A5088902348- Malaria Research and Control
- HIV/AIDS drug development and treatment
- Research on Leishmaniasis Studies
- Computational Drug Discovery Methods
- Tuberculosis Research and Epidemiology
- Synthesis and biological activity
- ATP Synthase and ATPases Research
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Bioactive Compounds and Antitumor Agents
- Diagnosis and treatment of tuberculosis
- Cancer therapeutics and mechanisms
- RNA Interference and Gene Delivery
- Mosquito-borne diseases and control
- Mycobacterium research and diagnosis
- Antimicrobial Peptides and Activities
University of Delhi
2017-2025
Though great progress has been made to eliminate malaria globally, effective and inexpensive strategies design new antimalarials are still required due the problem of drug resistance currently used antimalarials. Herein, in continuation our efforts improve therapeutic efficacy 4-aminoquinoline-pyrimidine (4-AQ-Py) based molecular hybrids, a series 4-AQ-Py hybrids linked through diamine-piperazine (flexible rigid) linkers was synthesized assessed for vitro antiplasmodial activity. In assay,...
Abstract A persistent infection prolongs treatment duration and also enhances the chance of resistance development against antibiotics. Recently, a class amphiphilic indole derivatives was discovered exhibiting bactericidal activity both growing nongrowing Mycobacterium bovis BCG ( M. BCG). These antibacterials are suggested to disturb integrity functioning cell membrane, property that can help eradicate organisms. This study article describes field‐based three‐dimensional quantitative...