Holly N. Currie

ORCID: 0000-0002-0263-3413
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About
Contact & Profiles
Research Areas
  • Computational Drug Discovery Methods
  • S100 Proteins and Annexins
  • Mitochondrial Function and Pathology
  • Wound Healing and Treatments
  • Gene Regulatory Network Analysis
  • Bioinformatics and Genomic Networks
  • Pharmacological Receptor Mechanisms and Effects
  • 3D Printing in Biomedical Research
  • COVID-19 and Mental Health
  • Diabetic Foot Ulcer Assessment and Management
  • Genetics, Aging, and Longevity in Model Organisms
  • Exercise and Physiological Responses
  • Mindfulness and Compassion Interventions
  • Adipose Tissue and Metabolism
  • Tryptophan and brain disorders
  • Immune Response and Inflammation
  • Inflammatory mediators and NSAID effects
  • Ubiquitin and proteasome pathways
  • Neuroscience, Education and Cognitive Function
  • Tendon Structure and Treatment

Frostburg State University
2020

West Virginia University
2013-2017

Morgantown High School
2014

Stress and anxiety can interfere with learning, for many people, studying chemistry is perceived as a stressful endeavor. The COVID-19 pandemic has provided an additional source of stress students brought focus to the importance well-being in learning process. An improved understanding relationship between coupled experience ways mitigate such mindfulness practice benefit both instructors navigating times. This commentary provides brief overview neuroscience relation describes use remote...

10.1021/acs.jchemed.0c00777 article EN Journal of Chemical Education 2020-08-06

Modern toxicological evaluations have evolved to consider toxicity as a perturbation of biological pathways or networks. As such, testing approaches are shifting from common end point pathway based approaches, where the degree select is monitored. These new greatly increasing data available toxicologists, but methods analyses determine inter-relationships between potentially affected needed fully understand consequences exposure. An approach construct dose-response curves that use graph...

10.1021/tx400247g article EN Chemical Research in Toxicology 2013-12-22

The rapid pharmacodynamic response of cells to toxic xenobiotics is primarily coordinated by signal transduction networks, which follow a simple framework: the phosphorylation/dephosphorylation cycle mediated kinases and phosphatases. However, time course from initial response(s) cell death following exposure can have vast range. Viewing this lag between early signaling events ultimate cellular as an opportunity, we hypothesize that monitoring phosphorylation proteins related survival...

10.1093/toxsci/kfu089 article EN Toxicological Sciences 2014-05-14
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