A5044955721- Glioma Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Nanoparticle-Based Drug Delivery
- Cerebrospinal fluid and hydrocephalus
- Brain Metastases and Treatment
- Meningioma and schwannoma management
- Advanced Radiotherapy Techniques
- Intracerebral and Subarachnoid Hemorrhage Research
- Photonic and Optical Devices
- Neurological Disease Mechanisms and Treatments
- Pituitary Gland Disorders and Treatments
- Luminescence Properties of Advanced Materials
- Neurological Complications and Syndromes
- Intestinal Malrotation and Obstruction Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- RNA Interference and Gene Delivery
- Neurofibromatosis and Schwannoma Cases
- Photoacoustic and Ultrasonic Imaging
- Luminescence and Fluorescent Materials
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Issues in Pregnancy
- Assisted Reproductive Technology and Twin Pregnancy
National University Hospital
2020-2024
National University Health System
2021
National University of Singapore
2016
Acharya Nagarjuna University
2016
Abstract Near‐infrared (NIR) activatable upconversion nanoparticles (UCNPs) enable wireless‐based phototherapies by converting deep‐tissue‐penetrating NIR to visible light. UCNPs are therefore ideal as wireless transducers for photodynamic therapy (PDT) of deep‐sited tumors. However, the retention unsequestered in tissue with minimal options removal limits their clinical translation. To address this shortcoming, biocompatible implants developed deliver photonic properties a flexible, optical...
External ventricular drain (EVD) placement is the gold standard for managing acute hydrocephalus. Freehand EVD, using surface anatomical landmarks, performed cannulation due to its simplicity and efficiency. This study evaluates accuracy reason(s) misplacements as few studies have analyzed of freehand EVD insertion.Preoperative postoperative computed tomography scans patients who underwent insertion in 2014 were retrospectively reviewed. Diagnosis, Evans ratio, midline shift, position burr...
Moyamoya disease (MMD) is an incompletely understood malady that affects many age groups, primarily in a bimodal distribution. We present patient with the association of type 1 diabetes mellitus (type DM) and MMD followed by review existing literature. found five papers describe this association, form one case report, series, three retrospective reviews. Despite poor understanding underlying pathophysiology, clear between autoimmune conditions appears to exist. Clinicians who manage such...
High grade astrocytic glioma (HGG) is a lethal solid malignancy with high recurrence rates and limited survival. While several cytotoxic agents have demonstrated efficacy against HGG, drug sensitivity testing platforms to aid in therapy selection are lacking. Patient-derived organoids (PDOs) been shown faithfully preserve the biological characteristics of cancer types including coupled experimental-analytical hybrid platform Quadratic Phenotypic Optimization Platform (QPOP) which evaluates...
An upconversion biocompatible implant is the first step of translating decades-old near-infrared nanotransducer research into wireless phototherapeutic devices that can be implanted underneath skin. The use a hydrogel and cladding results in an optical fiber able to upconvert flexible manner even transmit NIR at maximal bending described by Kah-Leong Lim, Yong Zhang, Brian K. Kennedy, co-workers article number 2001459. This concept applicable various needs phototherapeutics. With better...
Abstract INTRODUCTION External ventricular drain (EVD) placement is the gold standard for managing acute hydrocephalus. Freehand EVD, using surface anatomical landmarks performed cannulation due to its simplicity and efficiency. This study evaluates accuracy reason(s) misplacements as few studies have analyzed of freehand EVD insertion. METHODS Preoperative postoperative computed tomography (CT) scans patients who underwent insertion in 2014 were retrospectively reviewed. Diagnosis, Evan's...
Background and Objective: The role of superficial temporal artery-middle cerebral artery (STA-MCA) bypass in patients with symptomatic intracranial steno-occlusive disease has been evaluated scarcely. We have recently reported the improvement clinical various hemodynamic parameters after STA-MCA surgery for severe internal carotid (ICA) or middle (MCA) impaired vasodilatory reserve (CVR). Using acetazolamide challenged hexamethylpropyleneamine-oxime single-photon emission computed tomography...