A5042203602- Psoriasis: Treatment and Pathogenesis
- Autoimmune Bullous Skin Diseases
- Cancer and Skin Lesions
- Genetic and rare skin diseases.
- Dermatology and Skin Diseases
- Dermatological and Skeletal Disorders
- Nail Diseases and Treatments
- Nonmelanoma Skin Cancer Studies
- Cutaneous lymphoproliferative disorders research
- Cutaneous Melanoma Detection and Management
- Sarcoma Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Skin and Cellular Biology Research
- Eosinophilic Disorders and Syndromes
- Oral Health Pathology and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Autoimmune and Inflammatory Disorders
- Cancer Diagnosis and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Neurogenesis and neuroplasticity mechanisms
- Fungal Infections and Studies
- Spondyloarthritis Studies and Treatments
- Allergic Rhinitis and Sensitization
- Genital Health and Disease
- Skin Diseases and Diabetes
Central University Hospital of Asturias
2016-2025
Universidad de Oviedo
2001-2024
Instituto de Investigación Sanitaria del Principado de Asturias
2022-2024
Hospital Clínico Universitario Lozano Blesa
2015-2016
Hospital Universitario De Cabueñes
2002-2011
Hospital Universitario Ramón y Cajal
2009
Hospital de Cruces
2002
Intensive Care Society
2001
Centro de Biología Molecular Severo Ochoa
1992
Universidad Autónoma de Madrid
1992
La psoriasis ungueal afecta a un número importante de pacientes con psoriasis. No obstante, son raros los estudios epidemiológicos que recojan las características estos individuos. Describimos la epidemiología y principales ungueal. Se trata estudio prospectivo casos controles realizado en el Hospital Universitario Marqués Valdecilla Central Asturias entre enero 2007 diciembre 2009. De total 661 fue diagnosticada 47,4% pacientes. prevalencia 13,5 puntos mayor hombres mujeres. Los afectación...
Abstract Background Dupilumab, inhibiting interleukin 4 and 13, is the first monoclonal antibody licensed for atopic dermatitis (AD) since 6 months of age. Objectives The study describes patients' profile, effectiveness safety in real life dupilumab adolescents with moderate‐severe AD children severe AD. Methods National, multicentre, observational, retrospective study, based on medical records' data extracted September 2023. Patients included were (12–17 years) (Eczema Area Severity Index...
Background: Most patients with respiratory allergy are polyallergic. Combining different allergen extracts in the same allergen-specific immunotherapy is a common practice. However, it should be justified. Objective: To analyze stability, safety, and immune response of extract mixtures from nonhomologous groups. Methods: We analyzed 2 depigmented-polymerized mixture (DPmixEs): cat dander–grass pollen Alternaria alternata–grass pollen. The stability was investigated by studying proteolysis...
La psoriasis ungueal afecta a un número importante de pacientes con psoriasis. No obstante, son raros los estudios epidemiológicos que recojan las características estos individuos. Describimos la epidemiología y principales ungueal. Se trata estudio prospectivo casos controles realizado en el Hospital Universitario Marqués Valdecilla Central Asturias entre enero 2007 diciembre 2009. De total 661 fue diagnosticada 47,4% pacientes. prevalencia 13,5 puntos mayor hombres mujeres. Los afectación...
There is accumulating evidence showing a relationship between psoriasis and an increased risk of developing cardiovascular factors, including diabetes mellitus type 2 ischemic heart disease. Our aim was to investigate if there any difference in the profile among psoriatic patients based on clinical findings. To test this, we carried out prospective descriptive hospital-based study. results suggest that highest suffering from non-familial late-onset disease arthritis.
ABSTRACT Necrobiosis lipoidica (NL) is a disease of collagen. Squamous cell carcinomas developing in areas chronic ulceration and scarring have been well documented variety skin diseases but rarely necrobiosis lipoidica. The case history 76‐year‐old female presented, whose squamous carcinoma appeared 30 years after the diagnosis clinical histopathological picture described, stressing importance unusual association two pathologies prognostic.
Neural stem cells with self-renewal and multilineage potential persist in the subventricular zone of adult mammalian forebrain. These remain relatively quiescent but, under certain conditions, can be stimulated, giving rise to new neurons. Liver growth factor (LGF) is a mitogen for liver that shows biological activity extrahepatic sites useful neuroregenerative therapies. The aim this study was investigate neurogenic LGF 6-hydroxydopamine rat model Parkinson's disease. Proliferation...
An 18‐year‐old woman was referred for the evaluation of a dull gray macule on left breast. From age 13 years, patient noted breast asymmetry beginning with development and presence pigmented stain its border. Physical exploration revealed hypoplasia homogeneous, light brown side ( Fig. 1 ) without infiltration. Papules pustules were located mainly around Becker's nevus anterior chest wall. Biopsy specimens Fontana's disclosed hyperpigmented acanthotic epidermis. A diagnosis nevus, acne,...
Neural stem cells (NSCs) with self-renewal and multilineage potential are considered good candidates for cell replacement of damaged nerve tissue. Several studies have focused on the ability neurotrophic factors coadministration to improve efficiency grafted NSCs. Liver growth factor (LGF) is an hepatic mitogen that promotes regeneration tissues, including brain It has neurogenic activity partially restored nigrostriatal dopaminergic system in experimental model Parkinson's disease. Present...
The nails are affected in a substantial number of patients with psoriasis. Nevertheless, few epidemiological studies have reported the characteristics nail Here we describe epidemiology psoriasis and main patients. We undertook prospective case-control study at Hospital Universitario Marqués de Valdecilla Central Asturias Spain between January 2007 December 2009. Of total 661 included, 47.4% were diagnosed psoriasis, which was 13.5% more prevalent men. group disease had severe (12.82 vs 8.22...
Q fever is an uncommon zoonotic rickettsial disease with no exanthem or specific cutaneous lesions. Only nonspecific involvement has been reported to date. A 69‐year‐old Spanish woman chronic myelogenous leukaemia developed and two subcutaneous nodules. The patient complained of extreme pain. Biopsy revealed a granulomatous lobular panniculitis characteristic 'fibrin ring' 'doughnut' appearance: fibrin inflammatory cells arranged around central clear space. Changes membranous lipodystrophy...
Several studies suggest that patients with psoriasis have a higher incidence of neoplasms, especially the skin, which could be associated use therapies to treat psoriasis. Furthermore, evidence available on safety profile some treatments in this context, and management these is scarce, why clinical practice guidelines recommendations cancer are ambiguous. This study provides currently for patients. They result Delphi consensus reached by 45 dermatologists Spanish Academy Dermatology...