- Microfluidic and Bio-sensing Technologies
- Thermal Radiation and Cooling Technologies
- Advanced Thermoelectric Materials and Devices
- Cellular Mechanics and Interactions
- Ergonomics and Musculoskeletal Disorders
- Microfluidic and Capillary Electrophoresis Applications
- Cancer Research and Treatments
- Thermal properties of materials
- Epigenetics and DNA Methylation
- stochastic dynamics and bifurcation
- Immune Cell Function and Interaction
- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
- 3D Printing in Biomedical Research
- Diffusion and Search Dynamics
- Innovative Energy Harvesting Technologies
- Pharmacogenetics and Drug Metabolism
- CAR-T cell therapy research
- Drug Transport and Resistance Mechanisms
- Immunotherapy and Immune Responses
- Cancer, Hypoxia, and Metabolism
- Lipid Membrane Structure and Behavior
- Micro and Nano Robotics
- Endoplasmic Reticulum Stress and Disease
- CRISPR and Genetic Engineering
Peking University
2022-2025
Wenzhou University
2024
Tianjin University
2010
Abstract Colorectal cancer (CRC) continues to be a prevalent malignancy, posing significant risk human health. The involvement of alpha/beta hydrolase domain 6 (ABHD6), serine family member, in CRC development was suggested by our analysis clinical data. However, the role ABHD6 remains unclear. This study seeks elucidate relevance, biological function, and potential molecular mechanisms CRC. We investigated settings, conducting proliferation, migration, cell cycle assays. To determine...
Despite breakthroughs in treatment, ovarian cancer (OC) remains one of the most lethal gynecological malignancies, with an increasing age-standardized mortality rate. This underscores urgent need for novel biomarkers and therapeutic targets. Although growth factor receptor-bound protein 7 (GRB7) is implicated cell signaling tumorigenesis, its expression pattern clinical implications OC remain poorly characterized.
A coarse-grained model of bacterial cytoplasm is proposed to explain the size-dependent diffusion enhancement observed in bacteria. It found that an active force 0.57 pN with random orientation can quantitatively reproduce experimental data.
The mechanical properties of cells are great significance to their normal physiological activities. current methods used for the measurement a cell’s have problems complicated operation, low throughput, and limited measuring range. Based on micropipette technology, we designed double-layer micro-valve-controlled microfluidic chip with series arrays. has adjustment pressure ranges 0.03–1 0.3–10 kPa stabilization design, which can achieve robust single cell's under wide range is simple...
A new micro-thermoelectric power generator module with high packing density of film thermoelectric legs has been proposed, in which a large number p-type and n-type thin-film are electrically connected series. theoretical model established to simulate the output voltage proposed module, results shows that much higher can be obtained simply by integrating more components. Based on containing 160 thermocouples is fabricated size 25mm (length) × 4mm (width) 1mm (thickness). Its open-circuit...
Experiments have found that diffusion in metabolically active cells is much faster than dormant cells, especially for large particles. However, the mechanism of this size-dependent enhancement living still unclear. In work, we approximate net effect metabolic processes as a white-noise force and simulate model system bacterial cytoplasm with highly polydisperse particle size distribution. We find relative to can be more substantial Our simulations agree quantitatively experimental data...