Martin Kolditz
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Pulmonary Hypertension Research and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Emergency and Acute Care Studies
- Respiratory and Cough-Related Research
- Long-Term Effects of COVID-19
- Tuberculosis Research and Epidemiology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- SARS-CoV-2 and COVID-19 Research
- Liver Disease and Transplantation
- COVID-19 and healthcare impacts
- Actinomycetales infections and treatment
- Pleural and Pulmonary Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pediatric health and respiratory diseases
- Bacterial Infections and Vaccines
- Transplantation: Methods and Outcomes
- Cardiovascular Function and Risk Factors
- Antibiotic Use and Resistance
- Organ Transplantation Techniques and Outcomes
University Hospital Carl Gustav Carus
2016-2025
TU Dresden
2016-2025
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2016-2025
University Hospital Olomouc
2024
Carl-Thiem-Klinikum Cottbus
2024
German Center for Lung Research
2022-2024
Palacký University Olomouc
2024
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2021-2024
BioTechMed-Graz
2024
Medical University of Graz
2024
The present guideline provides a new and updated concept of treatment prevention adult patients with community-acquired pneumonia. It replaces the previous dating from 2009.The was worked out agreed on following standards methodology S3-guideline. This includes systematic literature search grading, structured discussion recommendations supported by as well declaration assessment potential conflicts interests.The has focus specific clinical circumstances, an update severity assessment, for...
The correct management of immunocompromised patients with pneumonia is debated. We evaluated the prevalence, risk factors, and characteristics coming from community pneumonia.We conducted a secondary analysis an international, multicenter study enrolling adult hospitalized in 222 hospitals 54 countries worldwide. Risk factors for immunocompromise included AIDS, aplastic anemia, asplenia, hematological cancer, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic...
Inhalt 1. Struktur der Leitlinie e6 1.1.Vorwort e61.2. Ziele Leitliniee6 1.3. Erstellung Leitliniee71.3.1. Literaturrecherchee71.3.2. Formulierung Empfehlungene71.4. Finanzierunge81.5. Implementierung/Publikatione81.6. Planmäßige Überarbeitunge81.7. Prozessqualität e8 2. Definitionen 3. Epidemiologie und sozialmedizinische Bedeutung e9 4. Erregerspektrum 5. Resistenzsituation e10 5.1. bei Streptococcus pneumoniae e105.1.1. Resistenz gegenüber Penicillin G e105.1.2. Makroliden e105.1.3....
Zusammenfassung Die vorliegende Leitlinie umfasst ein aktualisiertes Konzept der Behandlung und Prävention von erwachsenen Patienten mit ambulant erworbener Pneumonie löst die bisherige aus dem Jahre 2016 ab. Sie wurde entsprechend den Maßgaben zur Methodologie einer S3-Leitlinie erarbeitet verabschiedet. Hierzu gehören eine systematische Literaturrecherche -bewertung, strukturierte Diskussion Literatur begründbaren Empfehlungen sowie Offenlegung Bewertung möglicher Interessenskonflikte....
<h3>Background</h3> Early organ dysfunction determines the prognosis of community-acquired pneumonia (CAP), and recognition CAP as a medical emergency has been advocated. <h3>Objective</h3> To characterise patients with 'emergency CAP' evaluate predictors for very early failure or death. <h3>Methods</h3> 3427 prospectively enrolled CAPNETZ cohort were included. Emergency was defined requirement mechanical ventilation vasopressor support (MV/VS) death within 72 h 7 days after hospital...
Zusammenfassung Die nosokomiale Pneumonie bleibt eine häufige Komplikation von Krankenhausaufenthalten. meisten Daten liegen zur beatmungsassoziierten vor, aber auch auf Normalstationen ist vermehrt mit dieser Erkrankung zu rechnen. Problematisch die Zunahme Infektionen multiresistenten Erregern (MRE). Diese erschwert adäquate Initialtherapie und kann unkritischem Einsatz Breitspektrumantibiotika führen. Das vorliegende Update der S3-Leitlinie 2012 wurde einer interdisziplinären...
Background: The clinical spectrum of community-acquired pneumonia ranges from infections that can be treated on an outpatient basis, with 1% mortality, to those present as medical emergencies, a mortality above 40%.Methods: This article is based pertinent publications and current guidelines retrieved by selective search the literature.Results: radiological demonstration infiltrate required for differentiation acute bronchitis regardless whether patient seen in setting or emergency room.For...
IL-22 plays a critical role in defending against mucosal infections, but how production is regulated incompletely understood. Here, we show that mice lacking IL-33 or its receptor ST2 (IL-1RL1) were more resistant to Streptococcus pneumoniae lung infection than wild-type animals and single-nucleotide polymorphisms IL33 IL1RL1 associated with pneumococcal pneumonia humans. The effect of on S. was mediated by negative regulation innate lymphoid cells (ILCs) independent ILC2s as well IL-4 IL-13...
Community-acquired pneumonia (CAP) is a major global cause of death and hospitalization. Bacteria or community-acquired viruses (CARVs) CAP. COVID-19 associated restrictions effectively reduced the circulation CARVs. The aim this study was to analyze proportion CARVs in adult patients with CAP from mid-2020 mid-2023. Specifically, we aimed compare rate influenza virus, SARS-CoV-2, RSV detections aged 18–59 years ≥60 years. We 21 respiratory three atypical bacteria (Bordetella pertussis,...
Zusammenfassung Hintergrund Die nosokomiale Pneumonie, die sowohl im Krankenhaus erworbene (HAP) als auch beatmungsassoziierte Pneumonie (VAP) umfasst, ist nach wie vor eine Hauptursache für Morbidität und Mortalität bei hospitalisierten Erwachsenen. Bei sich verändernden Erregerprofilen aufkommenden Resistenzmustern bietet vorliegende aktualisierte S3-Leitlinie (AWMF-Register-Nr. 020-013) evidenzbasierte Empfehlung zur Verbesserung der Diagnose, Risikostratifizierung Behandlung nosokomialen...
This summary of the update guidelines for management lower respiratory tract infections and community-acquired pneumonia (CAP) provides an overview on structure key points provided in this document. It is based Oxford Centre Evidence Based Medicine.
Several biomarkers and prognostic scores have been evaluated to predict prognosis in community-acquired pneumonia (CAP). Optimal risk stratification remains be evaluated. The aim of this study was evaluate serum cortisol as biomarker for the prediction adverse outcomes independently CRB-65 score und inflammatory a large cohort hospitalised patients with CAP. 984 CAP-patients were included. Serum measured its accuracy compared score, leucocyte count C-reactive protein. Predefined endpoints...