A5073387760- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Cell death mechanisms and regulation
- Nanoplatforms for cancer theranostics
- Functional Equations Stability Results
- Advanced Drug Delivery Systems
- Computability, Logic, AI Algorithms
- Metal complexes synthesis and properties
- Protein Degradation and Inhibitors
- Microtubule and mitosis dynamics
- Protein Interaction Studies and Fluorescence Analysis
- Palliative Care and End-of-Life Issues
- Limits and Structures in Graph Theory
- Fuzzy Systems and Optimization
- Brain Metastases and Treatment
- Bone Tissue Engineering Materials
- Chemotherapy-induced organ toxicity mitigation
- Optimization and Variational Analysis
- Lignin and Wood Chemistry
- Mathematical Inequalities and Applications
- Polyomavirus and related diseases
- DNA Repair Mechanisms
- Biochemical and Structural Characterization
- graph theory and CDMA systems
- Hops Chemistry and Applications
University of Delhi
1973-2025
Galgotias University
2025
Rajiv Gandhi Cancer Institute and Research Centre
2023
Creative Commons
2023
In this paper, we report the synthesis of bioactive copper-gallic acid nanoscale metal-organic framework for codelivery anticancer agent (gallic acid) and photosensitizer (methylene blue) to cancer cells. A supramolecular coordination complex copper-bioactive frameworks (bio MOFs) were employed as carrier two agents. The first one is natural phenolic acid), which forms a part structure (building block). other methylene blue, loaded guest molecule within amphiphilic pores framework. vitro...
Introduction: Quantum dots (QDs) are semiconductor nanocrystals with inherent fluorescence having several advantages over traditional fluorescent probes including their small size (5–10 nm), tunable excitation and emission spectra, ease of surface functionalization, robust photostability that makes them ideal candidates for in vivo imaging. The behavior QDs is highly dependent on the functionality. In toxicity biological systems major limitation hindering translation to clinics. Methods:...
This study investigates the asymmetric return-volatility relation for 21 major global market indices period 1998–2018, employing quantile regression methodology. The results show that transmission of good news shocks and bad has contrasting implications tails relation. During periods falling prices, sentiment-driven noise traders increase volatility levels. In contrast, during rising contrarian actions by more informed reduce Overall, support affect, representativeness, extrapolation bias...
Aim: To sensitize cisplatin (Cis)-resistant ovarian cancer cells toward Cis using Cis-loaded nanostructured lipid carriers (CisNLCs). Materials & methods: CisNLCs were synthesized and characterized dynamic light scattering, Fourier transform IR x-ray diffraction (XRD). Sensitivity of PA-1 CaOV3 to its biotoxicity assessed. Further, expression the Cis-resistance markers GSTPi ATP7B, apoptotic Bax, Bcl2 Cas9 quantified by real-time PCR. Results: The size was approximately 179.3 ± 2.32 nm...
Intravenously administered Etop formulations are quickly eliminated from the blood circulation and produce myelo-suppression, although effects of depend both on its concentration duration action [9], one most promising properties nanoparticles include their ability to act as carriers for different
Globally, breast cancer is the foremost cause of mortality among women detected with cancer, 21% diagnosed in India alone. Etoposide loaded gelatin nanoparticles (EGNP) were prepared and its physical characterization (size:150nm±0.241; zeta potential −29.32 mV) was done along in-vitro studies to assess biotoxicity, intracellular ROS, cell cycle arrest death caused by EGNPs. We report molecular pathways induced EGNP , pharmacokinetics, biodistribution tumor regression in-vivo Balb/c mice ....
Low aqueous solubility, adverse effects of Cisplatin includes hepatotoxicity and nephrotoxicity necessitates development nanoparticulate drug delivery. The study pertains to CisNLC (Cisplatin loaded Nanostructured Lipid Carrier) by ultrasonication. Physical characterisation particle size, zeta potential, TEM, SEM-EDX, DSC. Its ex vivo biocompatibility, pharmacokinetics biodistribution along with acute toxicity induced oxidative stress in Balb/c mice were evaluated. mean diameter was observed...
ABSTRACT Objective: This clinical study aimed to evaluate the psychosocial determinants influencing patients and caregivers seeking treatment at a tertiary cancer care center. Methods: The included 175 or (86 males 88 females) who visited hospital for checkups treatment. Data were collected using self-designed questionnaires. questionnaire assessed psychological issues, including anxiety, sleep, appetite, pain, fatigue, distress, depression, financial family social support, occupational...