Summary: Purpose: To determine whether refractory epilepsy affects the health‐related quality of life (HRQOL) children with or without intellectual disability (ID), and if presence ID independently compromises HRQOL in epilepsy. Methods: Subjects were parents epilepsy, whose syndrome had been defined using ILAE (International League Against Epilepsy) criteria video‐EEG monitoring. Children absence determined by formal neuropsychological educational assessment. The relative effect on two...

To determine if epilepsy surgery is effective in improving the quality of life (QOL) children with intractable seizures using Quality Life Childhood Epilepsy Questionnaire (QOLCE).The authors conducted a prospective study families 35 who underwent surgery. Parents completed QOLCE preoperatively and again 6 to 18 months after At both assessment dates parents indicated severity their child's during past frequency 4 weeks on Likert-type scales. Children were split into two groups according...

The aim of the present studies was to investigate relationship between primary and secondary control use superstitious strategies under conditions uncertainty stress. In first study, 78 participants completed a chance‐determined card‐guessing task in which they were permitted psychic's card selections instead making their own selections. Participants' strategy (a selections) increased significantly with perceived likelihood failure, regardless belief psychic ability. A second study (N = 102)...

This paper reports a study that examines how Australians are responding to the policy of multiculturalism. The aim was define different social representations policy. Multiple scalogram analysis (MSA) yielded 3 facets multiculturalism (active/passive, substantial/minimal, and threat/benefit). Using these facets, subjects were categorized into representation groups. results illustrate methodological utility using facet theory techniques representations.

Abstract A common treatment focus for work with sex offenders is the development of “victim empathy”. It asserted that by developing offenders’ empathy towards their victims, re-offending will be reduced. However, clinical and empirical evidence indicates remains a major problem among treated offenders. The present paper reports on evaluation programme designed to increase empathic ability. Overall, was very successful in improving scores measures empathy. one area did not improve ability...

Metaheuristic search algorithms look for solutions that either maximise or minimise a set of objectives, such as cost performance. However most real-world optimisation problems consist nonlinear with complex constraints and conflicting objectives.

Mass production and use of antibiotics has led to the rise resistant bacteria, a problem possibly exacerbated by inappropriate non-optimal application. Antibiotic treatment often follows fixed-dose regimens, with standard dose antibiotic administered equally spaced in time. But are such regimens optimal or can alternative be designed increase efficacy? Yet, few mathematical models have aimed identify treatments based on biological data infections inside living host. In addition, assumptions...

Objective: To assess the impact of a hospital based educational campaign on prescription and use hypnotic sedative drugs. Design: Two three-month cross-sectional surveys were performed. The first was to obtain baseline evaluation drug within hospital, second evaluate success an intervention designed promote more rational prescribing these Setting: St Vincent's Hospital, Sydney, tertiary referral hospital. Patients: Five patients randomly selected each day from hospital's admission list (only...

We propose that process algebras and evolutionary algorithms have complementary strengths for developing models of complex systems. Evolutionary are powerful methods finding solutions to optimisation problems with large search spaces but require an accurately defined fitness function provide valid results. Process effective method defining interacting processes, tuning parameters allow model outputs match experimental data can be difficult. Defining in the first place also problematic. Our...

This paper presents initial results of applying a Genetic Programming (GP) approach to the evolution process algebra models defined in Bio-PEPA. An incomplete model system is provided together with target behaviour. GP then used evolve new definitions that complete while ensuring good fit data. Our show set effective can be developed this either directly or further refined using modeller's domain knowledge. Such an greatly reduce time taken develop models, enabling modeller focus on subtler...

Sir: 'Statistical inference from experimental or observational data has become indispensable in medical research.' So said Abt [1]. We agree, and would like to comment on methods of comparing the development responses over time two groups patients. A technique known as repeated measures analysis variance, that provides a neat way expressing results, will be described. appreciate readers this journal are not statisticians, but we confident most them have sufficient contact with statistics...

This paper introduces a new hybrid Genetic Algorithm (GA) crossover approach, Targeted EDA (TEDA), that combines targeted intervention principle with Estimation of Distribution Algorithms (EDA) to solve optimal control problems. The approach is suited tasks where the number interventions used an important part solution fitness and includes problems such as cancer chemotherapy scheduling. Fitness Directed Crossover (FDC) modified GA method actively drives selected towards those fitter...

Many patients undergoing treatment for head and neck cancer (HNC) experience significant swallowing difficulties, there is some evidence that exercises may improve outcomes, including quality of life. This feasibility study developed an evidence-based, practical Swallowing Intervention Package (SiP) chemoradiotherapy (CRT) HNC. As part the study, electronic version SiP (e-SiP) was concurrently to support self-manage during treatment. paper reports on e-SiP component this work.The objective...

We conduct a study of local optima networks (LONs) in search space using fractal dimensions. The dimension (FD) these is complexity index which assigns non-integer to an object. propose fine-grained approach obtaining the FD LONs, probabilistic transitions encoded LON edge weights. then apply multi-fractal calculations LONs for first time, comparing with mono-fractal analysis. For complex systems such as dimensionality may be different between two sub-systems and analysis needed. Here we...