Bianca Simonassi-Paiva

ORCID: 0000-0002-8486-1275
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About
Contact & Profiles
Research Areas
  • Electrohydrodynamics and Fluid Dynamics
  • Electrospun Nanofibers in Biomedical Applications
  • Microfluidic and Capillary Electrophoresis Applications
  • Polysaccharides and Plant Cell Walls
  • Bone Tissue Engineering Materials
  • Phytochemical compounds biological activities
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Herbal Medicine Research Studies
  • Silk-based biomaterials and applications
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Telomeres, Telomerase, and Senescence
  • Online Learning and Analytics
  • Medicinal Plants and Bioactive Compounds
  • Environmental Education and Sustainability
  • Protein Hydrolysis and Bioactive Peptides
  • Advancements in Transdermal Drug Delivery
  • Advanced Drug Delivery Systems
  • Nanoparticle-Based Drug Delivery
  • Mass Spectrometry Techniques and Applications

Athlone Institute of Technology
2020-2024

Technological University of the Shannon: Midlands Midwest
2024

Core-shell particles composed of polycaprolactone/polyvinyl alcohol (PCL/PVA) with pH sensitive properties were successfully fabricated by co-axial electrospraying in which PVA and PCL formed the shell core layers respectively. The core–shell structure was confirmed FTIR, DSC SEM analysis. No chemical interaction between observed FTIR RAD001 loaded showed a sustained dependent drug release assayed via our previously developed HPLC method. After indirect treatment PF-A cells for 24 h 5 days...

10.1016/j.ejpb.2024.114376 article EN cc-by European Journal of Pharmaceutics and Biopharmaceutics 2024-06-18

Bone has the ability to heal itself; however, bone defects fail once damage exceeds a critical size. regeneration remains significant clinical challenge, with autograft considered ideal graft material due its sufficient porosity, osteogenic cells, and biological growth factors. However, limitations grafting, such as limited stock high resorption rates, have led great deal of research into developing substitutes. The P28 peptide is small molecule bioactive biomimetic alternative mimic...

10.3390/molecules29174208 article EN cc-by Molecules 2024-09-05

This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for localized delivery chemotherapeutic drugs. will help reduce relapse by eradicating cancerous cells margin cervical tumors. The is very common formulation that easy manufacture, place vagina, and has low cost making them ideal use developing countries. A combination disulfiram 5-fluorouracil, which are both off-patent drugs provide different modes action, were evaluated....

10.3390/pharmaceutics12121185 article EN cc-by Pharmaceutics 2020-12-06

A high level of transparency in reported research is critical for several reasons, such as ensuring an acceptable trustworthiness and enabling replication. Transparency qualitative permits the identification specific circumstances which are associated with findings observations. Thus, important repeatability original studies explorations transferability findings. There has been no investigation into levels technology education to date. With a position that increasing would be beneficial,...

10.35542/osf.io/p9ubt preprint EN 2021-08-10
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