A5048684488- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Lipoproteins and Cardiovascular Health
- Cardiac pacing and defibrillation studies
- Orthopaedic implants and arthroplasty
- Cancer, Lipids, and Metabolism
- Cardiac Structural Anomalies and Repair
- Cardiovascular Issues in Pregnancy
- Orthopedic Infections and Treatments
- Peripheral Artery Disease Management
- Regulation of Appetite and Obesity
- Hip disorders and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Fibrosis and Remodeling
- Aortic Disease and Treatment Approaches
- Neurological Disorders and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac and Coronary Surgery Techniques
- Pulmonary Hypertension Research and Treatments
- Sepsis Diagnosis and Treatment
- Bone health and osteoporosis research
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Acute Kidney Injury Research
- Cardiac Imaging and Diagnostics
Kemerovo State University
2017-2025
Research Institute of Complex Problems of Cardiovascular Disease Russian Academy of Medical Sciences
2016
Kemerovo State Medical Academy
2016
Highlights Acquired valvular heart disease (AVHD) is a widespread pathology that remains one of the leading causes cardiac mortality and disability in population. The article presents an analysis changes “portrait” patients undergoing surgical treatment AVHD. Aim. To assess from baseline characteristics with acquired mitral valve before implantation bioprosthetic valve. Methods . study included 600 admitted 2000–2020 AVHD using bioprosthesis produced domestically at Research Institute for...
Aim . To evaluate the effectiveness, safety, durability, and long-term outcomes of UniLine prosthetic valve application in patients with isolated mitral or aortic disease who have undergone a surgical replacement. Materials Methods The study aims to include at least 2,000 from seven Russian research centers replacement using an epoxy-treated, xenopericardial bioprosthetic UniLine. multicenter design enhances patient recruitment, ensures representative sample, minimises selection bias,...
The prevalence of familial hypercholesterolemia (FH) in Russia has not previously been evaluated. aim our study was to investigate the FH population West Siberian region Russia, and then estimate frequency coronary artery disease (CAD) treatment with cholesterol-lowering medication patients.The sample consisted participants from population-based cohort Epidemiology Cardiovascular Risk Factors Diseases Regions Russian Federation Study (ESSE-RF), conducted Tyumen Kemerovo regions (1,630 1,622...
РЕМОДЕЛИРОВАНИЕ МИОКАРДА ПРИ ПОРАЖЕНИЯХ КЛАПАНОВ СЕРДЦАО.К.Кузьмина, Н.В.Рутковская Научно-исследовательский институт комплексных проблем сердечно-
Highlights As evidenced in literature, mitral valve (MV) repair for regurgitation has many advantages, however, elderly patients have an extremely low risk of tissue degeneration, thus making the use this type surgery patient population controversial. Aim . To analyze role bioprostheses older age group undergoing replacement and compare results to outcomes. Methods The study included (over 65 years old) with who underwent annuloplasty using biological ring NeoRing (Neokor CJSC, Kemerovo) or...
Aim. To assess the occurence of hemodynamically non-significant multifocal atherosclerosis (from 30% and more), renal dysfunction their influence on outcomes in-hospital period patients underwent coronary bypass surgery (CABG). Material methods. The perioperational 720 analyzed, who were operated in 2011-2012 y. Before CABG all assessed by colored duplex scanning extracranial arteries lower extremities to reveal signs (MFA), also creatinine concentration was measured 1 day before 7 days...
Highlights. For the first time, as part of a prospective randomized study, comparative assessment mid-term results mitral valve annuloplasty using new biological NeoRing ring (CJSC NeoKor, Kemerovo) and RIGID NPP MedInzh, Penza) in patients with connective tissue dysplasia was carried out. Predictors conversion sinus rhythm to atrial fibrillation residual insufficiency medium-term follow-up period were determined. Aim. To analysis compare conducted и rings. Methods. From November 2019 March...
Aim. To study calcium-phosphor homeostasis and proinflammatory status of the cardiac valves bioprostheses (BP) recipients related to their interference with calcium degeneration biomaterials. Material methods. A retrospective assessment was performed metabolism markers non-specific inflammatory response in BP mitral position: histologically confirmed calcification — group I (n=22) normal morphology prosthesis function II (n=48). Results. In patients degeneration, comparing biological...
Aim. To study “the portrait” of patients with acquired mitral valve (MV) heart disease various origins and pulmonary hypertension hospitalized for surgical correction the defect. Methods. The included 97 diseases hypertension. assessment demographic, clinical anamnestic data, indicators transthoracic echocardiography, quality life before MV defect was carried out. Results. studied cohort is mostly represented by female (n = 70; 72.2%). most common cause rheumatic 40; 41.2%). Overweight, 76;...
Background . The matrix metalloproteinase (MMP) system and their tissue inhibitors (TIMPs) act to control myocardial remodeling processes. Aim. To evaluate serum levels of MMP-3, -9, TIMP-1, -2 relationships with instrumental parameters after isolated mitral valve replacement. Methods. All patients enrolled into the stenosis group (n = 24) insufficiency (n=24) underwent measurements by solid-phase enzyme immunoassay before replacement 1 year it. Results. Initial elevated MMP-9 correlated...
The development of the prediction methods calcification risk heart valve bioprostheses (BP) based on comprehensive assessment impact clinical factors recipients and their adherence to medication.We performed a retrospective study status drug therapy 170 BP with (n=63) without (n=109) calcification. We used method analyzed parameters estimation prognostic coefficients for each them, followed by calculation integral indicators construction basis models various intervals functioning.The most...
To assess significance of urinary neutrophil gelatinase-associated lipocalin (NGAL) for predicting hospital complications in subjects with ischemic heart disease (IHD) after coronary artery bypass grafting (CABG).The study included 720 who underwent CABG between 03/2011 and 04/2012. Blood serum creatinine level, glomerular filtration rate (GFR) (MDRD formula) NGAL concentration were measured before on day 7 CABG. The following unfavorable outcomes operative intervention: myocardial...
Aim. To study a bone mineral density (BMD) in recipients with calcium degeneration and preserved morphofunctional state of heart valve bioprotheses (BP). Material methods. The experimental groups included the patients structural dysfunctions BP associated calcification xenomaterial, confirmed by light electron microscopy data (group I, n=22) normal functional implanted valves according to results echocardiographic tests II, n=48). BMD was assessed dual energy absorptiometry absolute count...