A5043468714- Silk-based biomaterials and applications
- Advanced Fiber Laser Technologies
- Photonic Crystal and Fiber Optics
- Advanced Sensor and Energy Harvesting Materials
- Laser-Matter Interactions and Applications
- Optical Network Technologies
- Electrospun Nanofibers in Biomedical Applications
- Nanofabrication and Lithography Techniques
- Biochemical and Structural Characterization
- Photonic Crystals and Applications
- Advanced Fiber Optic Sensors
- Advanced Materials and Mechanics
- Photonic and Optical Devices
- Antimicrobial Peptides and Activities
- Neurobiology and Insect Physiology Research
- Polymer Surface Interaction Studies
- 3D Printing in Biomedical Research
- Polydiacetylene-based materials and applications
- Neuroscience and Neural Engineering
- Conducting polymers and applications
- Plasmonic and Surface Plasmon Research
- Nonlinear Optical Materials Studies
- Advanced biosensing and bioanalysis techniques
- Phytochemical compounds biological activities
- Diatoms and Algae Research
Tufts University
2016-2025
Medford Radiology Group
2008-2018
Indian Institute of Technology Kharagpur
2017
University of Connecticut
2016
University of Washington
2013
University of Illinois Urbana-Champaign
1997-2012
Rogers (United States)
2012
Boston University
2008-2010
Cornell University
2010
Soochow University
2009
We report classes of electronic systems that achieve thicknesses, effective elastic moduli, bending stiffnesses, and areal mass densities matched to the epidermis. Unlike traditional wafer-based technologies, laminating such devices onto skin leads conformal contact adequate adhesion based on van der Waals interactions alone, in a manner is mechanically invisible user. describe incorporating electrophysiological, temperature, strain sensors, as well transistors, light-emitting diodes,...
Reversible Implants Silicon electronics are generally designed to be stable and robust—it would counterproductive if the key parts of your computer or cell phone slowly dissolved away while you were using it. In order develop transient for use as medical implants, Hwang et al. (p. 1640 , see cover) produced a complete set tools materials that needed make standard devices. Devices have specific lifetime, after which component materials, such porous silicon silk, resorbed by body.
Successful integration of advanced semiconductor devices with biological systems will accelerate basic scientific discoveries and their translation into clinical technologies. In neuroscience generally, in optogenetics particular, the ability to insert light sources, detectors, sensors, other components precise locations deep brain yields versatile important capabilities. Here, we introduce an injectable class cellular-scale optoelectronics that offers such features, examples unmatched...
Infrared absorption spectroscopy enabling direct access to vibrational fingerprints of the molecular structure is a powerful method for functional studies bio-molecules. Although intrinsic cross-sections IR active modes proteins are nearly 10 orders magnitude larger than corresponding Raman cross-sections, they still small compared that fluorescence-label based methods. Here, we developed new tool on collective excitation plasmonic nanoantenna arrays and demonstrated detection signatures...
We report broad bandwidth, mid-IR supercontinuum generation using a sub-cm (8 mm) length of highly nonlinear tellurite microstructured photonic crystal fiber (PCF). pump the at telecommunication wavelengths by 1550 nm, 100 fs pulses energy E=1.9 nJ. When coupled in PCF, these result (SC) bandwidth 4080 nm extending from 789 to 4870 measured 20 dBm below peak spectral power. This is comparable or excess previously reported spectra for other glass formulations despite significantly shorter...
The combined use of ZnO, Mg, MgO, and silk provides routes to classes thin-film transistors mechanical energy harvesters that are soluble in water biofluids. Experimental theoretical studies the operational aspects dissolution properties this type transient electronics technology illustrate its various capabilities. Application opportunities range from resorbable biomedical implants, environmentally dissolvable sensors, degradable consumer electronics.
An array of passive metamaterial antennas fabricated on all protein-based silk substrates were conformally transferred and adhered to the surface an apple. This process allows opportunity for intimate contact micro- nanostructures that can probe, accordingly monitor changes in, their surrounding environment. provides in situ monitoring food quality. It is be noted this type sensor consists edible biodegradable components, holding utility potential relevance healthcare food/consumer products...
Elastomeric, fully degradable, and biocompatible biomaterials are rare, with current options presenting significant limitations in terms of ease functionalization tunable mechanical degradation properties. A new method for covalently crosslinking tyrosine residues silk proteins, via horseradish peroxidase hydrogen peroxide, to generate highly elastic hydrogels properties, is reported. These materials offer gelation kinetics, swelling In addition, these polymers withstand shear strains on the...
Biocompatible silk optical waveguides are fabricated by direct-write assembly and demonstrated to guide light in both straight curved architectures. These can easily be doped or functionalized with bioactive molecules, promising materials for biophotonic devices.
Abstract Silk fibroin has been successfully used as a biomaterial for tissue regeneration. To prepare silk biomaterials human implantation series of processing steps are required to purify the protein. Degumming remove inflammatory sericin is crucial step related biocompatibility and variability in material. Detailed characterization degumming reported. The conditions significantly affected cell viability on material ability form three‐dimensional porous scaffolds from fibroin, but did not...
Significance We present the demonstration of in vivo operation a subcutaneously implanted, resorbable electronic device. The remotely controlled device was wirelessly activated after implantation, successfully eliminating infection, and subsequently dissolving surrounding tissue. This approach is first step for development class implantable, technological, biomedical devices that resorb harmlessly, need retrieval use.
Silk-based biomaterial systems have been previously explored for a variety of medical and nonmedical materials needs. The unique biophysical features silks provide options to generate highly tailored structures morphologies with this family fibrous proteins. To exploit these features, we optimized the all aqueous processing silk fibroin into novel surface nanopatterned protein materials. We exploited control nanomorphology optimize optical systems. demonstrate morphology down 125 nm,...
Protein-based composite biomaterials have been actively pursued as they can encompass a range of physical properties to accommodate broader spectrum functional requirements, such elasticity support diverse tissues. By optimizing molecular interfaces between structural proteins, useful materials be fabricated films, gels, particles, and fibers, well for electrical optical devices. Such systems provide analogies more traditional synthetic polymers yet with expanded utility due the material's...
Significance A modular 3D brain-like cortical tissue is constructed with silk protein-based scaffold and ECM composite primary neurons. This responds in vitro biochemical electrophysiological outcomes, mimicking observations of brain homeostasis mechanical injury responses.