Coronavirus pneumonia is accompanied by rapid virus replication, where a large number of inflammatory cell infiltration and cytokine storm may lead to acute lung injury, respiratory distress syndrome (ARDS) death. The uncontrolled release pro-inflammatory cytokines, including interleukin (IL)-1β IL-6, associated with ARDS. This constituted the first study report on variability in physicochemical properties β-glucans extracts from same edible mushroom Lentinus edodes reduction these cytokines...

The use of biodegradable polymers in tissue engineering has been widely researched due to their ability degrade and release components a controlled manner, allowing for the potential regeneration tissues. Melt blending is common method controlling degradation rate these polymers, which involves combining materials molten state create homogenous mixture with tailored properties. In this study, polycaprolactone (PCL) was melt blended hydrophilic poly (ethylene oxide) (PEO) different molecular...

Pastures serve as the primary source of grass and forage plants for grazing livestock, requiring adequate nutrient input to sustain growth soil fertility. Slurry from livestock industry is widely utilized a sustainable cost-effective alternative chemical fertilizers. Microorganisms within slurry–pasture system are essential breaking down organic matter, facilitating cycling, improving health. However, mismanagement or inefficient microbial decomposition can lead significant issues, such...

Minimally processed foods (MPFs), often considered ready-to-eat, do not undergo cooking and therefore require proper handling preparation to ensure safety. If handled correctly, these can serve as a pathway for diseases caused by pathogenic bacteria, including Escherichia coli Salmonella spp. The antibacterial activity of essential oils (EOs) has been increasingly studied tool controlling microorganisms in the food sector. Therefore, we aimed verify contamination MPF E. test sensitivity...

β-glucans are a large class of complex polysaccharides with bioactive properties, including immune modulation. Natural sources these compounds include yeast, oats, barley, mushrooms, and algae. Yeast is abundant in various processes, fermentation, they often discarded as waste products. The production biomolecules from resources growing trend worldwide novel being constantly identified. Yeast-derived may assist the host’s defence against infections by influencing neutrophil macrophage...

Polyurethane (PU) coatings have garnered considerable attention across diverse applications and industries, owing to their versatile physiochemical attributes. Despite widespread use, the environmental implications associated with carbon footprint raised concerns in recent years. To address this issue, we explored potential of Camelina oil as a base chemical for synthesizing polyesteramide polyols viable alternative petrochemical-based materials. Consequently, formulated biocarbon-rich...

Shellfish species, including oysters, clams, and mussels, are extensively cultured in coastal waters. Its location is determined by factors such as nutrient availability, water temperature, tidal cycle, the presence of contaminants Escherichia coli enteric viruses. With expansion intensification human activities at vicinities, anthropogenic has increased, threatening shellfish farms consumer safety give prevalent consumption raw shellfish. This literature review aims to provide a...

β-glucans are complex polysaccharides that found in several plants and foods, including mushrooms. display an array of potentially therapeutic properties.

Bacterial infection remains the main cause of acute respiratory distress syndrome and is a leading death disability in critically ill patients. Here we report on use purified β-glucan (lentinan) extracts from Lentinus edodes (Shiitake) mushroom that can reduce by multidrug-resistant clinical isolate Klebsiella pneumoniae rodent pneumonia model, likely through immunomodulation. Adult male Sprague-Dawley rats were subjected to intra-tracheal administration K. induce pulmonary sepsis randomized...

Polyelectrolyte complexes (PECs) have emerged as promising vehicles for medical applications, attributable to their non-toxicity, non-immunogenicity, and ability controlled drug release. Notably, inherent mucoadhesive properties are being leveraged sustained delivery across mucosal barriers, including vaginal, ocular, nasal, buccal membranes. This study delves into the formulation effects of chitosan-(poly)acrylic acid-based PEC vaginal tablet applications. A comparative analysis various...

Abstract This study presents the synthesis of sustainable urethane coatings derived from alkyds Camelina oil (CO) monoglycerides, offering a alternative to petrochemical resources. Utilizing immobilized lipase for low‐temperature glycerolysis reaction, high‐yield monoglycerides were obtained CO. These then reacted with dibasic acids (phthalic, succinic, and maleic anhydride) produce alkyd diols, confirmed by both nuclear magnetic resonance (NMR) Fourier transform infrared (FTIR)...

Development of integrated multi-trophic aquaculture (IMTA) systems constitutes a step change in the sustainable production freshwater fish to meet emerging needs for high-protein foods globally. Recently, there has been paradigm shift away from harvesting peat as fuel towards development wettable peatland innovation (termed 'paludiculture'), such aquaculture. Such eco-innovations support carbon sequestration and align with balanced environmental approach protecting biodiversity. This novel...

Polylactide–polyglycolide (PLGA) is one of the most attractive polymeric biomaterials used to fabricate medical devices for drug delivery and tissue engineering applications. Nevertheless, utilization PLGA in load-bearing applications restricted due its inadequate mechanical properties. This study examines potential recombinant silk fibroin (eADF4), a readily producible biomaterial, as reinforcing agent PLGA. The PLGA/eADF4 composite membranes were developed by using process electrospinning....

This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for localized delivery chemotherapeutic drugs. will help reduce relapse by eradicating cancerous cells margin cervical tumors. The is very common formulation that easy manufacture, place vagina, and has low cost making them ideal use developing countries. A combination disulfiram 5-fluorouracil, which are both off-patent drugs provide different modes action, were evaluated....

Mechanical ventilation (MV) is a life-saving approach in critically ill patients. However, it may affect the diaphragmatic structure and function, beyond lungs. Levosimendan calcium sensitizer widely used clinics to improve cardiac contractility acute heart failure In vitro studies have demonstrated that levosimendan increased force-generating capacity of diaphragm chronic obstructive pulmonary disease Thus aim this study was evaluate effects administration an animal model ventilator-induced...