A5115601958- High-Temperature Coating Behaviors
- Metal and Thin Film Mechanics
- Marine Biology and Environmental Chemistry
- Advanced materials and composites
- Diamond and Carbon-based Materials Research
- Bone Tissue Engineering Materials
- Polymer Surface Interaction Studies
- Ubiquitin and proteasome pathways
- Advanced Photocatalysis Techniques
- Corrosion Behavior and Inhibition
- Aluminum Alloys Composites Properties
- Electrocatalysts for Energy Conversion
- Fuel Cells and Related Materials
- Protein Structure and Dynamics
- Glycosylation and Glycoproteins Research
- Aluminum Alloy Microstructure Properties
- Gas Sensing Nanomaterials and Sensors
- Advanced ceramic materials synthesis
- Microplastics and Plastic Pollution
- Catalytic Processes in Materials Science
- Surface Modification and Superhydrophobicity
- ZnO doping and properties
- Tribology and Wear Analysis
- TiO2 Photocatalysis and Solar Cells
- Advanced Battery Technologies Research
Chinese Academy of Sciences
2016-2025
Guangdong 999 Brain Hospital
2022-2025
Wenzhou Medical University
2024-2025
Ningbo Institute of Industrial Technology
2016-2025
University of Chinese Academy of Sciences
2017-2025
Zhengzhou University
2002-2025
Theranostics (New Zealand)
2025
Institute of Plasma Physics
2022-2024
The University of Western Australia
2019-2024
Lanzhou University
2004-2024
The pathogenesis of Alzheimer's disease is characterized by the aggregation and fibrillation 40-residue A beta(1-40) 42-residue beta(1-42) peptides into amyloid plaques. structural changes associated with conversion monomeric beta peptide building blocks multimeric fibrillar beta-strand aggregates remain unknown. Recently, we established that oxidation methionine-35 side chain to sulfoxide (Met35(red) --> Met35(ox)) significantly impedes rate peptide. To explore this effect at greater...
Summary Selenite is a predominant form of selenium (Se) available to plants, especially in anaerobic soils, but the molecular mechanism selenite uptake by plants not well understood. ltn1 , rice mutant previously shown have increased phosphate (Pi) uptake, was found exhibit higher than wild‐type both concentration‐ and time‐dependent assays. Respiratory inhibitors significantly inhibited wildtype mutant, indicating that coupled with H + energy‐dependent. greatly enhanced under Pi‐starvation...
Magnesium (Mg) and its alloys have been suggested as revolutionary biodegradable materials. However, fast degradation hinders clinic application. To improve the corrosion resistance biocompatibility of Mg-Nd-Zn-Zr alloy (JDBM), magnesium-aluminum-layered double hydroxide (Mg-Al LDH) was successfully introduced into Mg(OH)2 coating by hydrothermal treatment. The anions in interlayer Mg-Al LDH can be replaced chloride ions, resulting a relatively low ion concentration near surface coating....
We present an in situ reduction method to synthesize a novel structured MnO2/mesoporous carbon (MnC) composite. MnO2 nanoparticles have been synthesized and embedded into the mesoporous wall of CMK-3 materials by redox reaction between permanganate ions carbons. Thermogravimetric analysis (TG), X-ray photoelectron spectrum (XPS), diffraction (XRD), nitrogen sorption, transmission electron microscopy (TEM), cyclic voltammetry were employed characterize these composite materials. The results...
Regardless of its successful clinical applications, load-bearing implant applications hydroxyapatite (HA) remain problematic due to intrinsic property limitations. Recent findings the promising biocompatibility graphene imply possibilities it being potentially used as additives for HA-based composites with enhanced mechanical properties. Here we report HA-reduced graphite oxide nanocomposites synthesized by a liquid precipitation approach followed spark plasma sintering consolidation. The...
Cullin-RING ubiquitin ligase (CRL), with its founding member of SKP1-Cullins-F-box proteins (SCF) E3 ligase, is the largest family ligases, which requires cullin neddylation for activation. Recently, an inhibitor NEDD8 activating enzyme (NAE), MLN4924, was reported to block and inactivate CRL/SCF E3, resulting in apoptosis induction tumor suppression both vitro vivo. We report here that not sole mechanism by MLN4924 suppresses cell growth because moderately induced drug some cancer lines...
Chemical exchange saturation transfer (CEST) provides an indirect means to detect exchangeable protons within tissues through their effects on the water signal. Previous studies have suggested that amide proton (APT) imaging, a specific form of CEST, detects endogenous with resonance frequency offset 3.5 ppm downfield from water, and thus may be sensitive variations in mobile proteins/peptides tumors. However, as CEST measurements are influenced by various confounding effects, such spillover...
We have developed a simple and green method for synthesis of blue fluorescent peptide-templated Cu nanoclusters (NCs) which display temperature dependent fluorescence low toxicity as probe sensing cellular imaging.
Mutational inactivation of the tumor suppressor tuberous sclerosis complex 2 (TSC2) constitutively activates mTORC1, increases cell proliferation, and induces pathological manifestations observed in (TS) pulmonary lymphangioleiomyomatosis (LAM). While role mTORC1 TSC2-dependent growth has been extensively characterized, little is known about mTORC2. Our data demonstrate that mTORC2 modulates TSC2-null proliferation survival through RhoA GTPase Bcl2 proteins. was inhibited not only by...
Titanium dioxide (TiO2) is a commonly used photocatalysis for the oxidation of hydrogen sulfide (H2S). However, low surface area and adsorption ability TiO2 limit photocatalytic decomposition rate. Here, tunable metal–organic framework (MOF) coating applied to hollow nanoparticles using versatile step-by-step self-assembly strategy. The structure provides high area, selected MIL-101 (Cr) MOF has regenerable H2S. TiO2@MIL-101 double-shell particles enable catalytic cycle involving...
Selenium (Se) is an essential trace element for humans and other animals, yet approximately one billion people worldwide suffer from Se deficiency. Rice a staple food over half of the world's population that major dietary source Se. In paddy soils, rice roots mainly take up selenite. speciation analysis indicated most selenite absorbed by predominantly transformed into selenomethinone (SeMet) retained in roots. However, mechanism which SeMet transported plants remains largely unknown. this...