Hypertensive disorders of pregnancy, including chronic hypertension (CH) and preeclampsia (PE), stand as prominent global contributors to maternal perinatal morbidity mortality. Endothelial dysfunction plays a central role in the pathophysiology these conditions. This impacts blood flow regulation vascular response, potentially leading alterations remodeling vessels. Nitric oxide bioavailability, key regulator tone, is often diminished endothelial dysfunction, with nitrite levels serving...

Introduction: The manifestations of a sexually transmitted infection such as condyloma acuminatum generated by the HPV virus are reflected in increase prevalence curve women and men. Objective: To analyze effectiveness Imiquimod on anogenital warts immunocompetent Methods: search strategy was made PubMed, Scielo, LILACS Google Scholar, Scopus, Trip Database. only 13 articles entered. Results: Sauder et al, 2003 at 5%, efficacy men 72% 33% respectively. Baker 2011 2.5% 28.3%, 3.75% 36.6%....

This study aimed to investigate whether previous exercise training could prevent or attenuate acute cardiac alterations after myocardial infarction.Female rats were submitted swim (1 h/day; 5 days/week) allowed remain sedentary for 8 weeks. Afterwards, they randomly assigned left coronary artery occlusion sham surgery. After this procedure, the remained one week until euthanasia. Cardiac structural and functional analyses performed using Doppler echocardiography. The that had a moderate...

Few studies have analyzed the cardiac effects of exercise prior to coronary occlusion.To evaluate myocardial infarction in rats undergoing physical exercise.Female underwent swimming or were kept sedentary for eight weeks and randomized occlusion sham surgery, one following four groups: Sedentary (S), (E), (SMI) Exercise (EMI). After six weeks, their biometrics, Doppler echocardiography, hemodynamics mechanics analyzed.No cardioprotection was observed EMI animals there no difference infarct...

Background: There is little research in the efficacy and safety of a pharmaco-invasive strategy (PIS) patients ≥ 75 years versus < age. We aimed to evaluate compare influence advanced age on risk death major adverse cardiac events (MACE) undergoing PIS. Methods: Between January 2010 November 2016, 14 municipal emergency rooms São Paulo, Brazil, used full-dose tenecteplase treat with STEMI as part for local network implementation. Results: A total 1852 PIS were evaluated, which 160 (9%)...

Precocious puberty (PP) is defined as premature pubertal development. Its consequences surpass the physical evidence of sexual maturity with epiphyseal closure long bones and reduction adult stature by varied degrees. Central PP characteristically dependent on GnRH most its causes are not completely known. Altered estrogen action also believed to be involved in genesis PP. In fact, receptor alpha (Rea) gene polymorphisms may associated early age at menarche. The objective this study was...

To assess the knowledge of students from public high schools in poor communities about HPV and Sexually Transmitted Infections their attitude towards prevention such diseases. Cross-sectional study with adolescents São Paulo – Brazil. Participants were selected for an interview by a randomization program. A questionnaire knowledge, attitudes, preventive practices regarding STIs, including HPV, according to sex was administered answers analyzed Poisson regression model robust variance. Median...

The ability to predict reward and punishment is essential for decision-making the learn about an ever-changing environment. Therefore, efforts have been made in understanding mechanisms underlying decision-making, especially regarding how affective deliberative processes interact with risk behavior.To adapt Brazilian Portuguese Columbia Card Task (CCT) investigate involved decision-making.This study had two main phases: (1) a transcultural adaptation (2) pilot study.The feedback manipulation...

SUMMARY OBJECTIVE The aim of this study was to evaluate gynecological cancer and metabolic screening Brazilian women aged 65 years or older. METHODS This retrospective descriptive conducted by including 1,001 patients the geriatric outpatient office our institution influence age on parameters at first clinical visit. All were divided into three groups: a) 69 years; b) 70 74 c) ≥ 75 years. We considered clinical, laboratorial, image data as variables study. Chi-square test used assess...

Abstract Objectives: This study aimed to evaluate the effects of acupuncture on women with vasomotor symptoms during menopausal transition aid Kupperman-Blatt Menopausal Index. Method: Crossover, single-blind, sham-controlled trial 100 randomly divided into two groups 50 participants each: G1 and G2. During first 24 weeks treatment, received G2 were given sham acupuncture. The crossover was then applied: acupuncture, for more weeks. Results: mean score hot flashes group who experienced (G1)...

To assess the quality of life hospitalized pregnant women with preeclampsia (PE), and compare a group healthy (HP). This was an observational cross-sectional study conducted among 58 women; 28 them had 30 were healthy. The WHOQOL-Bref questionnaire, which divided into four aspects: physical, psychological, social, environmental, applied to each subject. A statistically significant difference observed regarding maternal age (PE 27.8±6.2 x HG 23.0±6.6, p<0.01) gestational 224±28.1 253.8±43.7,...

A prospective cohort study was conducted on a convenience sample of 1370 pregnant women with gestational age 20 to 25 weeks in the city Ribeirão Preto. Data obstetrical history, maternal age, parity, smoking habit, and history preterm delivery collected application sociodemographic questionnaire. Cervical length determined by endovaginal ultrasound, urine vaginal content samples were obtained determine urinary tract infection (UTI) bacterial vaginosis (BV), respectively. The aim this verify...

The present study aimed to analyze the effects of reperfusion a distant coronary artery on cardiac function, ultrastructure, and molecular environment remote myocardium immediately after completion myocardial regional necrosis: delayed (DR). Additionally, prior exercise outcomes DR were investigated. Female rats with permanent occlusion or randomly assigned an (swimming, 1 h/day, 5 days/week for 8 weeks) sedentary protocol. Thus, included following four groups: occlusion, reperfusion,...

Gestational hypertension and pre-eclampsia are important causes of perinatal morbidity. The objective the present study was to determine increase in relative risk for developing hypertensive disorders pregnancy based on evaluation pregnant women between 20 25 weeks gestation, correlate findings at this period with outcome pregnancy. We conducted a prospective cohort study, convenience sample 1417 patients evaluated gestational age, which 1306 were contacted childbirth. detected an increased...