A5041097950- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Phenothiazines and Benzothiazines Synthesis and Activities
- Ethnobotanical and Medicinal Plants Studies
- Synthesis and Characterization of Heterocyclic Compounds
- Luminescence Properties of Advanced Materials
- Consumer Attitudes and Food Labeling
- Synthesis of Tetrazole Derivatives
- Corrosion Behavior and Inhibition
- Electronic and Structural Properties of Oxides
- Moringa oleifera research and applications
- Synthesis of Organic Compounds
- Food Safety and Hygiene
- Magnetic and transport properties of perovskites and related materials
- Cancer therapeutics and mechanisms
- Essential Oils and Antimicrobial Activity
- Hydrogen embrittlement and corrosion behaviors in metals
- African Botany and Ecology Studies
- Probiotics and Fermented Foods
- Concrete Corrosion and Durability
- Synthesis and Biological Evaluation
Covenant University
2016-2019
Quinoline is a benzo‐fused pyridine which therapeutically important heterocycle in medicinal chemistry research and new drug development. A series of 12 hydrazide‐hydrazone motifs bearing quinoline core 4a–l was successfully synthesized by microwave irradiation technique. The synthesis involved four steps strategies initiated ring‐opening synthetic modification isatin to quinoline‐4‐carboxylic acid through Pfitzinger approach. structure the reactive intermediates 1, 2, 3 as well targeted...
Oriental Journal of Chemistry is a peer reviewed quarterly research journal pure and applied chemistry. It publishes standard papers in almost all thrust areas current chemistry academic commercial importance. provides platform for rapid publication quality papers, reviews letters. abstracted indexed reputed National International agencies.
The aim of this present study was to synthesize 2-substituted and 1,2-disubstituted benzimidazole derivatives investigate their antibacterial diversity for possible future drug design. structure-based design precursors 2-(1H-benzimidazol-2-yl)aniline 1, 2-(3,5-dinitro phenyl)-1H-benzimidazole 3 2-benzyl-1H-benzimidazole 5 were achieved by the condensation reaction o-phenylenediamine with anthranilic acid, 3,5-dinitrophenylbenzoic phenylacetic respectively. 5, upon six different...
Microwave-assisted approach was utilized as green to access a series of 2-propylquinoline-4-carbohydrazide hydrazone derivatives 10a-j aromatic and heteroaromatic aldehydes in highly encouraging yields. It involved four steps reaction which initiated with ring opening isatin basified environment subsequent cross-coupling pentan-2-one produce compound 7. Esterification 7 acid medium led the formation 8 reacted hydrazine hydrate 9 upon microwave-assisted condensed furnished targeted compounds...
Phytochemical and antibacterial properties of ethanolic extract the seeds African Star Apple (Chrysophyllum albidum) were investigated. The phytochemical result revealed presence saponins, carbohydrates, flavonoids, quinones, cardiac glycosides, fatty acids terpenoids. activity was studied using agar well diffusion method at different concentrations against six pathogenic bacterial strains, three Gram-positive (Staphylococcus aureus, Micrococcus varians Bacillus cereus) Gram-negative...
Ten authorized Yogurt products purchased within Ota metropolis, Ogun State of Nigeria were subjected to pH, Total Bacterial Count (TBC) and Fungal (TFC) analysis. pH values in the range 4.05 5.50, TBC TFC ranged between 1.0 × 103 − 5.0 105 cfu/ml respectively. Eleven bacterial isolates detected yogurt samples. Lactobacillus spp. Bacillus constituted 16% total microbial load, Corynebacterium spp., Klebsiela Staphylococcus Pseudomonas 8% while Proteus Micrococcus Shigella Listeria...
A variety of 3-(5-(substituted-phenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives 3a–j were synthesized through microwave assisted thermal annulation corresponding α,β-unsaturated ketones (chalcones) 2a–j via hydrazinolysis. Chalcones prepared from 3-acetyl-coumarin 1 which was previously accessed by Pechmann condensation reaction salicylaldehyde. The series pyrazoline-based coumarin motifs synthesized, structurally confirmed analytical and spectral data. They then evaluated...
We report the structural, morphological and optical activities of a paramagnetic manganite (La0.33Ca0.67MnO3) synthesized at 900 °C. A simple method formation complex was employed. formed between pre-prepared dissolved in HCl reacted with an organic ligand (ethyl 4-nitrobenzoate). The antimicrobial properties were determined. Ultraviolet-visible Fourier-transform infra-red spectroscopy used monitoring resulting product. It observed to absorb visible region (205 nm 256 nm). peaks from spectra...
A series of functionalized 2-substituted benzimidazole motifs was designed and successfully synthesized via thermal cyclization 1,2-diaminobenzene on COOH end L- leucine to achieve derivatives 6 as the essential precursor. The coupling precursor with benzaldehyde a-h, ketone i-k, aryl sulfonyl chlorides l-n led formation targeted 7a-n in improved yields. were structurally authenticated through their spectral data microanalytical parameters. final moieties investigated for potential...