A5061885085- Spectroscopy Techniques in Biomedical and Chemical Research
- Analytical Chemistry and Sensors
- Microfluidic and Capillary Electrophoresis Applications
- Neuroscience and Neural Engineering
- Electrochemical sensors and biosensors
- Microbial Fuel Cells and Bioremediation
- Biosensors and Analytical Detection
- Spectroscopy and Chemometric Analyses
- Electrochemical Analysis and Applications
- Plant-Derived Bioactive Compounds
- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Innovative Microfluidic and Catalytic Techniques Innovation
- Microfluidic and Bio-sensing Technologies
- Analog and Mixed-Signal Circuit Design
- Electrical and Bioimpedance Tomography
- Advanced Chemical Sensor Technologies
- Photoreceptor and optogenetics research
- Optical Imaging and Spectroscopy Techniques
- 3D Printing in Biomedical Research
- Electrowetting and Microfluidic Technologies
- Flow Measurement and Analysis
- Non-Invasive Vital Sign Monitoring
- Microwave and Dielectric Measurement Techniques
- Supercapacitor Materials and Fabrication
Université Laval
2016-2021
Centre of Excellence for Advanced Materials
2017
Abstract Strong control over experimental conditions in microfluidic channels provides a unique opportunity to study and optimize membraneless microbial fuel cells (MFCs), particularly with respect the role of flow. However, improved performance transferability results wider MFC community require improvements device stability under all applied operational conditions. To address these challenges, we present an easy‐to‐fabricate that combines i) O 2 protection via gas diffusion barrier, ii)...
In this paper, we present a new FTIR-based microfluidic system for Glucose, Fructose and Sucrose detection. The proposed is based on pseudo-continuous flow coupled to microscope-FTIR instrument. detection characterization of sugar samples were performed by recording their absorption spectrum in the wavelength range 700⁻1000 cm - 1 Mid-IR region. designed improve uniformity sample distribution analyzed area versus conventional systems. obtained results different sugars concentrations, show...
In this paper, we present a new modular lab on chip design for multimodal neurotransmitter (NT) sensing and niosome generation based plug-and-play concept. This architecture is first step toward an automated platform modulation of concentration to understand and/or treat neurodegenerative diseases. A approach has been adopted in order handle measurement or drug delivery both simultaneously. The system composed three fully independent modules: three-channel peristaltic micropumping system,...
A novel fully differential difference CMOS potentiostat suitable for neurotransmitter sensing is presented. The described architecture relies on a amplifier (FDDA) circuit to detect wide range of reduction-oxidation currents, while exhibiting low-power consumption and low-noise operation. This made possible thanks the feature FDDA, which allows increase source voltage swing without need additional dedicated circuitry. FDDA also reduces number amplifiers passive elements in design, lowers...
In this work, we present a new sensing approach for aqueous samples based on the microscope-FTIR spectrometer and applied neurotransmitters. Our contribution in work consists of sample handling system total reflective mirror, heated hydrophobic layer solvent removal/evaporation confinement microfluidic that handles injection unlike standard which was only mirror. addition, another part our proposing algorithm to extract molecular composition solution with high estimation ratios analysis...
In this work a new protocol based on FTIR-microspectrometry and solvent evaporation for neurotransmitter detection is presented. addition, automated sample handle support developed coupled to the microscope-FTIR in order perform Dopamine Ascorbic Acid sensing aqueous solutions. Results show that these molecules can be detected homogeneous mixture samples with different ratios of concentrations (Dopamine/Ascorbic Acid) varying from 4 0.25. Achieved limits was 3 μM 5 Acid, respectively, system...
Passing multiple light wavelengths through a blood sample makes it possible to investigate the presence and composition of cells, metabolytes analytes such as glucose, lactate oxygen, providing valuable indications for diagnostic health monitoring. In this paper, we present test prototype multi-wavelength spectroscopy platform integrated with microfluidic substrate collect convey samples series micro-LEDs photo-detector. This is proof concept system that can absorbance transmittance...
We present a four-channel, high-sensitivity and linearity electrochemical biosensor for neurotransmitter (NT) detection measurement. Using multi-channel microfluidic platform makes this capable of detecting NT-related currents going from nanoamperes to milliamperes, with sensitivity the order picoamperes. Moreover, by using fully differential potentiostat architecture, offers high common-mode rejection ratio (90 dB), making it appropriate low-noise high-sensitive applications. The system was...
Abstract Invited for this month's cover picture is the group of Jesse Greener at Laval University in Quebec City (Canada). The shows a real microfluidic microbial fuel cell (MFC) used study. Three graphical elements are superimposed to highlight critical design enhancements over previous literature examples. These include: i) improved anaerobic environment with an oxygen protection barrier, ii) robust and kinetically favorable graphite electrodes, iii) reduced anolyte/catholyte cross‐over...
In this work a new protocol based on Spectrophotometry and invertase solution for Sucrose quantification is presented. The molecule used releasing Glucose Fructose from molecules in maple syrup. Then, Oxydase (GO), Peroxydase (GPO), Phenol-4-sulfonic acid 4-aminoantipyrine are as the optical marker which will form colored compound. This coloration measured using technique then quantified. Finally glucose "standard" curve established after an optimization process of Trinder composition (GO,...
Modeling biological behaviour requires a multidisciplinary approach and very large computational resources. In this paper, we present an overview of our research work with regards to neuron network (NN) modeling, electrochemical reaction emulation for neurotransmitters finite element modeling (FEM) low pressure micropump neurotransmitter concentration modulations. Three different approaches have been explored, namely MATLAB simulations NN, electro-chemical reactions the FEM approach. Our...
This paper describes a proof of concept microfluidic dipole to sample cerebral fluid. It consists portable probe which injects buffer in one inlet and draws it from the other after passing through contact zone with external liquid. Finite elements method modelling (FEM) shows very stable liquid flow across complete probing area. Furthermore, we determined that design generating turbulence is likely be more useful capture brain molecules. Molecules displacement due diffusion phenomena takes...
In this work, we present a new microspectrometry FTIR-based biosensor for the analysis of sugar based solutions using various solvent and types sample handling support (SHS). We used methanol as because it does not interact with infrared (IR) beam. addition, ensures rapid evaporation in order to form thin layer targeted molecules on conventional SHS. The later consists total reflective mirror (TRM). Because toxicity, developed setup aqueous samples accelerated evaporation. achieved limit...
In this work, we propose a new multimodal method/platform for continuous maple syrup °Brix monitoring and color grading during the production process. It is based on different detection methods such as electrical impedance, electrochemical sensing optical sensing. First, using electrochemistry sensing, results of maximum detected current in obtained Voltammogram with cyclic-voltammetry (CV) analysis generated currents chronoamperometry experiments presents high standard deviation higher than...
Controlling micro-reactions is a challenge for researchers in biochemistry. The generation of microdroplets liquid plays an important role this field as it can be used regulating reactions well analysing them, with potential sensing and control applications. This work contributes to the integration microfluidic sample testing platforms such Lab-on-a-chip, by describing design simple microdroplet generator system that could implemented on purpose biological liquid's sampling. was first...