- Theoretical and Computational Physics
- Magnetic properties of thin films
- Quantum many-body systems
- Marine Sponges and Natural Products
- Marine Toxins and Detection Methods
- Magnetism in coordination complexes
- Microbial Natural Products and Biosynthesis
- Molecular spectroscopy and chirality
- Plant Micronutrient Interactions and Effects
- Plant Stress Responses and Tolerance
- Magnetic Properties and Applications
- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Analysis
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Plant biochemistry and biosynthesis
- Advanced NMR Techniques and Applications
- Physics of Superconductivity and Magnetism
- Chemical synthesis and alkaloids
- Opinion Dynamics and Social Influence
- Advanced Condensed Matter Physics
- Synthesis and Biological Evaluation
- Porphyrin and Phthalocyanine Chemistry
- Legume Nitrogen Fixing Symbiosis
- Aluminum toxicity and tolerance in plants and animals
Suntory Foundation for Life Sciences
2008-2018
Kyushu Tokai University
1997-2012
Suntory (Japan)
1983-2012
Tohoku University
1988-2012
Kwansei Gakuin University
2009-2012
Osaka City University
2009-2012
Osaka University of Pharmaceutical Sciences
1992-2010
Toyama Prefectural University
2003-2010
Institute for Materials Research, Tohoku University
2010
University of Amsterdam
2007-2010
The pathogenesis of Alzheimer's disease is characterized by the aggregation and fibrillation 40-residue A beta(1-40) 42-residue beta(1-42) peptides into amyloid plaques. structural changes associated with conversion monomeric beta peptide building blocks multimeric fibrillar beta-strand aggregates remain unknown. Recently, we established that oxidation methionine-35 side chain to sulfoxide (Met35(red) --> Met35(ox)) significantly impedes rate peptide. To explore this effect at greater...
Fifty-four polyphenols isolated from tea leaves were evaluated for their inhibitory activities against pancreatic lipase, the key enzyme of lipid absorption in gut. (-)-Epigallocatechin 3-O-gallate (EGCG), which is one major green tea, showed lipase inhibition with an IC50 0.349 microM. Moreover, flavan-3-ol digallate esters, such as (-)-epigallocatechin-3,5-digallate, higher on 0.098 On other hand, nonesterified flavan-3-ols, (+)-catechin, (-)-epicatechin, (+)-gallocatechin, and...
An internal detoxification mechanism for Al was investigated in an Al-accumulating plant, hydrangea (Hydrangea macrophylla), focusing on forms present the cells. The leaves of contained as much 15.7 mmol kg-1 fresh weight, and more than two-thirds found cell sap. Using 27Al- nuclear magnetic resonance, dominant peak observed at a chemical shift 11 to 12 parts per million both intact extracted sap, which is good accordance with 1:1 Al-citrate complex. Purification sap by molecular sieve...
Summary Iron acquisition of graminaceous plants is characterized by the synthesis and secretion iron‐chelating phytosiderophore, mugineic acid (MA), a specific uptake system for iron(III)–phytosiderophore complexes. We identified gene specifically encoding an iron–phytosiderophore transporter (HvYS1) in barley, which most tolerant species to iron deficiency among plants. HvYS1 was predicted encode polypeptide 678 amino acids have 72.7% identity with ZmYS1, first protein as maize. Real‐time...
Abstract Rice (Oryza sativa L. cv Oochikara) is a typical silicon-accumulating plant, but the mechanism responsible for high silicon uptake by roots poorly understood. We characterized system in rice using low-silicon mutant (lsi1) and wild-type rice. A kinetic study showed that concentration of root symplastic solution increased with increasing concentrations external saturated at higher both lines. There were no differences between mutant. The form soluble root, xylem, leaf identified...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure of maitotoxinMichio Murata, Hideo Naoki, Takashi Iwashita, Shigeki Matsunaga, Masahiro Sasaki, Akihiro Yokoyama, and Takeshi YasumotoCite this: J. Am. Chem. Soc. 1993, 115, 5, 2060–2062Publication Date (Print):March 1, 1993Publication History Published online1 May 2002Published inissue 1 March 1993https://pubs.acs.org/doi/10.1021/ja00058a075https://doi.org/10.1021/ja00058a075research-articleACS PublicationsRequest reuse permissionsArticle...
Rice (Oryza sativa L.) is a typical silicon (Si)-accumulating plant, but the mechanism responsible for translocation from root to shoot poorly understood. In this study, form of Si in xylem sap was identified by 29Si-nuclear magnetic resonance (NMR) spectroscopy. rice (cv. Oochikara) cultured monosilicic acid solution containing 0.5 mM Si, concentration reached 6 within 30 min. 29Si-NMR spectra sap, only one signal observed at chemical shift –72.6 ppm, which consistent with that acid. A...
Arabidopsis halleri is a Cd hyperaccumulator; however, the mechanisms involved in root to shoot translocation of are not well understood. In this study, we characterized transfer from medium xylem species. accumulated 1,500 mg kg(-1) without growth inhibition. A time-course experiment showed that release into was very rapid; by 2 h exposure Cd, concentration sap 5-fold higher than external solution. The increased linearly with increasing completely inhibited metabolic inhibitor carbonyl...
Journal Article Some Chemical Properties of Maitotoxin, a Putative Calcium Channel Agonist Isolated from MarineDinoflagellate Get access Akihiro Yokoyama, Yokoyama *Department Food Chemistry, Faculty Agriculture, Tohoku UniversitySendai, Miyagi 980 Search for other works by this author on: Oxford Academic PubMed Google Scholar Michio Murata, Murata Yasukatsu Oshima, Oshima Takashi Iwashita, Iwashita Takeshi Yasumoto 2 **Suntory Institute Bioorganic Research, Shimamoto-choMishima-gun, Osaka...
In contrast to the wealth of biochemical and genetic information on vertebrate glucuronosyltransferases (UGATs), only limited is available role phylogenetics plant UGATs. Here we report purification, characterization, cDNA cloning a novel UGAT involved in biosynthesis flower pigments red daisy (<i>Bellis perennis</i>). The purified enzyme, BpUGAT, was soluble monomeric enzyme with molecular mass 54 kDa catalyzed regiospecific transfer glucuronosyl unit from UDP-glucuronate 2″-hydroxyl group...
(+)-Sesaminol 2-O-triglucoside is the most abundant water-soluble furofuran lignan in sesame seeds (Sesamum indicum) and considered to be a beneficial compound for human health. The biosyntheses physiological roles of glycosides, however, remain elusive. Here we report molecular identification biochemical characterization two Sesamum uridine diphosphate (UDP) glucose:lignan glucosyltransferases. indicum UGT71A9 preferentially glucosylated at 2-hydroxyl group (+)-sesaminol, resulting...
Ionic aluminum (Al) is toxic for plant growth, but some species are able to accumulate Al at high concentrations without showing toxicity symptoms. In order determine whether other in the genus Fagopyrum like common buckwheat (Fagopyrum esculentum), we investigated external and internal detoxification mechanisms of two self-compatible species: tartary tataricum) wild homotropicum). Both showed tolerance comparable buckwheat. Furthermore, these also secreted oxalate rapidly from roots...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure of brevetoxin A as constructed from NMR and mass spectral dataJan Pawlak, Michael S. Tempesta, Jerzy Golik, G. Zagorski, Min Lee, Koji Nakanishi, Takashi Iwashita, L. Gross, Kenneth B. TomerCite this: J. Am. Chem. Soc. 1987, 109, 4, 1144–1150Publication Date (Print):February 1, 1987Publication History Published online1 May 2002Published inissue 1 February...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPartial structures of maitotoxin, the most potent marine toxin from dinoflagellate Gambierdiscus toxicusMichio Murata, Takashi Iwashita, Akihiro Yokoyama, Masahiro Sasaki, and Takeshi YasumotoCite this: J. Am. Chem. Soc. 1992, 114, 16, 6594–6596Publication Date (Print):July 1, 1992Publication History Published online1 May 2002Published inissue 1 July...