A facile synthetic route to dimethylsila[7]helicene by using a Lewis acid catalyzed double-cyclization reaction for construction of the twisted two phenanthrene moieties is described. Sila[7]helicene exhibited high fluorescence quantum yield and realatively large g value (dissymmetric factor) circularly polarized luminencence (CPL) small molecules.

A solid-state dedicated circular dichroism (CD) spectrophotometer (J-800KCM) was designed and constructed. As a CD is polarization–modulation instrument, spectra are necessarily accompanied by artifacts due to macroscopic anisotropies such as linear birefringence (LB) (LD) which unique the solid state. photomultiplier with least polarization characteristics photoelastic modulator (PEM) residual static were selected for new based on electrical optical systems of commercially available...

Nalidixic acid, enoxacin, and other antibacterial 4-quinolones inhibit DNA gyrase activity by interrupting breakage reunion A subunits of the A2B2 complex. Despite their clinical importance, mode quinolone action mechanisms resistance are poorly understood at molecular level. Using a fragment enrichment procedure, we isolated gyrA gene from uropathogenic Escherichia coli strain that encodes protein cross-resistant to variety quinolones. When complemented with B subunit, purified...

Making up a foursome: Self-assembly of 4,4′-(3-pyridinemethoxy)benzophenone (L) and Pd(NO3)2 resulted in the quantitative formation quadruply stranded metallohelicate [Pd2(L)4], which undergoes spontaneous dimerization to an unprecedented chiral interlocked [Pd2(L)4]2 (see X-ray structure; C black, H white, N blue, O red). Supporting information for this article is available on WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z703162_s.pdf or from author. Please note: The publisher...

Although there are many examples of catenanes, those more complex mechanically interlocked molecular architectures rare. Additionally, little attention has been paid to the degradation such systems into their starting complexes, although formation and complementary phenomena equally important. Interlocked metallohelicate, [(Pd(2)L(4))(2)](8+) (2(8+)), is a quadruply architecture consisting two monomers, [Pd(2)L(4)](4+) (1(4+)). 2(8+) three internal cavities, each which encapsulates one...

ABSTRACT The establishment of left-right body asymmetry is a key biological process that tightly regulated genetically. In the first application CRISPR/Cas9 to mollusc, we show decisively actin-related diaphanous gene Lsdia1 single maternal determines shell coiling direction freshwater snail Lymnaea stagnalis. Biallelic frameshift mutations produced sinistrally coiled offspring generation after generation, in otherwise totally dextral genetic background. This sought for over century. We also...

A three-component molecular cocrystal material has been prepared by a solvent-free route involving mechanical grinding of the pure phases individual components. This is not accessible from conventional solution-state crystallization procedures. Due to fact that procedure intrinsically leads microcrystalline powder sample, use X-ray diffraction data essential for structure determination. work emphasizes scope and utility ab initio solution directly carrying out structural characterization new...

Co-grinding of crystals racemic-bis-beta-naphthol (rac-BN) and benzoquinone (BQ) produces a novel crystal adduct through sheering molecular diffusion processes in the solid state, which is structurally distinct from adducts obtained solution or melt.

Solid-state CD spectroscopy can provide valuable information on conformation, intermolecular interactions, including chirality induction, and enantioselective reactions which occur specifically in the solid state. The technique can, however, suffer from serious artifacts. Some examples of solid-state are given potential artifacts discussed. Copyright 2000 Wiley-Liss, Inc.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInteraction of bleomycin A2 with deoxyribonucleic acid: DNA unwinding and inhibition bleomycin-induced breakage by cationic thiazole amides related to A2L. Mark Fisher, Reiko Kuroda, Ted T. SakaiCite this: Biochemistry 1985, 24, 13, 3199–3207Publication Date (Print):June 18, 1985Publication History Published online1 May 2002Published inissue 18 June...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrystal and molecular structure of three isomers dichlorodiamminedihydroxoplatinum(IV): cis-trans isomerization on recrystallization from waterReiko Kuroda, Stephen Neidle, Ismail M. Ismail, Peter J. SadlerCite this: Inorg. Chem. 1983, 22, 24, 3620–3624Publication Date (Print):November 1, 1983Publication History Published online1 May 2002Published inissue 1 November...

Abstract Solid-state circular dichroism spectra of some tris(diamine) cobalt(III) complexes were measured. Each CD band region was decomposed into E and A2 components by combining the in uniaxial single-crystals microcrystalline states. The observed values R(E) R(A2) compared with theoretical calculation Mason Seal based on dynamic coupling method. agreements are generally good for those five-membered chelate rings, however, there discrepancies six- seven-membered ring cases.

Abstract The signs of solid‐state circularly polarized luminescence (CPL) axially chiral binaphthyl organic fluorophores were successfully controlled by changing the environment their matrices from a poly(methyl methacrylate) (PMMA) film‐dispersed state to KBr pellet‐dispersed state.

A vanadium(V) complex with the formula [Et3NH][VVO2(sox-pydx)] a new tridentate ligand 2-[2-[[3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl]methylene]hydrazinyl]-2-oxoacetamide (soxH-pydxH), obtained by condensation of oxamohydrazide and pyridoxal (one forms vitamin B6), has been synthesized. The compound was characterized various analytical spectroscopic methods, its structure determined single-crystal X-ray diffraction technique. Density functional theory (DFT) time-dependent DFT...

The crystal structures of three series clathrate compounds with organic guest molecules G have been determined, Cd(CN)2·G, [CdM(CN)4]·2G (M = Hg or Zn) and [NMe4·G][CuM(CN)4](M Cd Zn). cubic Fdmunit-cell parameter for the first (Z= 8) ranges from 12.647(6)Å CHCl3 to 12.767(2)Å CCl3CF3, depending on molecular size orientation in cavity. In second space group Fdm is unchanged upon 50% substitution Zn owing random distribution tetrahedral centres; lattice varies little when M Hg, but a=...

A supramolecular propeller: trinuclear EuIII helix with six chiral bipyridine-carboxylate ligands self-assembles complete diastereoselectivity (see graphic; Eu green, O red, N blue). Ground- and excited-state chiroptical properties of this red-emissive complex reflect the helical arrangement around metallic core. Supporting information for article is available on WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z500094_s.pdf or from author. Please note: The publisher not responsible...

The crystal and molecular structure of two habits [5]helicene, forms A B, have been determined their respective packing modes are compared, together with those other members the helicene series. Form crystallizes from n-pentane in space group P21/c a= 5.8150(7), b= 14.178(1), c= 17.498(1)Å, β= 94.41(1)°, Z= 4, while form B ethanol solution belongs to A2/a 26.013(2), 8.898(1), c=19.494(2)Å, 103.94(1)°, Z=12.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTertiary phosphine complexes of gold(I) and gold(III) with imido ligands: 1H, 31P, 15N NMR spectroscopy, antiinflammatory activity, x-ray crystal structure (phthalimido)(triethylphosphine)gold(I)Susan J. Berners Price, Michael DiMartino, David T. Hill, Reiko Kuroda, Muhammed A. Mazid, Peter SadlerCite this: Inorg. Chem. 1985, 24, 21, 3425–3434Publication Date (Print):October 1, 1985Publication History Published online1 May 2002Published inissue 1...

We have recently reported on dinuclear complexes Lambda,Lambda-[Co(2)L(2)Cl(2)]CoCl(4) of two novel chiral ligands (1a and 1b) which contain pyridyl-imine chelate groups (Telfer, S. G.; Sato, T.; Kuroda, R. Chem. Commun. 2003, 1064-1065). The absolute configuration the cobalt(II) centers was unambiguously assigned by X-ray crystallography. However, sign exciton couplets in their CD spectra opposite to that expected basis stereochemistry metal centers. present a rationalization these...

The pinene-bipyridine carboxylic derivatives (+)- and (-)-HL, designed to form configurationally stable lanthanide complexes, proved their effectiveness as chiral building blocks for the synthesis of lanthanide-containing superstructures. Indeed a self-assembly process takes place with complete diastereoselectivity between enantiomerically pure ligand L(-) Ln(III) ions (La, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er), thus leading quantitative formation trinuclear supramolecular architecture general...