A5006941504- Oral microbiology and periodontitis research
- Endodontics and Root Canal Treatments
- Dental Radiography and Imaging
- 3D Printing in Biomedical Research
- Peptidase Inhibition and Analysis
- Streptococcal Infections and Treatments
- Sinusitis and nasal conditions
- Periodontal Regeneration and Treatments
- Cellular Mechanics and Interactions
- Microfluidic and Bio-sensing Technologies
- Wound Healing and Treatments
- Legionella and Acanthamoeba research
- Silk-based biomaterials and applications
Capital Medical University
2015-2022
Shanghai Stomatological Hospital
2015
Microorganisms in the complex root canal system and extraradicular regions, including periapical lesions biofilm may cause treatment failures. However, few studies described difference between intraradicular infections from same tooth associated with persistent apical periodontitis. This study aimed to characterize microbiome present canal, biofilm, The microbial communities were investigated by Illumina high-throughput sequencing using Hiseq 2500 platform. dominant phyla periodontitis...
This study explored the effects of a silk fibroin-RGD-stem cell factor (SF-RGD-SCF) scaffold on migration, proliferation, and attachment stem cells apical papilla (SCAPs). SF, SF-RGD, SF-SCF, SF-RGD-SCF scaffolds were prepared, laser confocal microscopy was used to observe adhesion growth status SCAPs scaffolds. Furthermore, numbers counted by digestion counting method evaluate their proliferation. Cells proliferated more than those other showed obvious tendency migrate scaffold’s deep...
Summary Porphyromonas gingivalis (P. gingivalis) is a major etiological agent in the development and progression of chronic periodontitis. It produces cysteine proteases (gingipains), including lysine‐specific gingipain two arginine‐specific gingipains. Heme binding uptake are fundamental to growth virulence P. . The recombinant hemagglutinin 2 domain ( rHA 2) binds hemin with high affinity. aim present work was identify key residues involved its hemin‐binding activity. A functional...
The mechanical properties of cells are great significance to their normal physiological activities. current methods used for the measurement a cell’s have problems complicated operation, low throughput, and limited measuring range. Based on micropipette technology, we designed double-layer micro-valve-controlled microfluidic chip with series arrays. has adjustment pressure ranges 0.03–1 0.3–10 kPa stabilization design, which can achieve robust single cell's under wide range is simple...