A5072410492- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Meta-analysis and systematic reviews
- Antifungal resistance and susceptibility
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Clinical Reasoning and Diagnostic Skills
- Sepsis Diagnosis and Treatment
- Hepatitis C virus research
- Pneumocystis jirovecii pneumonia detection and treatment
- Respiratory viral infections research
- Pharmaceutical Practices and Patient Outcomes
- Healthcare cost, quality, practices
- Medical Malpractice and Liability Issues
- Pneumonia and Respiratory Infections
- Delphi Technique in Research
- Liver Disease Diagnosis and Treatment
- Microbial infections and disease research
- Health Policy Implementation Science
- Methemoglobinemia and Tumor Lysis Syndrome
- Infective Endocarditis Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Bacterial Identification and Susceptibility Testing
- Neonatal Health and Biochemistry
- Hepatitis Viruses Studies and Epidemiology
- COVID-19 Clinical Research Studies
Weill Cornell Medicine
2018-2025
Cornell University
2018-2025
University of Minnesota Medical Center
2020
National Institute of Allergy and Infectious Diseases
2012-2016
National Institutes of Health
2012-2016
Systemic Candida albicans infection causes high morbidity and mortality is associated with neutropenia; however, the roles of other innate immune cells in pathogenesis are poorly defined. Here, using a mouse model systemic candidiasis, we found that resident macrophages accumulated kidney, main target organ infection, formed direct contacts fungus vivo mainly within first few hours after infection. Macrophage accumulation contact were both markedly reduced mice lacking chemokine receptor...
Invasive candidiasis is the 4th leading cause of nosocomial bloodstream infection in US with mortality that exceeds 40% despite administration antifungal therapy; neutropenia a major risk factor for poor outcome after invasive candidiasis. In fatal mouse model mimics human bloodstream-derived candidiasis, most highly infected organ kidney and neutrophils are cellular mediators host defense; however, factors regulating neutrophil recruitment have not been previously defined. Here we show mice...
CXCR1 as a mediator of neutrophil fungal killing and host defense against systemic infection in mice humans.
This Teachable Moment describes an 87-year-old man who underwent fatal complications from the use of benzocaine spray for nasopharyngeal anesthesia before insertion a nasogastric tube.
Scientific peer review has existed for centuries and is a cornerstone of the scientific publication process. Because number publications rapidly increased over past decades, so reviews reviewers. In this paper, drawing on relevant medical literature our collective experience as reviewers, we provide user guide to process, including discussion purpose limitations review, qualities good reviewer, step-by-step process how conduct an effective review.
BACKGROUND Point-of-care ultrasound (POCUS) is performed at the bedside by a healthcare professional who directly caring for patient. Subacute infective endocarditis can be challenging to diagnose, as patients often present with non-specific symptoms. The modified Duke criteria include echocardiographic findings major criterion, but role of POCUS has not been established. This report case diagnosed using POCUS. CASE REPORT A 57-year-old man was admitted hospital presumptive diagnosis rapidly...
The article examines infection with viral hepatitis A, B, and C socio-ethnic factors in a population of injection drug users seeking treatment. study was conducted between 2001 2003 rural German hospital; selected sociodemographic drug-related data as well serology for B were obtained from 1499 patients. Statistical analyses performed by univariate analysis variance post-hoc Scheffe tests or the c2-test Bonferroni-adjustment. Ethnic minority patients manifested more severe course addiction...