A5017926952- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Protein Hydrolysis and Bioactive Peptides
- Silk-based biomaterials and applications
- Dental materials and restorations
- Orthopaedic implants and arthroplasty
Athlone Institute of Technology
2022-2024
Technological University of the Shannon: Midlands Midwest
2022-2024
A large bone defect is defined as a that exceeds the regenerative capacity of bone. Nowadays, autologous grafting still gold standard treatment. In this study, hybrid tissue engineering scaffold (BTE) was designed with biocompatibility, biodegradability and adequate mechanical strength primary objectives. Chitosan (CS) biocompatible biodegradable polymer can be used in wide range applications engineering. Hydroxyapatite (HAp) fluorapatite (FAp) have potential to improve properties CS....
Bone tissue engineering (BTE) is an ongoing field of research based on clinical needs to treat delayed and non-union long bone fractures. An ideal scaffold should have a biodegradability property matching the rate new turnover, be non-toxic, good mechanical properties, mimic natural extracellular matrix induce regeneration. In this study, biodegradable chitosan (CS) scaffolds were prepared with combinations bioactive ceramics, namely hydroxyapatite (HAp), tricalcium phosphate-α (TCP- α),...
Bone has the ability to heal itself; however, bone defects fail once damage exceeds a critical size. regeneration remains significant clinical challenge, with autograft considered ideal graft material due its sufficient porosity, osteogenic cells, and biological growth factors. However, limitations grafting, such as limited stock high resorption rates, have led great deal of research into developing substitutes. The P28 peptide is small molecule bioactive biomimetic alternative mimic...