- Orthopedic Surgery and Rehabilitation
- Nerve Injury and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Peripheral Nerve Disorders
- Nerve injury and regeneration
- Shoulder Injury and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Tendon Structure and Treatment
- Bone fractures and treatments
- Shoulder and Clavicle Injuries
- Orthopaedic implants and arthroplasty
- Musculoskeletal synovial abnormalities and treatments
- Dupuytren's Contracture and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Hip and Femur Fractures
- Neurogenesis and neuroplasticity mechanisms
- Musculoskeletal Disorders and Rehabilitation
- Congenital limb and hand anomalies
- Stochastic Gradient Optimization Techniques
- Plant-based Medicinal Research
- Surgical site infection prevention
- Traumatic Brain Injury Research
- Titanium Alloys Microstructure and Properties
- Reliability and Agreement in Measurement
- Pregnancy-related medical research
Allegheny General Hospital
2015-2024
Allegheny Health Network
2013-2024
Meta (United States)
2021
Menlo School
2021
Icahn School of Medicine at Mount Sinai
2020
Columbia University Irving Medical Center
2009-2019
Texas Health Dallas
2019
AxoGen (United States)
2018
Globus Medical (United States)
2018
Drexel University
2017
Acellular nerve allograft is a new option for bridging defects that allows appropriate diameter matching. The aim of the study was to compare histologic and functional recovery treated with acellular versus cabled sural autograft.Fifty-four Sprague-Dawley rats were divided into one three experimental groups. A unilateral 10 mm sciatic defect created repaired an (Group A), autografts in antidromic orientation B), newly segmental (reversed autograft) C). Two each group we evaluated...
Study Design. Cross-sectional database study. Objective. The objective of this study was to develop an algorithm for the automated measurement spinopelvic parameters on lateral lumbar radiographs with comparable accuracy surgeons. Summary Background Data. Sagittal alignment measurements are important evaluation spinal disorders. Manual methods time-consuming and subject rater-dependent error. Thus, a need exists obtaining sagittal measurements. Previous studies have been limited in accuracy,...
In this paper, we consider hybrid parallelism---a paradigm that employs both Data Parallelism (DP) and Model (MP)---to scale distributed training of large recommendation models. We propose a compression framework called Dynamic Communication Thresholding (DCT) for communication-efficient training. DCT filters the entities to be communicated across network through simple hard-thresholding function, allowing only most relevant information pass through. For communication efficient DP,...
Hemangioma is one of the most common soft tissue tumors comprising 7% all benign tumors. The etiology unclear. Many treatment modalities for symptomatic deep subdermal or intramuscular hemangioma have been used, but surgical excision preferred treatment. During past 20 years, 89 patients with hemangiomas were treated by at authors' institution. This study was done to define clinical characteristics pathologically proven and evaluate outcome operative procedures. Intralesional marginal yields...
The purpose of this study was to determine if axonal sprouting across an end-to-side coaptation could be stimulated and so, identify the source regenerating axons. Mechanical trauma, method used stimulate sprouting, compared a control group with only additional non-grafted group. After 20-week recovery period, electrical stimulation revealed that target muscles had been reinnervated in all groups except Axonal counting demonstrated significant increase for mechanical trauma [ratio density...
An ideal peripheral nerve repair construct does not currently exist. Our primary goal was to determine whether fibrin glue adds the tensile strength of conduit-assisted digital repairs. secondary evaluate impact varying suture number and location on strength.Ninety cadaveric nerves were harvested divided equally into following groups: A (4/4), B (2/2), C (0/2), D (0/1), E (0/0) with first referring sutures at coaptation second each proximal distal end nerve-conduit junction. When added,...
The interface between bone tissue and metal implants undergoes various types of mechanical loading, such as strain, compression, fluid pressure, shear stress, from daily activities. Such perturbations create suboptimal environments at the host bone-implant junction, causing an accumulation wear particles debilitating osseous integration, potentially leading to implant failure. While many studies have focused on effect macrophages or osteoprogenitor cells, differential combined effects cell...
Background: Nerve injuries with a gap/defect represent clinical challenge without clear solution. Reconstruction cable autografts is common treatment technique, and repair decellular nerve allograft newer option. The purpose of this study was to compare the functional outcomes reconstruction those matched-diameter allografts evaluate relative importance diameter as well autograft-versus-allograft nature reconstruction. Methods: A unilateral 10-mm sciatic defect created in 81 genetically...
Adipose tissue‐derived stem cells and insulin‐like growth factor‐1 (IGF‐1) have shown potential to enhance peripheral nerve regeneration. The purpose of this study was investigate the effect an in vivo biologic scaffold, consisting white adipose tissue flap (WATF) and/or IGF‐1 on regeneration a crush injury model. Forty rats all underwent sciatic then received: pedicled WATF, controlled local release IGF‐1, both treatments, or no treatment at site. Outcomes were normalized maximum isometric...
Individual fracture patterns demand specific and adequate fixation. Locked volar plating has become popular in the operative fixation of distal radius fractures. However, cases which there is a radial styloid fragment or severe comminution, amount from alone can be inadequate may lead to loss reduction. The use locked column plates Kirschner (K) wires provides additional allows surgeon tailor individual pattern. Outlined here technique combining with K-wire fixation, as well step-by-step...
In situ ulnar nerve release has been gaining popularity as a simple, effective, and low-morbidity procedure for the treatment of cubital tunnel syndrome. One concern with technique is how to manage unstable after release. It unclear much subluxation will lead problems surprisingly there no grading system assess instability. I propose such system, well new stabilize nerve. The blocking flap consists raising rectangular off flexor/pronator fascia attaching it posterior subcutaneous so that...
Multiple treatment options are available for patients who have peripheral nerve injuries with a gap. Decellular allografts one option and provide an extracellular scaffold neuronal cells to migrate axonal regrowth. Immunosuppression is not needed because improved processing technologies rendered decellular nonimmunogenic. These also shown promising results in both animal human studies as alternative repair option.