A5026190949- IL-33, ST2, and ILC Pathways
- Advanced Glycation End Products research
- Immune Cell Function and Interaction
- Cardiovascular Disease and Adiposity
- Pediatric health and respiratory diseases
- Autoimmune and Inflammatory Disorders Research
- Adipokines, Inflammation, and Metabolic Diseases
- Eosinophilic Esophagitis
- Natural Antidiabetic Agents Studies
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Clostridium difficile and Clostridium perfringens research
- Pediatric Urology and Nephrology Studies
- Gut microbiota and health
- Atherosclerosis and Cardiovascular Diseases
- Infant Nutrition and Health
Charité - Universitätsmedizin Berlin
2019-2024
Humboldt-Universität zu Berlin
2018-2023
Freie Universität Berlin
2018-2023
University of Potsdam
2013-2015
This study aims to increase understanding of the connection between oxidative stress and inflammation in diabetes disease progression provide a basis for investigating improved diagnostic possibilities, treatment prevention prediabetes.Differences level biochemical markers (erythrocyte GSH/GSSG urinary 8-isoprostane), (CRP, IL-6), endothelial dysfunction (plasma homocysteine, 8-hydroxy-2-deoxy-guanosine) coagulation/fibrinolysis (C5a, D-Dimer) were determined prediabetes control...
IL-22 plays a critical role in defending against mucosal infections, but how production is regulated incompletely understood. Here, we show that mice lacking IL-33 or its receptor ST2 (IL-1RL1) were more resistant to Streptococcus pneumoniae lung infection than wild-type animals and single-nucleotide polymorphisms IL33 IL1RL1 associated with pneumococcal pneumonia humans. The effect of on S. was mediated by negative regulation innate lymphoid cells (ILCs) independent ILC2s as well IL-4 IL-13...
ABSTRACT IL-22 plays a critical role in defending against mucosal infections, but how production is regulated incompletely understood. Here, we show that mice lacking IL-33 or its receptor ST2 (IL-1RL1) were more resistant to Streptococcus pneumoniae lung infection than wild-type animals, and single nucleotide polymorphisms IL33 IL1RL1 associated with pneumococcal pneumonia humans. The effect of on S. was mediated by negative regulation innate lymphoid cells (ILCs), independent ILC2s as well...
Lange Zeit ging man von einer sterilen intrauterinen Fetalentwicklung aus. Dank neuer molekularbiologischer Methoden ist der Nachweis bakterieller DNA und die Bestimmung Bakterienstämmen möglich. Die Frage, ob fetale Darm bereits vorgeburtlich mit vitalen, kultivierbaren Bakterien besiedelt wird oder bakterielle lediglich via maternal-plazentarem Transfer in den fetalen gelangt, weiterhin ungeklärt. In einem Literaturreview konnten wir zeigen, dass bislang durchgeführten Studien insbesondere...