Sophia Hu

ORCID: 0000-0002-0191-4301
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About
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Research Areas
  • Cancer-related gene regulation
  • RNA Interference and Gene Delivery
  • Carbohydrate Chemistry and Synthesis
  • Patient Safety and Medication Errors
  • Geriatric Care and Nursing Homes
  • Aging and Gerontology Research
  • Simulation-Based Education in Healthcare
  • Pharmaceutical Practices and Patient Outcomes
  • Health disparities and outcomes
  • Diabetes Management and Education
  • Retinoids in leukemia and cellular processes
  • Dementia and Cognitive Impairment Research
  • Wound Healing and Treatments
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Nutrition and Health in Aging
  • Histone Deacetylase Inhibitors Research
  • Healthcare professionals’ stress and burnout
  • Nursing education and management
  • Nursing Roles and Practices
  • Palliative Care and End-of-Life Issues
  • Diabetes Management and Research
  • Medication Adherence and Compliance
  • Clinical Reasoning and Diagnostic Skills
  • Thyroid Cancer Diagnosis and Treatment
  • Global Health Workforce Issues

National Yang Ming Chiao Tung University
2015-2025

Brigham and Women's Hospital
2024-2025

Harvard University
2024-2025

Johns Hopkins Medicine
2023

Johns Hopkins University
2023

University of Baltimore
2023

University of Pennsylvania
2022

Creative Commons
2022

Taipei Medical University
2014-2019

Case Western Reserve University
2014-2016

Abstract Context Guidelines for use of injectable estradiol esters (valerate [EV] and cypionate [EC]) among transgender gender diverse (TGD) individuals designated male at birth vary considerably, with many providers noting supraphysiologic serum concentrations based on current dosing recommendations. Objectives 1. Determine dose (subcutaneous [SC] intramuscular [IM]) needed to reach guideline-recommended TGD adults using EC/EV. 2. Describe relationship between concentration relative...

10.1210/clinem/dgaf015 article EN publisher-specific-oa The Journal of Clinical Endocrinology & Metabolism 2025-01-09

Background: To investigate the effects of personalized DiaBetes TEXT messaging combined with Peer Support Education (DB-TEXT+ PSE) on clinical outcomes in patients type 2 diabetes. Methods: An assessor-blinded, three-arm randomized controlled trial recruited 84 participants between December 2022 and July 2023. Participants were randomly assigned to a DB-TEXT + PSE group, or professional education program (PEP) group. Primary included glycated hemoglobin (HbA 1c ), fasting blood glucose (FBG)...

10.1177/19322968251314501 article EN Journal of Diabetes Science and Technology 2025-01-29

Aims and objectives To investigate the relationship of nurse practitioners’ social support as well other factors associated with perceived self‐efficacy. Background There is a growing demand for practitioners in Taiwan, whom self‐perceived efficacy performance. Nevertheless, research on self‐efficacy limited. Design This cross‐sectional survey study. Methods Questionnaires were distributed to seven hospitals northern Taiwan from May 2015 March 2016. In total, data 335 (78% return rate)...

10.1111/jocn.14129 article EN Journal of Clinical Nursing 2017-10-27

To investigate the knowledge of and attitudes towards palliative care for advanced dementia their associations with demographics among nursing staff, including nurses assistants, in long-term settings.Nursing facilities are places where persons die; therefore, providing quality end-of-life to residents is crucial. date, little attention has been paid practice patients dementia.A descriptive, cross-sectional, survey design was used.In total, a sample 300 (n = 125) assistants 175) working...

10.1111/jocn.14132 article EN Journal of Clinical Nursing 2017-10-27

Abstract Mdm2, an E3 ubiquitin ligase, negatively regulates the tumour suppressor p53. In this study we utilized a conditional Mdm2 allele, FM , and CAG–CreER tamoxifen‐inducible recombination system to examine effects of global loss in adult mice. Two different tamoxifen injection regimens caused 100% lethality /− ; mice; both radio‐sensitive radio‐insensitive tissues were impaired. Strikingly, large number tissues, including kidney, liver, heart, retina hippocampus, exhibited various...

10.1002/path.4368 article EN The Journal of Pathology 2014-04-30

Standard therapies used for the treatment of acute myeloid leukemia (AML) are cytotoxic agents that target rapidly proliferating cells. Unfortunately, this therapeutic approach has limited efficacy and significant toxicity majority AML patients still die their disease. In contrast to poor prognosis most patients, individuals with a rare subtype AML, promyelocytic leukemia, can be cured by differentiation therapy using regimens containing all-trans retinoic acid. GSK3 been previously...

10.1158/1535-7163.mct-15-0566 article EN Molecular Cancer Therapeutics 2016-05-10

Loneliness has become one of the most common psychological problems experienced by older adults. Previous studies have indicated that loneliness is correlated with poor physical and health outcomes; therefore, it important to pay attention people experiencing loneliness. However, there a lack information regarding prevalence loneliness, its associated factors, among community-dwelling adults in Indonesia, which this study aimed understand. This used cross-sectional, descriptive,...

10.3390/ijerph19084911 article EN International Journal of Environmental Research and Public Health 2022-04-18

Loneliness is a negative emotional feeling often experienced by older residents in long-term care facilities (LTCFs). Previous studies have shown that loneliness related to depression, inferior quality of life, cardiovascular disease, and suicidal thoughts. Thus, it important understand residents' viewpoints about provide better the context. This study aimed explore perceptions LTCFs. For this qualitative research, data were collected from two LTCFs northern Taiwan, purposive sampling was...

10.1111/inm.12979 article EN International Journal of Mental Health Nursing 2022-02-03

The study aimed to explore and compare stress, coping, professional identity work locus of control new graduate nurses among Shanghai, Hong Kong Taipei.The transition from a student staff nurse role is recognized as stressful experience can be rough journey. Many newly graduated find it challenging cope with their roles in first few months.A cross-sectional research was used the study. This completed Taipei working hospitals. A total 591 who had worked within 1 year hospitals were recruited...

10.1111/jonm.13801 article EN Journal of Nursing Management 2022-09-30

In Indonesia, the number of Type 2 diabetes cases is increasing rapidly, making it third leading cause death and among noncommunicable disease healthcare expenditures in country. Thus, there a critical need for Indonesians with to perform better self-care optimize their health prevent onset comorbidities.

10.1097/jnr.0000000000000601 article EN cc-by Journal of Nursing Research 2024-02-26

Abstract Hypertrophic scarring is a major source of morbidity. Sex hormones are not classically considered modulators scarring. However, based on increased frequency hypertrophic in patients testosterone, we hypothesized that androgenic steroids induce abnormal and developed preclinical porcine model to explore these effects. Mini‐swine underwent castration, received no testosterone (noT) or biweekly therapy (+T), excisional wounding. To create delayed wound healing model, subset wounds were...

10.1096/fj.202302144rrr article EN The FASEB Journal 2024-03-26

To compare perceptions of various aspects palliative care for doctors and nurses; examine factors contributing to perceived quality in intensive units (ICUs).A cross-sectional survey study conducted from November December 2013. Questionnaires used were Knowledge, Attitudinal Experiential Survey on Advance Directives (ADs), Clarke's Quality Palliative Care Nurses' Participation the end-of-life (EOL) decision-making process.Seven adult medical surgical ICUs at a center Northern Taiwan.In...

10.1093/intqhc/mzz003 article EN International Journal for Quality in Health Care 2019-01-28

ABSTRACT The investigators aimed to explore the prevalence of depressive symptoms and associated factors among older residents with intact cognitive function in nursing homes Taiwan. A cross‐sectional descriptive correlational research design was used. convenience sample 178 without impairment recruited from 36 Southern questionnaires included demographic data; Barthel Index, which assesses ability perform activities daily living; Geriatric Depression Scale Short Form. Among function, 39.3%...

10.1002/nur.21873 article EN Research in Nursing & Health 2018-03-25
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