- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Tuberculosis
- Pharmaceutical studies and practices
- Antibiotics Pharmacokinetics and Efficacy
- Pharmacological Effects and Toxicity Studies
- Mycobacterium research and diagnosis
- Computational Drug Discovery Methods
- Biotechnology and Related Fields
- COVID-19 Clinical Research Studies
- Science and Education Research
- HIV/AIDS drug development and treatment
Centro Universitário de Araraquara
2016-2020
No large study has ever evaluated the efficacy, safety and tolerability of meropenem/clavulanate to treat multidrug- extensively drug-resistant tuberculosis (MDR- XDR-TB). The aim this observational was evaluate therapeutic contribution, effectiveness, profile added a background regimen when treating MDR- XDR-TB cases. Patients treated with meropenem/clavulanate-containing (n=96) showed greater drug resistance than those exposed meropenem/clavulanate-sparing (n=168): in former group more...
No large study to date has ever evaluated the effectiveness, safety and tolerability of imipenem/clavulanate versus meropenem/clavulanate treat multidrug- extensively drug-resistant tuberculosis (MDR- XDR-TB). The aim this observational was compare therapeutic contribution added background regimens MDR- XDR-TB cases. 84 patients treated with imipenem/clavulanate-containing showed a similar median number antibiotic resistances (8 8) but more fluoroquinolone resistance (79.0% 48.9%,...
A tuberculose (TB) é uma doença infectocontagiosa causada pela micobactéria do gênero Mycobacterium, sendo a espécie Mycobacterium tuberculosis (Mtb) mais comum. TB afeta principalmente os pulmões, mas pode afetar praticamente todos órgãos corpo. É das doenças que causa mortes no mundo, letal por um único agente infeccioso e acomete 1/3 da população mundial. Cerca de 10 milhões pessoas desenvolvem mundo todo dois morrem anualmente. Os objetivos deste trabalho são apresentar o histórico...
Evidence on effectiveness, safety, and tolerability of imipenem/clavulanate (IC) linezolid containing regimens to treat multidrug-resistant (MDR-) extensively drug-resistant tuberculosis (XDR-TB) is scarce. The aim this observational study evaluate the therapeutic contribution IC manage MDR/XDR-TB cases at reference centre São Paulo state, Brazil. Twelve patients (9 males, 1 HIV positive in antiretroviral treatment, 4 MDR, 8 XDR) were treated with IC, 11 them within linezolid-containing...
Introdução: A tuberculose (TB) afeta 1/3 da população mundial e cerca de 10 milhões pessoas desenvolvem TB a cada ano, resultando em mais dois mortes. Objetivos: O principal objetivo deste trabalho é apresentar um estudo do perfil epidemiológico Araraquara (SP) comparar o com os padrões doença no mundo, Américas, Brasil Estado São Paulo. Método: As pesquisas informações foram coletadas relatório anual Organização Mundial Saúde (OMS), Ministério Brasil, Secretaria Paulo, Municipal Serviço...