A5083170692- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- Bioinformatics and Genomic Networks
- Monoclonal and Polyclonal Antibodies Research
- Cell Adhesion Molecules Research
- Protease and Inhibitor Mechanisms
- vaccines and immunoinformatics approaches
- ATP Synthase and ATPases Research
- Immunotherapy and Immune Responses
- Genetic Neurodegenerative Diseases
- Mitochondrial Function and Pathology
- TGF-β signaling in diseases
National University of Sciences and Technology
2022-2024
Bone morphogenetic protein 10 (BMP-10) is crucial for endothelial cell signaling via activin receptor-like kinase 1 (ALK1), a pathway central to vascular homeostasis and angiogenesis. Dysregulated BMP-10 contributes cardiovascular diseases cancer, highlighting the need control ALK1-mediated responses therapeutic development. biosynthesis involves processing by proprotein convertases (PPCs) resulting in non-covalently associated prodomain-growth factor (PD-GF) complex (CPLX), similar other...
The goal of this study was to understand the possible core genes associated with hepatocellular carcinoma (HCC) pathogenesis and prognosis.GEO contains datasets gene expression, miRNA, methylation patterns diseased healthy/control patients. GSE62232 dataset selected by employing server Gene Expression Omnibus. A total 91 samples were collected, including 81 HCC 10 healthy as control. analysed through GEO2R, Functional Enrichment Analysis performed extract rational information from a set...
Abstract Calcium (Ca 2+ ) has been observed as the most important ion involved in a series of cellular processes and its homeostasis is critical for normal functions. Mitochondrial calcium uniporter (MCU) complex recognized calcium‐specific channel located inner mitochondrial membrane one major players maintaining Ca by transporting across membrane. Furthermore, dysregulation orchestrated to neurodegenerative response. This necessitates quantitative evaluation MCU‐dependent mROS production...
Abstract The goal of this study was to understand possible core genes associated with hepatocellular carcinoma (HCC) pathogenesis and prognosis. Gene Expression Omnibus ( GEO) contains datasets gene expression, miRNA methylation patterns diseased healthy/control patients. GSE62232 Dataset selected by employing the server GEO. A total 91 samples were collected, including 81 HCC 10 healthy as control. analyzed through GEO2R, functional enrichment analysis performed extract rational information...
Abstract The goal of this study was to understand possible core genes associated with hepatocellular carcinoma (HCC) pathogenesis and prognosis. Gene Expression Omnibus ( GEO) contains datasets gene expression, miRNA methylation patterns diseased healthy/control patients. GSE62232 Dataset selected by employing the server GEO. A total 91 samples were collected, including 81 HCC 10 healthy as control. analyzed through GEO2R, functional enrichment analysis performed extract rational information...
Abstract Objective The goal of this study was to understand possible core genes associated with hepatocellular carcinoma (HCC) pathogenesis and prognosis. Methods GEO contains datasets gene expression, miRNA methylation patterns diseased healthy/control patients. GSE62232 Dataset selected by employing the server Gene Expression Omnibus. A total 91 samples were collected, including 81 HCC 10 healthy as control. analyzed through GEO2R, Functional Enrichment Analysis performed extract rational...