A5016230515- Diet and metabolism studies
- Alcohol Consumption and Health Effects
- Neurotransmitter Receptor Influence on Behavior
- Hormonal and reproductive studies
- Peroxisome Proliferator-Activated Receptors
- Stress Responses and Cortisol
- Veterinary Pharmacology and Anesthesia
- Neuroscience and Neural Engineering
- Veterinary Equine Medical Research
- Pharmacological Effects and Assays
University of New Mexico
2022
LAC+USC Medical Center
1990
The University of Texas Health Science Center at San Antonio
1981
The Ohio State University
1980
Abstract Background Excessive alcohol (ethanol) consumption, such as binge drinking, is extremely commonplace and represents a major health concern. Through modeling excessive drinking in rodents, we are beginning to uncover the neurobiological neurobehavioral causes consequences of this pattern ethanol intake. One important factor for mice that they reliably drink blood concentrations (BECs) 80 mg/dl or higher. Drinking‐in‐the‐dark (DID) commonly used mouse model have shown method results...
In immature (30–35-day-old) mice, a single dose of Δ9-tetrahydrocannabinol (THC), the main psychoactive constituent marihuana, decreased plasma testosterone (T), LH, and FSH levels, but same nonpsychoactive component, cannabinol (CBN), had no effect. Chronic exposure to THC, CBN, or cannabidiol (CBD), beginning at 30 days age through adulthood, influenced endocrine responses sexually receptive female. Thus, weights testes seminal vesicles were reduced in males from all cannabinoid-treated...
SUMMARY The acute behavioral cardiopulmonary and pharmacokinetic effects of propoxyphene hydrochloride were studied in seven adult horses. Each horse was given three different dosages (0.5, 1.0, 2.2 mg/kg) iv . Fourteen days allotted between each drug administration. lower 1.0 resulted no changes indices function. Four horses demonstrated a transient period muscle fasciculations when 0.5 mg propoxyphene/kg. Horses mg/kg brief euphoria, ataxia, followed by increased motor activity lasting for...
Joseph, M. M.D.; Lew, M.; Fortney, P.; Bandari, B.; Pearson, E.; Huffman, R. Author Information