A5018387159- Origins and Evolution of Life
- Photoreceptor and optogenetics research
- Protein Structure and Dynamics
- Gene Regulatory Network Analysis
- Plant and Biological Electrophysiology Studies
- Evolutionary Game Theory and Cooperation
- Microbial Metabolic Engineering and Bioproduction
- Lipid Membrane Structure and Behavior
- Photosynthetic Processes and Mechanisms
- Philosophy and History of Science
- Space Science and Extraterrestrial Life
- Complex Systems and Decision Making
- Earth Systems and Cosmic Evolution
- Cognitive Science and Mapping
- Bioinformatics and Genomic Networks
- RNA Research and Splicing
- Embodied and Extended Cognition
- Social Representations and Identity
- Evolution and Science Education
- Slime Mold and Myxomycetes Research
- Polyamine Metabolism and Applications
- Evolution and Genetic Dynamics
- Lipid metabolism and biosynthesis
- Chaos, Complexity, and Education
- Cellular Automata and Applications
Instituto Biofisika
2017-2024
Fundación Biofísica Bizkaia
2017-2024
University of the Basque Country
2013-2023
Centre National de la Recherche Scientifique
2023
Institut d'Histoire et de Philosophie des Sciences et des Techniques
2023
Université Paris 1 Panthéon-Sorbonne
2023
Consejo Superior de Investigaciones Científicas
2010-2019
Donostia International Physics Center
2014
Roma Tre University
2006
Centro de Astrobiología
2004
Fatty acids, hypothetical components of protocell membranes, are proved to enhance the prebiotic formation a hydrophobic peptide when organized in supramolecular assemblies.
This paper is a theoretical attempt to gain insight into the problem of how self-assembling vesicles (closed bilayer structures) could progressively turn minimal self-producing and self-reproducing cells, i.e. interesting candidates for (proto)biological systems. With this aim, we make use recently developed object-oriented platform carry out stochastic simulations chemical reaction networks that take place in dynamic cellular compartments. We apply new tool study behaviour different cell...
In previous works we have explored the dynamics of chemically reacting proto-cellular systems, under different experimental conditions and kinetic parameters, by means our stochastic simulation platform 'ENVIRONMENT'. this paper we, somehow, turn question around: accepting some broad modeling assumptions, investigate which simple protocells will spontaneously settle into a stationary reproducing regime, characterized regular growth/division cycle maintenance certain standard size chemical...
Abstract The origin-of-life problem has been traditionally conceived as the chemical challenge to find type of molecule and free-solution reaction dynamics that could have started Darwinian evolution. Different autocatalytic ‘self-replicative’ molecular species extensively investigated, together with plausible synthetic pathways might led, abiotically, such a minimalist scenario. However, in addition kinetics or evolutionary dynamics, other physical constraints (like compartmentalization,...
We studied the properties of bilayers formed by ether-and ester-containing phospholipids, whose hydrocarbon chains can be either linear or branched, using sn-1,2 dipalmitoyl, dihexadecyl, diphytanoyl, and diphytanyl phosphatidylcholines (DPPC, DHPC, DPhoPC, DPhPC, respectively) pure in binary mixtures. Differential scanning calorimetry confocal fluorescence microscopy giant unilamellar vesicles concurred showing that equimolar mixtures branched lipids gave rise to gel/fluid phase coexistence...
In addressing the origins of Darwinian evolution, recent experimental work has been focussed on discovery simple physical effects which would provide a relevant selective advantage to protocells competing with each other for limited supply lipid. particular, data coming from Szostak's lab suggest that transition prebiotically plausible lipid membranes more complex and heterogeneous ones, closer real biomembranes, may have driven by changes in fluidity membrane its affinity available...