last exercise bout, 6.80 0.86 obtained (p < 0.01). Glucose disposal gradually decreased...
To clarify the associations of periodontal damage and tooth loss with atherogenic factors among diabetic patients.We examined correlations age, sex, smoking, oral hygiene score, blood pressure, body mass index, chemical data mean depth pockets or number remaining teeth.One hundred outpatients type 2 diabetes aged 29 to 77 years.The was significantly associated HbA1c; Spearman correlation coefficients (r) were 0.220, 0.417, 0.260, respectively. Age, HbA1c inversely correlated teeth (r=-0.306,...
Black soybeans (Glycine max (L.) Merr.) are known to be rich in polyphenols, including anthocyanins, and they have been consumed since ancient times for their beneficial effects on health. In addition, it has reported that black soybean (BS) seed coat may ameliorate obesity insulin resistance. the present study, we administered BS extract type 2 diabetics months investigate of glycemic control lipid metabolism parameters. antihyperlipidemic agent, fenofibrate, patients with diabetes...
Dipeptidyl peptidase-4 (DPP-4) inhibitors have been reported to improve the glycemic control and blood hemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>) concentrations. However, there are few reports as yet suggesting that DPP-4 may also insulin resistance serum lipid profile in clinical setting. This study was aimed at investigating effect of 14-week treatment with teneligliptin (20 mg/day) on homeostasis model assessment ratio (HOMA-R), an indicator resistance, 9 patients type 2 diabetes. The...