A5107961054- Milk Quality and Mastitis in Dairy Cows
- Oral Health Pathology and Treatment
- Tuberculosis Research and Epidemiology
- Probiotics and Fermented Foods
- Mycobacterium research and diagnosis
- Cystic Fibrosis Research Advances
- Animal Genetics and Reproduction
- Neonatal Respiratory Health Research
- Microbial infections and disease research
- Tracheal and airway disorders
- Autoimmune Bullous Skin Diseases
- Nail Diseases and Treatments
- Oral and gingival health research
- Oral and Maxillofacial Pathology
- Infectious Diseases and Tuberculosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Cancer and Skin Lesions
- Veterinary medicine and infectious diseases
- Genetic factors in colorectal cancer
- Infant Nutrition and Health
- Animal Diversity and Health Studies
- Retinal and Optic Conditions
- Genetic and rare skin diseases.
- Autoimmune and Inflammatory Disorders
Istituto Zooprofilattico Sperimentale della Sardegna
2013-2024
University of Sassari
2007-2024
École de Technologie Supérieure
2004-2008
Bronchiectasis is a heterogeneous disease. This study aimed at identifying discrete groups of patients with different clinical and biological characteristics long-term outcomes. was secondary analysis five European databases prospectively enrolled adult outpatients bronchiectasis. Principal component cluster analyses were performed using demographics, comorbidities, clinical, radiological, functional microbiological variables collected during the stable state. Exacerbations, hospitalisations...
Latent infection with Mycobacterium tuberculosis is defined by a positive IFN-γ release assay (IGRA) result in the absence of active tuberculosis. Only few, mostly monocentric studies have evaluated role IGRAs to predict development recent contacts low-incidence countries tuberculosis.To analyze IGRA results and effect preventive chemotherapy on progression rates among contacts.Results from contact investigations at 26 centers 10 European including testing for latent M. QuantiFERON-TB Gold...
No large study has ever evaluated the efficacy, safety and tolerability of meropenem/clavulanate to treat multidrug- extensively drug-resistant tuberculosis (MDR- XDR-TB). The aim this observational was evaluate therapeutic contribution, effectiveness, profile added a background regimen when treating MDR- XDR-TB cases. Patients treated with meropenem/clavulanate-containing (n=96) showed greater drug resistance than those exposed meropenem/clavulanate-sparing (n=168): in former group more...
No large study to date has ever evaluated the effectiveness, safety and tolerability of imipenem/clavulanate versus meropenem/clavulanate treat multidrug- extensively drug-resistant tuberculosis (MDR- XDR-TB). The aim this observational was compare therapeutic contribution added background regimens MDR- XDR-TB cases. 84 patients treated with imipenem/clavulanate-containing showed a similar median number antibiotic resistances (8 8) but more fluoroquinolone resistance (79.0% 48.9%,...
Mastitis is the most important disease of dairy small ruminants affecting animal welfare, agricultural economy, and food safety. Only a few investigations on bacterial epidemiology udder infections have been performed. Aim study was to describe Italian mastitis in ruminant herds. An ad hoc electronic data collection module created by National Reference Center for Sheep Goat (C.Re.N.M.O.C). Public health veterinary laboratories Experimental Zooprophylactic Institutes (EE.ZZ.II) (n = 10) were...
The characterization of urinary metabolome, which provides a fingerprint for each individual, is an important step to reach personalized medicine. It influenced by exogenous and endogenous factors; among them, we investigated sex influences on 72 organic acids measured through GC-MS analysis in the urine 291 children (152 males; 139 females) aging 1-36 months stratified four groups age. Among metabolites, all age groups, 4-hydroxy-butirate homogentisate are found only males, whereas...
To evaluate the efficacy and safety of a single intravitreal dexamethasone implant (DXI) combined with antivascular endothelial growth factor (anti-VEGF) therapy, in patients neovascular age-related macular degeneration (wet-AMD) resistant to conventional treatment. In this randomized, controlled pilot study, 16 eyes 15 patients, unresponsive anti-VEGF were enrolled randomly assigned two groups: DXI + (treatment group: 11 eyes) monthly alone (control 5 eyes). Patients treated at baseline...
Alternatives to antibiotic therapy for mastitis in ruminants are needed. We present an evaluation, two trials, of the efficacy intramammary infusion a live culture Lactococcus lactis treatment subclinical and clinical ewes.In total, 67 animals were enrolled: 19 lactating ewes (study 1), including healthy (N=6) coagulase-negative staphylococci (CNS)-infected (N=13); 48 2) with either CNS (N=32), or Staphylococcus aureus (N=16), total 123 mammary glands. Intramammary infusions performed L. PBS...
ORF virus (ORFV) causes contagious ecthyma (“ORF”), a disease of sheep and goats characterized by lesions ranging from vesicles pustules to atypical papilloma-like angiomatous in the skin mucosae. The authors investigated molecular factors leading ORF-associated tumor-like changes. Fifteen lambs, 15 kids, an adult ram clinically affected natural ORFV infection were enrolled study examined several methods. was detected viral culture or real-time polymerase chain reaction (RT-PCR) lesioned...