A5000554723- Sarcoma Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Cardiac tumors and thrombi
- Cardiac, Anesthesia and Surgical Outcomes
- Pelvic and Acetabular Injuries
- Colorectal and Anal Carcinomas
- Pancreatitis Pathology and Treatment
- Appendicitis Diagnosis and Management
- Colorectal Cancer Surgical Treatments
- Diverticular Disease and Complications
- Gastric Cancer Management and Outcomes
- Bone Tumor Diagnosis and Treatments
- Glycosylation and Glycoproteins Research
- Hip and Femur Fractures
- Surgical site infection prevention
- Vascular Tumors and Angiosarcomas
- Anorectal Disease Treatments and Outcomes
- Hip disorders and treatments
- Galectins and Cancer Biology
- Global Health and Surgery
- Peripheral Nerve Disorders
- Transplantation: Methods and Outcomes
- Liver Disease and Transplantation
- Esophageal and GI Pathology
- Spinal Fractures and Fixation Techniques
University of Edinburgh
2024
Université de Rennes
2019-2022
Centre Hospitalier Universitaire de Rennes
2017-2021
Institut Curie
2017-2019
Hôpital Pontchaillou
2019
CIC Rennes
2019
Inserm
2019
Université Paris Sciences et Lettres
2017-2019
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer worldwide, as result of late diagnosis and limited therapeutic options. Tumour microenvironment (or stroma) plays key role in onset progression constitutes an intrinsic histological hallmark PDAC. Thus we hypothesised that relevant prognostic biomarkers targets can be identified the stroma. Methods Laser microdissection stroma from freshly frozen PDAC was combined to gene expression profiling. Protein candidate...
Although standardization of pancreaticoduodenectomy (PD) has improved postoperative outcomes, morbidity remains high. Fast-track surgery programs appear to improve morbidity, and avoiding nasogastric tube decompression (NGTD), already outdated in most major abdominal surgery, is strongly suggested after PD by fast-track but lacks high-level evidence, especially regarding safety.To assess a randomized clinical trial whether the absence systematic NGTD reduces complications.The IPOD study...
11568 Background: Retroperitoneal sarcoma (RPS) are complex to treat. We previously reported that management and surgery in a reference center independent prognostic factors for relapse free survival (RFS) sarcoma. Here, we investigated the impact of on RFS overall (OS) nationwide NETSARC study. Methods: (netsarc.org) is network 26 centers, funded by French NCI. Since 2010, second pathological review mandatory patients (pts) facilitating exhaustive collection. Pts characteristics follow-up...
Background: Identifying the gluteal vessels during a posterior sacrectomy can be challenging. This study defines anatomical landmarks that used to approximate location of superior and inferior arteries (SGA IGA) sacrectomy. Methods: Cadaveric dissection six fresh adult pelvises determine SGA IGA in relation posterior-inferior aspect sacroiliac joint (PISIJ), lateral sacral margin sacrococcygeal (SCJ). Results: The are easily palpable. position PISIJ is relatively constant as it tethered by...
Monobloc resection of soft tissue sarcomas (STSs) has a major impact on overall survival and local recurrence. Anatomical boundaries, such as the sciatic notch, increase risk fragmentation lesion. To date there are few papers describing optimal surgical technique to remove STSs. The objective this study is describe simultaneous anterior posterior approach for notch dumbbell tumours. We present management two patients diagnosed with well-differentiated liposarcomas retroperitoneal gluteal...
Few studies have analyzed outcomes of liver transplantation (LT) when the recipient hepatic artery (HA) was not usable.We retrospectively evaluated LT performed using different alternative sites to HA.Between 2002 and 2017, 1,677 were in our institution among which 141 (8.4%) with unusable HA analyzed. Four groups defined according site anastomosis: splenic (SA group, n=26), coeliac trunk (CT n=12), aorta or donor's vessel (Ao n=91) a vascular prosthesis (Ao-P n=12) as conduit. The median...
Background Anastomotic leakage following colorectal surgery remains a frequent complication. We report rare case of fatal epidural abscess caused by colo-epidural fistula complicating laparoscopic proctectomy.Case presentation A 62 year-old-man presented with weight loss, pelvic sepsis and neurological dysfunction four months after closing the ileostomy proctectomy for rectal adenocarcinoma one year ago. Cross-sectional imaging confirmed an chronic anastomotic leak. Systemic antibiotics...
Bacteriobilia may increase the rate of deep infectious complications (DIC) after pancreaticoduodenectomy. To better adjust prophylactic and empirical antibacterial treatment, we aimed to characterize bacteriobilia in patients with preoperative endoprosthesis, its association postoperative DIC.All who underwent pancreaticoduodenectomy our center between 2010 2019 were included. The microbiological findings from bile samples, DIC was analyzed, compared microbiology data 2010-2014 2015-2019...