A5073877765- Advances in Cucurbitaceae Research
- Ginseng Biological Effects and Applications
- Toxin Mechanisms and Immunotoxins
- Natural product bioactivities and synthesis
- Bioactive Compounds and Antitumor Agents
- Protein Tyrosine Phosphatases
- Nanoparticle-Based Drug Delivery
- Endometrial and Cervical Cancer Treatments
- Biological Activity of Diterpenoids and Biflavonoids
- Gastric Cancer Management and Outcomes
- Axon Guidance and Neuronal Signaling
- Plant Molecular Biology Research
- Peptidase Inhibition and Analysis
- PI3K/AKT/mTOR signaling in cancer
- Colorectal Cancer Treatments and Studies
- Yeasts and Rust Fungi Studies
- Monoclonal and Polyclonal Antibodies Research
- Mycotoxins in Agriculture and Food
- Plant-Microbe Interactions and Immunity
- Potato Plant Research
- Phytoestrogen effects and research
- Plant Pathogens and Fungal Diseases
Jilin University
2019-2023
Lung cancer is the leading cause of death in world and classified into non-small cell lung (NSCLC) small (SCLC). As tyrosine kinase inhibitors (TKIs), several triterpenoid saponins can target to epidermal growth factor receptor (EGFR), a widely used molecular therapeutic target, exhibit remarkable anti-proliferative activities cells. one saponins, 20([Formula: see text])-ginsenoside Rg3 [20([Formula: text])-Rg3] was confirmed be an EGFR-TKI this work. According quantitative real-time reverse...
Mycotoxins contribute considerably to food losses and pose serious health risks humans animals. This study investigated the mechanisms underlying elimination of mycotoxin zearalenone (ZEN) by a yeast strain, Rhodotorula dairenensis ZDY342B, which was isolated from feces ZEN-treated mice. Isotope-labeled 13C18-ZEN employed for accurately tracking degradation products ZEN, chemical composition cells characterized before after ZEN elimination. The results these analyses confirmed that strain...
Cucurbitacins, widely found in plants belonging to the family of Cucurbitaceae, are highly oxidized tetracyclic triterpenes with various bioactivities, such as anticancer, anti-inflammatory, and liver protection. Among which, anticancer activity cucurbitacins is well studied. Cucurbitacins have been reported promote apoptosis through JAK/STAT3 pathway MAPK pathway. can block cell cycle by inhibiting cyclins. They also accelerate autophagy inhibit invasion migration cancer cells. Numerous...
Transferrin receptor (TfR) is a glycoprotein that transfers iron from the extracellular matrix to intracellular environment. Due rapid proliferation need, demand for in cancer cells much greater than normal cells, possibly explaining upregulated TfR expression cells. The overexpression of and its accessibility, ability internalize, central role cell make this potential target antibody-mediated therapy. can be targeted indirectly by antibodies conjugated anti-cancer agents or directly through...
Apples are deeply loved by people because of their rich nutritional value, but they susceptible to rotting. The use antagonistic yeast is a promising method for controlling postharvest fruit diseases, biocontrol efficacy will be weakened in environmental stress. In this study, the effects glycine (Gly) on oxidative stress tolerance and Sporidiobolus pararoseus (S. pararoseus) against Aspergillus niger (A. niger) discussed. Under stimulation H2O2, cells treated with Gly (1 mM) showed lower...
The objectives of this study was to examine the role transferrin receptor (TfR) in treatment cervical cancer. Demographic and cancer-specific data were collected prospectively. Cancerous adjacent mucosa tissues with neoadjuvant chemotherapy (NACT) or surgery alone collected. TfR mRNA protein expression measured by Quantitative reverse transcription PCR (RT-qPCR) immunoblots. We cell viability MTT (3- [4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay without TfR-siRNA...